Saturday, April 30, 2016

Nuplazid (pimavanserin) tablets approved to treat hallucinations and delusions

Nuplazid (pimavanserin) tablets approved to treat hallucinations and delusions:

Dementia Big
The U.S. Food and Drug Administration today approved Nuplazid (pimavanserin) tablets, the first drug approved to treat hallucinations and delusions associated with psychosis experienced by some people with Parkinson’s disease.


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Nuplazid (pimavanserin) tablets approved to treat hallucinations and delusions

The U.S. Food and Drug Administration today approved Nuplazid (pimavanserin) tablets, the first drug approved to treat hallucinations and delusions associated with psychosis experienced by some people with Parkinson’s disease.

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Nuplazid (pimavanserin) tablets approved to treat hallucinations and delusions

The U.S. Food and Drug Administration today approved Nuplazid (pimavanserin) tablets, the first drug approved to treat hallucinations and delusions associated with psychosis experienced by some people with Parkinson’s disease.

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Life-course blood pressure in relation to brain volumes

Life-course blood pressure in relation to brain volumes:

Dementia Big
The impact of blood pressure on brain volumes may be time-dependent or pattern-dependent.


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Life-course blood pressure in relation to brain volumes

The impact of blood pressure on brain volumes may be time-dependent or pattern-dependent.

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Life-course blood pressure in relation to brain volumes

The impact of blood pressure on brain volumes may be time-dependent or pattern-dependent.

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http://ift.tt/1XZlnhm

Friday, April 29, 2016

Hyperphosphorylation determines both the spread and the morphology of tau pathology

Hyperphosphorylation determines both the spread and the morphology of tau pathology:

Dementia Big
Neurofibrillary pathology of abnormally hyperphosphorylated tau (P-tau) is a hallmark of Alzheimer’s disease (AD) and other tauopathies. Tau pathology can be experimentally induced and propagated. However, what induces the prion-like transmission character to tau and produces morphologically distinct tau lesions remains elusive.


http://ift.tt/1YWdd9D

Hyperphosphorylation determines both the spread and the morphology of tau pathology

Neurofibrillary pathology of abnormally hyperphosphorylated tau (P-tau) is a hallmark of Alzheimer’s disease (AD) and other tauopathies. Tau pathology can be experimentally induced and propagated. However, what induces the prion-like transmission character to tau and produces morphologically distinct tau lesions remains elusive.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1WuViYL

Hyperphosphorylation determines both the spread and the morphology of tau pathology

Neurofibrillary pathology of abnormally hyperphosphorylated tau (P-tau) is a hallmark of Alzheimer’s disease (AD) and other tauopathies. Tau pathology can be experimentally induced and propagated. However, what induces the prion-like transmission character to tau and produces morphologically distinct tau lesions remains elusive.

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http://ift.tt/1YWdbyE

Thursday, April 28, 2016

New study reveals increased risk of dementia in patients with rosacea

New study reveals increased risk of dementia in patients with rosacea:

Dementia Big
A new study has uncovered an increased risk of dementia–in particular Alzheimer’s disease–in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.


http://ift.tt/1N3whCc

Diabetes drug could influence brain activity in Alzheimer's

Diabetes drug could influence brain activity in Alzheimer's:

Dementia Big
Researchers in Denmark have released findings from a small clinical trial of the diabetes drug liraglutide in people living with Alzheimer’s disease.


http://ift.tt/1qYKs17

Rosacea linked to a slightly increased risk of dementia

Rosacea linked to a slightly increased risk of dementia:

Dementia Big
A new study has uncovered an increased risk of dementia—in particular Alzheimer’s disease—in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.


http://ift.tt/1N3wjtK

Rosacea linked to a slightly increased risk of dementia

A new study has uncovered an increased risk of dementia—in particular Alzheimer’s disease—in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

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via Stopping Dementia



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via alcoholic dementia
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Diabetes drug could influence brain activity in Alzheimer’s

Researchers in Denmark have released findings from a small clinical trial of the diabetes drug liraglutide in people living with Alzheimer’s disease.

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via Stopping Dementia



from WordPress http://ift.tt/1pKPc9D
via alcoholic dementia
http://ift.tt/1N3whlG

New study reveals increased risk of dementia in patients with rosacea

A new study has uncovered an increased risk of dementia–in particular Alzheimer’s disease–in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

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via Stopping Dementia



from WordPress http://ift.tt/26xQiqK
via alcoholic dementia
http://ift.tt/1qYKtCf

New study reveals increased risk of dementia in patients with rosacea

A new study has uncovered an increased risk of dementia–in particular Alzheimer’s disease–in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

from Dementia Big http://ift.tt/1qYvNCZ via alcoholic dementia


http://ift.tt/1N3whlz

Diabetes drug could influence brain activity in Alzheimer's

Researchers in Denmark have released findings from a small clinical trial of the diabetes drug liraglutide in people living with Alzheimer’s disease.

from Dementia Big http://ift.tt/24mgaEc via alcoholic dementia


http://ift.tt/1TyQ2ki

Rosacea linked to a slightly increased risk of dementia

A new study has uncovered an increased risk of dementia—in particular Alzheimer’s disease—in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

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http://ift.tt/1rCD1xv

Wednesday, April 27, 2016

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Amyloid-beta (Aβ) peptide oligomerization plays a central role in the pathogenesis of Alzheimer’s disease (AD), and Aβ oligomers are collectively considered an appealing therapeutic target for the treatment of AD. However, the molecular mechanisms leading to the pathologic accumulation of oligomers are unclear, and the exact structural composition of oligomers is being debated. Using targeted and quantitative mass spectrometry, we reveal site-specific Aβ autocleavage during the early phase of aggregation, producing a typical Aβ fragment signature and that truncated Aβ peptides can form stable oligomeric complexes with full-length Aβ peptide.

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via Stopping Dementia



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Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint:

Dementia Big
Amyloid-beta (Aβ) peptide oligomerization plays a central role in the pathogenesis of Alzheimer’s disease (AD), and Aβ oligomers are collectively considered an appealing therapeutic target for the treatment of AD. However, the molecular mechanisms leading to the pathologic accumulation of oligomers are unclear, and the exact structural composition of oligomers is being debated. Using targeted and quantitative mass spectrometry, we reveal site-specific Aβ autocleavage during the early phase of aggregation, producing a typical Aβ fragment signature and that truncated Aβ peptides can form stable oligomeric complexes with full-length Aβ peptide.


http://ift.tt/1NUFqI7

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Amyloid-beta (Aβ) peptide oligomerization plays a central role in the pathogenesis of Alzheimer’s disease (AD), and Aβ oligomers are collectively considered an appealing therapeutic target for the treatment of AD. However, the molecular mechanisms leading to the pathologic accumulation of oligomers are unclear, and the exact structural composition of oligomers is being debated. Using targeted and quantitative mass spectrometry, we reveal site-specific Aβ autocleavage during the early phase of aggregation, producing a typical Aβ fragment signature and that truncated Aβ peptides can form stable oligomeric complexes with full-length Aβ peptide.

from Dementia Big http://ift.tt/1SztAFf via alcoholic dementia


http://ift.tt/26vpsje

Tuesday, April 26, 2016

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer's disease

Researchers testing the potential positive effects of “micro-injury” by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer’s disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.

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http://ift.tt/1SzxBtp

Scientists discover pathway that may lead to Alzheimer's disease

Today, researchers at the Fisher Center for Alzheimer’s Research Foundation report the results of two new studies conducted by the Fisher Center scientists at Rockefeller University, led by Nobel Laureate Dr. Paul Greengard, in the quest to find a cure for Alzheimer’s disease.

from Dementia Big http://ift.tt/1Spjpqd via alcoholic dementia


http://ift.tt/1VBk3DH

Hearing aid use improves cognitive function in hearing-impaired older adults

A study conducted by researchers at Columbia University Medical Center found that older adults who used a hearing aid performed significantly better on cognitive tests than those who did not use a hearing aid, despite having poorer hearing. The study was published online in the American Journal of Geriatric Psychiatry.

from Dementia Big http://ift.tt/1NOX3Jp via alcoholic dementia


http://ift.tt/23530ZJ

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer's disease

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer's disease:

Dementia Big
Researchers testing the potential positive effects of “micro-injury” by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer’s disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.


http://ift.tt/234R7CV

Scientists discover pathway that may lead to Alzheimer's disease

Scientists discover pathway that may lead to Alzheimer's disease:

Dementia Big
Today, researchers at the Fisher Center for Alzheimer’s Research Foundation report the results of two new studies conducted by the Fisher Center scientists at Rockefeller University, led by Nobel Laureate Dr. Paul Greengard, in the quest to find a cure for Alzheimer’s disease.


http://ift.tt/1VRnh6s

Hearing aid use improves cognitive function in hearing-impaired older adults

Hearing aid use improves cognitive function in hearing-impaired older adults:

Dementia Big
A study conducted by researchers at Columbia University Medical Center found that older adults who used a hearing aid performed significantly better on cognitive tests than those who did not use a hearing aid, despite having poorer hearing. The study was published online in the American Journal of Geriatric Psychiatry.


http://ift.tt/234R7mD

Hearing aid use improves cognitive function in hearing-impaired older adults

A study conducted by researchers at Columbia University Medical Center found that older adults who used a hearing aid performed significantly better on cognitive tests than those who did not use a hearing aid, despite having poorer hearing. The study was published online in the American Journal of Geriatric Psychiatry.

from Dementia Big http://ift.tt/1NOX3Jp
via Stopping Dementia



from WordPress http://ift.tt/1NyjiIE
via alcoholic dementia
http://ift.tt/1SJ1JEP

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer’s disease

Researchers testing the potential positive effects of “micro-injury” by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer’s disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.

from Dementia Big http://ift.tt/1MW3yPB
via Stopping Dementia



from WordPress http://ift.tt/1SIXDwr
via alcoholic dementia
http://ift.tt/1VBaeFQ

Scientists discover pathway that may lead to Alzheimer’s disease

Today, researchers at the Fisher Center for Alzheimer’s Research Foundation report the results of two new studies conducted by the Fisher Center scientists at Rockefeller University, led by Nobel Laureate Dr. Paul Greengard, in the quest to find a cure for Alzheimer’s disease.

from Dementia Big http://ift.tt/1Spjpqd
via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1SJ1GJp

Monday, April 25, 2016

Homocysteine tied to Alzheimer’s via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer’s disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to a study published online April 19 in the Journal of Thrombosis and Haemostasis.

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via Stopping Dementia



from WordPress http://ift.tt/1pA8DC1
via alcoholic dementia
http://ift.tt/1MUHpRR

A participatory research project tackling Alzheimer’s disease

Earlier this year, we introduced you to WeCureALZ – a groundbreaking new project that for the first time is set to use the power of citizen science to conduct Alzheimer’s research. Enabled by the support of the BrightFocus Foundation, the team is already preparing for the alpha testing of our first online activity – a game that will allow everyone to search for stalled capillaries in the brains of Alzheimer’s-affected mice.

from Dementia Big http://ift.tt/1NL6l99
via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1XTCgtM

Type 2 diabetes can lead to hearing impairment

A review of studies of possible linkages between type 2 diabetes and hearing impairment concludes there is compelling evidence that diabetes can damage the auditory system, and that clinicians should include hearing testing in managing type 2 diabetes. The survey results were published in an article titled, “Type 2 Diabetes and Hearing Impairment” in the journal, Current Diabetes Reports.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1MUHpRL

Molecular mechanism of prion-like tau-induced neurodegeneration

Accumulation of hyperphosphorylated tau and the disruption of microtubules are correlated with synaptic loss and pathology of Alzheimer’s disease (AD). Impaired cognitive function and pathology of AD is correlated with this lesion. This review looks at the mechanism of neurodegeneration, the prion-like behavior of tau in its interaction with normal MAPs in correlation with tau hyperphosphorylation.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1XTCe4Z

O-GlcNAcylation: A regulator of tau pathology and neurodegeneration

O-GlcNAcylation is the posttranslational modification of intracellular proteins by O-linked β-N-acetylglucosamine (O-GlcNAc). The discovery of O-GlcNAc modification of tau and its impact on tau phosphorylation has attracted recent research interest in O-GlcNAc studies in the Alzheimer’s disease (AD) field. Modification of proteins by O-GlcNAc occurs extensively in the brain. The expressions and activities of the enzymes catalyzing O-GlcNAc cycling are several-fold higher in the brain than in the peripheral tissues.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1MUHqFw

Type 2 diabetes can lead to hearing impairment

Type 2 diabetes can lead to hearing impairment:

Dementia Big
A review of studies of possible linkages between type 2 diabetes and hearing impairment concludes there is compelling evidence that diabetes can damage the auditory system, and that clinicians should include hearing testing in managing type 2 diabetes. The survey results were published in an article titled, “Type 2 Diabetes and Hearing Impairment” in the journal, Current Diabetes Reports.


http://ift.tt/1NvcWK6

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction:

Dementia Big
(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer’s disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to a study published online April 19 in the Journal of Thrombosis and Haemostasis.


http://ift.tt/1Sw7hAh

O-GlcNAcylation: A regulator of tau pathology and neurodegeneration

O-GlcNAcylation: A regulator of tau pathology and neurodegeneration:

Dementia Big
O-GlcNAcylation is the posttranslational modification of intracellular proteins by O-linked β-N-acetylglucosamine (O-GlcNAc). The discovery of O-GlcNAc modification of tau and its impact on tau phosphorylation has attracted recent research interest in O-GlcNAc studies in the Alzheimer’s disease (AD) field. Modification of proteins by O-GlcNAc occurs extensively in the brain. The expressions and activities of the enzymes catalyzing O-GlcNAc cycling are several-fold higher in the brain than in the peripheral tissues.


http://ift.tt/1VySWch

A participatory research project tackling Alzheimer's disease

A participatory research project tackling Alzheimer's disease:

Dementia Big
Earlier this year, we introduced you to WeCureALZ – a groundbreaking new project that for the first time is set to use the power of citizen science to conduct Alzheimer’s research. Enabled by the support of the BrightFocus Foundation, the team is already preparing for the alpha testing of our first online activity – a game that will allow everyone to search for stalled capillaries in the brains of Alzheimer’s-affected mice.


http://ift.tt/1XTAdWx

Molecular mechanism of prion-like tau-induced neurodegeneration

Molecular mechanism of prion-like tau-induced neurodegeneration:

Dementia Big
Accumulation of hyperphosphorylated tau and the disruption of microtubules are correlated with synaptic loss and pathology of Alzheimer’s disease (AD). Impaired cognitive function and pathology of AD is correlated with this lesion. This review looks at the mechanism of neurodegeneration, the prion-like behavior of tau in its interaction with normal MAPs in correlation with tau hyperphosphorylation.


http://ift.tt/1VySV8i

Type 2 diabetes can lead to hearing impairment

A review of studies of possible linkages between type 2 diabetes and hearing impairment concludes there is compelling evidence that diabetes can damage the auditory system, and that clinicians should include hearing testing in managing type 2 diabetes. The survey results were published in an article titled, “Type 2 Diabetes and Hearing Impairment” in the journal, Current Diabetes Reports.

from Dementia Big http://ift.tt/21c8QZP via alcoholic dementia


http://ift.tt/1XTAdWt

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer’s disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to a study published online April 19 in the Journal of Thrombosis and Haemostasis.

from Dementia Big http://ift.tt/1NtKKHs via alcoholic dementia


http://ift.tt/1VySWc8

O-GlcNAcylation: A regulator of tau pathology and neurodegeneration

O-GlcNAcylation is the posttranslational modification of intracellular proteins by O-linked β-N-acetylglucosamine (O-GlcNAc). The discovery of O-GlcNAc modification of tau and its impact on tau phosphorylation has attracted recent research interest in O-GlcNAc studies in the Alzheimer’s disease (AD) field. Modification of proteins by O-GlcNAc occurs extensively in the brain. The expressions and activities of the enzymes catalyzing O-GlcNAc cycling are several-fold higher in the brain than in the peripheral tissues.

from Dementia Big http://ift.tt/1rvJfiJ via alcoholic dementia


http://ift.tt/1XTAdG8

Molecular mechanism of prion-like tau-induced neurodegeneration

Accumulation of hyperphosphorylated tau and the disruption of microtubules are correlated with synaptic loss and pathology of Alzheimer’s disease (AD). Impaired cognitive function and pathology of AD is correlated with this lesion. This review looks at the mechanism of neurodegeneration, the prion-like behavior of tau in its interaction with normal MAPs in correlation with tau hyperphosphorylation.

from Dementia Big http://ift.tt/1QxOIJX via alcoholic dementia


http://ift.tt/1VySV8e

A participatory research project tackling Alzheimer's disease

Earlier this year, we introduced you to WeCureALZ – a groundbreaking new project that for the first time is set to use the power of citizen science to conduct Alzheimer’s research. Enabled by the support of the BrightFocus Foundation, the team is already preparing for the alpha testing of our first online activity – a game that will allow everyone to search for stalled capillaries in the brains of Alzheimer’s-affected mice.

from Dementia Big http://ift.tt/1NL6l99 via alcoholic dementia


http://ift.tt/1XTAdG6

Friday, April 22, 2016

UK research allays fears over dramatic increases in dementia incidence

UK research allays fears over dramatic increases in dementia incidence:

Dementia Big
Research conducted in the UK has found a 20% drop in the incidence of dementia over the past 2 decades, leading to an estimated 41,000 fewer cases per year in people aged 65 years and older than previously expected.


http://ift.tt/1ToAe3n

Study finds low prevalence of vascular risk among Southwest US population

Study finds low prevalence of vascular risk among Southwest US population:

Dementia Big
In a newly published, pilot study in the journal Ethnicity & Disease, researchers report a relatively low prevalence of vascular risk among participants of the Southwest Heart Mind Study, especially among those treated for hypertension and hyperlipidemia despite overweight and obesity.


http://ift.tt/1SiBhmI

Unique mouse model could help study genetic origins and potential treatments for ALS

Unique mouse model could help study genetic origins and potential treatments for ALS:

Dementia Big
University of Florida Health researchers have developed a unique mouse model that will allow researchers around the world to better study the genetic origins and potential treatments for a neurodegenerative brain disease that causes amyotrophic lateral sclerosis, often referred to as ALS or Lou Gehrig’s disease, and frontotemporal dementia.


http://ift.tt/1ToAdN5

Unique mouse model could help study genetic origins and potential treatments for ALS

University of Florida Health researchers have developed a unique mouse model that will allow researchers around the world to better study the genetic origins and potential treatments for a neurodegenerative brain disease that causes amyotrophic lateral sclerosis, often referred to as ALS or Lou Gehrig’s disease, and frontotemporal dementia.

from Dementia Big http://ift.tt/1WKLN8a via alcoholic dementia


http://ift.tt/1SiBjec

UK research allays fears over dramatic increases in dementia incidence

Research conducted in the UK has found a 20% drop in the incidence of dementia over the past 2 decades, leading to an estimated 41,000 fewer cases per year in people aged 65 years and older than previously expected.

from Dementia Big http://ift.tt/1SzIq0H via alcoholic dementia


http://ift.tt/1ToAaRg

Study finds low prevalence of vascular risk among Southwest US population

In a newly published, pilot study in the journal Ethnicity & Disease, researchers report a relatively low prevalence of vascular risk among participants of the Southwest Heart Mind Study, especially among those treated for hypertension and hyperlipidemia despite overweight and obesity.

from Dementia Big http://ift.tt/1MNni7Y via alcoholic dementia


http://ift.tt/1SiBhmA

Study finds low prevalence of vascular risk among Southwest US population

In a newly published, pilot study in the journal Ethnicity & Disease, researchers report a relatively low prevalence of vascular risk among participants of the Southwest Heart Mind Study, especially among those treated for hypertension and hyperlipidemia despite overweight and obesity.

from Dementia Big http://ift.tt/1MNni7Y
via Stopping Dementia



from WordPress http://ift.tt/1SizZb6
via alcoholic dementia
http://ift.tt/1ToAaAW

UK research allays fears over dramatic increases in dementia incidence

Research conducted in the UK has found a 20% drop in the incidence of dementia over the past 2 decades, leading to an estimated 41,000 fewer cases per year in people aged 65 years and older than previously expected.

from Dementia Big http://ift.tt/1SzIq0H
via Stopping Dementia



from WordPress http://ift.tt/1SiA12L
via alcoholic dementia
http://ift.tt/1SiBje6

Unique mouse model could help study genetic origins and potential treatments for ALS

University of Florida Health researchers have developed a unique mouse model that will allow researchers around the world to better study the genetic origins and potential treatments for a neurodegenerative brain disease that causes amyotrophic lateral sclerosis, often referred to as ALS or Lou Gehrig’s disease, and frontotemporal dementia.

from Dementia Big http://ift.tt/1WKLN8a
via Stopping Dementia



from WordPress http://ift.tt/1YMdZWP
via alcoholic dementia
http://ift.tt/1ToAdMS

FAU's clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia

FAU's clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia:

Dementia Big
Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.


http://ift.tt/214IkSa

Problems finding your way around may be earliest sign of Alzheimer's disease

Problems finding your way around may be earliest sign of Alzheimer's disease:

Dementia Big
Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.


http://ift.tt/1WhtHKg

Brain's immune system triggers frontotemporal dementia

Brain's immune system triggers frontotemporal dementia:

Dementia Big
Frontotemporal dementia (FTD), the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain’s synaptic connections, according to new research led by UCSF scientists.


http://ift.tt/214IjO0

Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimer's disease clinical trial cohort

Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimer's disease clinical trial cohort:

Dementia Big
Mild-AD subjects without significant Aβ pathology represent a confounding finding for clinical trials because they may not progress clinically on the expected trajectory, adding variance into analyses where slowing of progression is being measured.


http://ift.tt/1WhtK94

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD:

Dementia Big
For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.


http://ift.tt/214IjNX

FAUs clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia

Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1WhtK8V

Brains immune system triggers frontotemporal dementia

Frontotemporal dementia (FTD), the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain’s synaptic connections, according to new research led by UCSF scientists.

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via Stopping Dementia



from WordPress http://ift.tt/23Oigjn
via alcoholic dementia
http://ift.tt/214IhWy

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

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via Stopping Dementia



from WordPress http://ift.tt/23OieYJ
via alcoholic dementia
http://ift.tt/1WhtHtP

Problems finding your way around may be earliest sign of Alzheimers disease

Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.

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via Stopping Dementia



from WordPress http://ift.tt/248b9Pw
via alcoholic dementia
http://ift.tt/214IhWo

Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimers disease clinical trial cohort

Mild-AD subjects without significant Aβ pathology represent a confounding finding for clinical trials because they may not progress clinically on the expected trajectory, adding variance into analyses where slowing of progression is being measured.

from Dementia Big http://ift.tt/1XLUrS9
via Stopping Dementia



from WordPress http://ift.tt/248b9yX
via alcoholic dementia
http://ift.tt/1WhtJSw

FAU's clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia

Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.

from Dementia Big http://ift.tt/1Sgs3qW via alcoholic dementia


http://ift.tt/214IhG2

Problems finding your way around may be earliest sign of Alzheimer's disease

Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.

from Dementia Big http://ift.tt/1NDWwK2 via alcoholic dementia


http://ift.tt/1WhtHdp

Brain's immune system triggers frontotemporal dementia

Frontotemporal dementia (FTD), the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain’s synaptic connections, according to new research led by UCSF scientists.

from Dementia Big http://ift.tt/1por7oW via alcoholic dementia


http://ift.tt/214Ijh8

Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimer's disease clinical trial cohort

Mild-AD subjects without significant Aβ pathology represent a confounding finding for clinical trials because they may not progress clinically on the expected trajectory, adding variance into analyses where slowing of progression is being measured.

from Dementia Big http://ift.tt/1XLUrS9 via alcoholic dementia


http://ift.tt/1WhtJSo

Scientists find interaction between amyloid and tau proteins that cause brain damage linked with AD

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

from Dementia Big http://ift.tt/1Qq8arW via alcoholic dementia


http://ift.tt/214IhFL

Thursday, April 21, 2016

New diagnostic approach may help physicians more efficiently screen for dementia

A tiered diagnostic approach that incorporates clinical, imaging and laboratory data may help physicians more efficiently screen for neurodegenerative disorders such as dementia, according to the consensus of a multi-disciplinary panel of experts.

from Dementia Big http://ift.tt/1YIIoVV via alcoholic dementia


http://ift.tt/26gYVWG

FAU site for first US clinical trial for Lewy Body dementia

Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.

from Dementia Big http://ift.tt/23LuaKH via alcoholic dementia


http://ift.tt/1SwbhD7

Soluble amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition

In Alzheimer’s disease (AD), pathologic amyloid-beta (Aβ) is synaptotoxic and impairs neuronal function at the microscale, influencing brain networks at the macroscale before Aβ deposition. The latter can be detected noninvasively, in vivo, using resting-state functional MRI (rsfMRI), a technique used to assess brain functional connectivity (FC).

from Dementia Big http://ift.tt/1WH7oOT via alcoholic dementia


http://ift.tt/26gYVWC

FAU site for first US clinical trial for Lewy Body dementia

FAU site for first US clinical trial for Lewy Body dementia:

Dementia Big
Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.


http://ift.tt/1SwbgPt

New diagnostic approach may help physicians more efficiently screen for dementia

New diagnostic approach may help physicians more efficiently screen for dementia:

Dementia Big
A tiered diagnostic approach that incorporates clinical, imaging and laboratory data may help physicians more efficiently screen for neurodegenerative disorders such as dementia, according to the consensus of a multi-disciplinary panel of experts.


http://ift.tt/26gYVWA

Soluble amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition

Soluble amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition:

Dementia Big
In Alzheimer’s disease (AD), pathologic amyloid-beta (Aβ) is synaptotoxic and impairs neuronal function at the microscale, influencing brain networks at the macroscale before Aβ deposition. The latter can be detected noninvasively, in vivo, using resting-state functional MRI (rsfMRI), a technique used to assess brain functional connectivity (FC).


http://ift.tt/1SwbhCY

New diagnostic approach may help physicians more efficiently screen for dementia

A tiered diagnostic approach that incorporates clinical, imaging and laboratory data may help physicians more efficiently screen for neurodegenerative disorders such as dementia, according to the consensus of a multi-disciplinary panel of experts.

from Dementia Big http://ift.tt/1YIIoVV
via Stopping Dementia



from WordPress http://ift.tt/1rprBNm
via alcoholic dementia
http://ift.tt/26gYVGi

FAU site for first US clinical trial for Lewy Body dementia

Florida Atlantic University’s Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer’s disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.

from Dementia Big http://ift.tt/23LuaKH
via Stopping Dementia



from WordPress http://ift.tt/244yJfS
via alcoholic dementia
http://ift.tt/1Swbgz9

Soluble amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition

In Alzheimer’s disease (AD), pathologic amyloid-beta (Aβ) is synaptotoxic and impairs neuronal function at the microscale, influencing brain networks at the macroscale before Aβ deposition. The latter can be detected noninvasively, in vivo, using resting-state functional MRI (rsfMRI), a technique used to assess brain functional connectivity (FC).

from Dementia Big http://ift.tt/1WH7oOT
via Stopping Dementia



from WordPress http://ift.tt/1rprz8g
via alcoholic dementia
http://ift.tt/23LPVKy

Wednesday, April 20, 2016

Early abnormalities of Alzheimer's disease: It takes two (proteins) to tango

Early abnormalities of Alzheimer's disease: It takes two (proteins) to tango:

Dementia Big
For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.


http://ift.tt/1Vl0kb5

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status:

Dementia Big
A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.


http://ift.tt/1NC6JGZ

Image: Neurologist creates image of Alzheimer's plaque in neurons

Image: Neurologist creates image of Alzheimer's plaque in neurons:

Dementia Big
The effects of the plaques on the brains of Alzheimer’s patients are devastating.


http://ift.tt/1Vl0jUu

Researchers evaluate TBI-associated risk factors in older adults

Researchers evaluate TBI-associated risk factors in older adults:

Dementia Big
Traumatic brain injury (TBI), a leading cause of death and disability, has become so common in recent times that it has been called a “silent epidemic.” And because older adults are more likely to suffer TBI, have worse outcomes, and are less likely to survive their injury than younger adults, older adults are considered a “silent population” within this epidemic.


http://ift.tt/1NC6JqD

Navigation skill test could diagnose Alzheimer's long before memory fails

Navigation skill test could diagnose Alzheimer's long before memory fails:

Dementia Big
Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.


http://ift.tt/1Vl0hfr

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium:

Dementia Big
In a study published in the Journal of the American Geriatrics Society, researchers examined whether or not antipsychotic drugs, which are sometimes used to prevent or treat delirium, are effective.


http://ift.tt/1NC6Him

Mortality risk in current and new antipsychotic AD users: Large scale Japanese study

Mortality risk in current and new antipsychotic AD users: Large scale Japanese study:

Dementia Big
We studied the mortality risk of long term and new antipsychotic drug use in Alzheimer’s disease (AD) patients in Japan to determine improved treatment protocols.


http://ift.tt/1Vl0hfi

Early abnormalities of Alzheimers disease: It takes two (proteins) to tango

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

from Dementia Big http://ift.tt/1SkPOuy
via Stopping Dementia



from WordPress http://ift.tt/1Sup1OM
via alcoholic dementia
http://ift.tt/1NC6H1U

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

from Dementia Big http://ift.tt/1MHYRc2
via Stopping Dementia



from WordPress http://ift.tt/1SwvdsK
via alcoholic dementia
http://ift.tt/1Vl0jnz

Researchers evaluate TBI-associated risk factors in older adults

Traumatic brain injury (TBI), a leading cause of death and disability, has become so common in recent times that it has been called a “silent epidemic.” And because older adults are more likely to suffer TBI, have worse outcomes, and are less likely to survive their injury than younger adults, older adults are considered a “silent population” within this epidemic.

from Dementia Big http://ift.tt/26eQuuY
via Stopping Dementia



from WordPress http://ift.tt/1Sup1OC
via alcoholic dementia
http://ift.tt/1NC6ITp

Image: Neurologist creates image of Alzheimers plaque in neurons

The effects of the plaques on the brains of Alzheimer’s patients are devastating.

from Dementia Big http://ift.tt/23ZKOTz
via Stopping Dementia



from WordPress http://ift.tt/1SwvcVv
via alcoholic dementia
http://ift.tt/1T0gXmi

Navigation skill test could diagnose Alzheimers long before memory fails

Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.

from Dementia Big http://ift.tt/26eEdH3
via Stopping Dementia



from WordPress http://ift.tt/1SwvcFf
via alcoholic dementia
http://ift.tt/1WeJ5ao

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium

In a study published in the Journal of the American Geriatrics Society, researchers examined whether or not antipsychotic drugs, which are sometimes used to prevent or treat delirium, are effective.

from Dementia Big http://ift.tt/1qYQXkL
via Stopping Dementia



from WordPress http://ift.tt/1SuoZqf
via alcoholic dementia
http://ift.tt/1T0gVLi

Mortality risk in current and new antipsychotic AD users: Large scale Japanese study

We studied the mortality risk of long term and new antipsychotic drug use in Alzheimer’s disease (AD) patients in Japan to determine improved treatment protocols.

from Dementia Big http://ift.tt/1Ss9a33
via Stopping Dementia



from WordPress http://ift.tt/1Sup1y5
via alcoholic dementia
http://ift.tt/1WeJ5ak

Early abnormalities of Alzheimer's disease: It takes two (proteins) to tango

For years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheimer’s disease (AD). Which one is the driving force behind dementia? The answer: both of them, according to a new study by researchers at the Douglas Mental Health University Institute.

from Dementia Big http://ift.tt/1SkPOuy via alcoholic dementia


http://ift.tt/20YEha2

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

from Dementia Big http://ift.tt/1MHYRc2 via alcoholic dementia


http://ift.tt/1rlXB50

Image: Neurologist creates image of Alzheimer's plaque in neurons

The effects of the plaques on the brains of Alzheimer’s patients are devastating.

from Dementia Big http://ift.tt/23ZKOTz via alcoholic dementia


http://ift.tt/20YEiL8

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium

In a study published in the Journal of the American Geriatrics Society, researchers examined whether or not antipsychotic drugs, which are sometimes used to prevent or treat delirium, are effective.

from Dementia Big http://ift.tt/1qYQXkL via alcoholic dementia


http://ift.tt/1rlXzKx

Researchers evaluate TBI-associated risk factors in older adults

Traumatic brain injury (TBI), a leading cause of death and disability, has become so common in recent times that it has been called a “silent epidemic.” And because older adults are more likely to suffer TBI, have worse outcomes, and are less likely to survive their injury than younger adults, older adults are considered a “silent population” within this epidemic.

from Dementia Big http://ift.tt/26eQuuY via alcoholic dementia


http://ift.tt/20YEh9K

Mortality risk in current and new antipsychotic AD users: Large scale Japanese study

We studied the mortality risk of long term and new antipsychotic drug use in Alzheimer’s disease (AD) patients in Japan to determine improved treatment protocols.

from Dementia Big http://ift.tt/1Ss9a33 via alcoholic dementia


http://ift.tt/1rlXAxT

Navigation skill test could diagnose Alzheimer's long before memory fails

Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.

from Dementia Big http://ift.tt/26eEdH3 via alcoholic dementia


http://ift.tt/20YEiuu

Tuesday, April 19, 2016

Half of long-stay nursing home residents go to hospital ED regardless of cognitive status

Half of long-stay nursing home residents go to hospital ED regardless of cognitive status:

Dementia Big
A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.


http://ift.tt/1rhY4oJ

New cases of dementia in the UK fall by 20 percent over two decades

New cases of dementia in the UK fall by 20 percent over two decades:

Dementia Big
The UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to an estimated 40,000 fewer cases of dementia than previously predicted. However, the study, published today in Nature Communications, suggests that the dramatic change has been observed mainly in men.


http://ift.tt/1XHSB4A

Protein research offers 'promising' potential treatment of Alzheimer's disease

Protein research offers 'promising' potential treatment of Alzheimer's disease:

Dementia Big
Research co-led by the University of Glasgow has made a potential breakthrough in the treatment of Alzheimer’s disease.


http://ift.tt/1rhY3kW

New cases of dementia in the UK fall by 20 percent over two decades

The UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to an estimated 40,000 fewer cases of dementia than previously predicted. However, the study, published today in Nature Communications, suggests that the dramatic change has been observed mainly in men.

from Dementia Big http://ift.tt/1Sqqqpp
via Stopping Dementia



from WordPress http://ift.tt/23YHrMw
via alcoholic dementia
http://ift.tt/1XHSBSe

Half of long-stay nursing home residents go to hospital ED regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

from Dementia Big http://ift.tt/22L5ewY
via Stopping Dementia



from WordPress http://ift.tt/1Vik2nP
via alcoholic dementia
http://ift.tt/1rhY48k

Protein research offers promising potential treatment of Alzheimers disease

Research co-led by the University of Glasgow has made a potential breakthrough in the treatment of Alzheimer’s disease.

from Dementia Big http://ift.tt/1NyUtqD
via Stopping Dementia



from WordPress http://ift.tt/1Vik4w0
via alcoholic dementia
http://ift.tt/1XHSAOe

New cases of dementia in the UK fall by 20 percent over two decades

The UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to an estimated 40,000 fewer cases of dementia than previously predicted. However, the study, published today in Nature Communications, suggests that the dramatic change has been observed mainly in men.

from Dementia Big http://ift.tt/1Sqqqpp via alcoholic dementia


http://ift.tt/1rhY3kF

Half of long-stay nursing home residents go to hospital ED regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

from Dementia Big http://ift.tt/22L5ewY via alcoholic dementia


http://ift.tt/1XHSBS5

Protein research offers 'promising' potential treatment of Alzheimer's disease

Research co-led by the University of Glasgow has made a potential breakthrough in the treatment of Alzheimer’s disease.

from Dementia Big http://ift.tt/1NyUtqD via alcoholic dementia


http://ift.tt/1rhY34l

Investigating plasma levels as a biomarker for Alzheimers disease

A Centre for Healthy Brain Ageing (CHeBA) paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer’s disease) and cognitive performance in an investigation of the usefulness of plasma levels as a biomarker for Alzheimer’s disease (AD).

from Dementia Big http://ift.tt/1XFc3z0
via Stopping Dementia



from WordPress http://ift.tt/23VBVue
via alcoholic dementia
http://ift.tt/1SrQnbl

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study

Identifying factors associated with lower dementia care costs is essential. We examined whether two caregiver factors were associated with lower costs of informal care.

from Dementia Big http://ift.tt/1SWnpuG
via Stopping Dementia



from WordPress http://ift.tt/1VAeNjj
via alcoholic dementia
http://ift.tt/22KgpWV

The short-term and long-term relationship between delirium andcognitive trajectory in older surgical patients

As the relationship between delirium and long-term cognitive decline has not been well-explored, we evaluated this association in a prospective study.

from Dementia Big http://ift.tt/1SWnsGG
via Stopping Dementia



from WordPress http://ift.tt/23VBTmd
via alcoholic dementia
http://ift.tt/1SrQp2R

Georgetown researchers report first case of Alzheimers disease diagnosed in HIV-positive individual

Georgetown University researchers are reporting the first case of Alzheimer’s disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer’s risk begins to escalate.

from Dementia Big http://ift.tt/23TkGcV
via Stopping Dementia



from WordPress http://ift.tt/1VAeNjp
via alcoholic dementia
http://ift.tt/22KgpWK

Gamma glutamyltransferase and risk of future dementia in middle-aged to older Finnish men: A new prospective cohort study

We assessed the association of gamma glutamyltransferase (GGT) with risk of dementia.

from Dementia Big http://ift.tt/1SWnpuv
via Stopping Dementia



from WordPress http://ift.tt/1VAeNj8
via alcoholic dementia
http://ift.tt/1SrQoMD

ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model

Transition to bathing or dressing disability is a milestone in the evolution of dementia. We examined the transition to disability in these specific activities and considered death to be a competitive event and age and sex to be prognostic factors.

from Dementia Big http://ift.tt/1VfmBqV
via Stopping Dementia



from WordPress http://ift.tt/23VBVdG
via alcoholic dementia
http://ift.tt/22KgolH

The short-term and long-term relationship between delirium andcognitive trajectory in older surgical patients

The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients:

Dementia Big
As the relationship between delirium and long-term cognitive decline has not been well-explored, we evaluated this association in a prospective study.


http://ift.tt/1SrQoMz

Georgetown researchers report first case of Alzheimer's disease diagnosed in HIV-positive individual

Georgetown researchers report first case of Alzheimer's disease diagnosed in HIV-positive individual:

Dementia Big
Georgetown University researchers are reporting the first case of Alzheimer’s disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer’s risk begins to escalate.


http://ift.tt/22KgpGu

Investigating plasma levels as a biomarker for Alzheimer's disease

Investigating plasma levels as a biomarker for Alzheimer's disease:

Dementia Big
A Centre for Healthy Brain Ageing (CHeBA) paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer’s disease) and cognitive performance in an investigation of the usefulness of plasma levels as a biomarker for Alzheimer’s disease (AD).


http://ift.tt/1SrQmUR

Gamma glutamyltransferase and risk of future dementia in middle-aged to older Finnish men: A new prospective cohort study

Gamma glutamyltransferase and risk of future dementia in middle-aged to older Finnish men: A new prospective cohort study:

Dementia Big
We assessed the association of gamma glutamyltransferase (GGT) with risk of dementia.


http://ift.tt/22KgpGq

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study:

Dementia Big
Identifying factors associated with lower dementia care costs is essential. We examined whether two caregiver factors were associated with lower costs of informal care.


http://ift.tt/1SrQmUN

ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model

ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model:

Dementia Big
Transition to bathing or dressing disability is a milestone in the evolution of dementia. We examined the transition to disability in these specific activities and considered death to be a competitive event and age and sex to be prognostic factors.


http://ift.tt/22KgpGm

Investigating plasma levels as a biomarker for Alzheimer's disease

A Centre for Healthy Brain Ageing (CHeBA) paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer’s disease) and cognitive performance in an investigation of the usefulness of plasma levels as a biomarker for Alzheimer’s disease (AD).

from Dementia Big http://ift.tt/1XFc3z0 via alcoholic dementia


http://ift.tt/1SrQmEv

The short-term and long-term relationship between delirium andcognitive trajectory in older surgical patients

As the relationship between delirium and long-term cognitive decline has not been well-explored, we evaluated this association in a prospective study.

from Dementia Big http://ift.tt/1SWnsGG via alcoholic dementia


http://ift.tt/22KgpGg

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study

Identifying factors associated with lower dementia care costs is essential. We examined whether two caregiver factors were associated with lower costs of informal care.

from Dementia Big http://ift.tt/1SWnpuG via alcoholic dementia


http://ift.tt/1SrQmEm

Georgetown researchers report first case of Alzheimer's disease diagnosed in HIV-positive individual

Georgetown University researchers are reporting the first case of Alzheimer’s disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer’s risk begins to escalate.

from Dementia Big http://ift.tt/23TkGcV via alcoholic dementia


http://ift.tt/22KgppZ

Gamma glutamyltransferase and risk of future dementia in middle-aged to older Finnish men: A new prospective cohort study

We assessed the association of gamma glutamyltransferase (GGT) with risk of dementia.

from Dementia Big http://ift.tt/1SWnpuv via alcoholic dementia


http://ift.tt/1SrQlQN

ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model

Transition to bathing or dressing disability is a milestone in the evolution of dementia. We examined the transition to disability in these specific activities and considered death to be a competitive event and age and sex to be prognostic factors.

from Dementia Big http://ift.tt/1VfmBqV via alcoholic dementia


http://ift.tt/22KgnON

Saturday, April 16, 2016

Neuropathologic differences by race from the National Alzheimer's Coordinating Center

Compared to Caucasians, African Americans (AAs) have higher dementia prevalence, different genetic markers, and higher vascular risk factors. However, pathologic underpinnings are unknown.

from Dementia Big http://ift.tt/1Se0wmu via alcoholic dementia


http://ift.tt/1S2n3WU

Neuropathologic differences by race from the National Alzheimer’s Coordinating Center

Compared to Caucasians, African Americans (AAs) have higher dementia prevalence, different genetic markers, and higher vascular risk factors. However, pathologic underpinnings are unknown.

from Dementia Big http://ift.tt/1Se0wmu
via Stopping Dementia



from WordPress http://ift.tt/1SjCB7w
via alcoholic dementia
http://ift.tt/1YABUIo

Neuropathologic differences by race from the National Alzheimer's Coordinating Center

Neuropathologic differences by race from the National Alzheimer's Coordinating Center:

Dementia Big
Compared to Caucasians, African Americans (AAs) have higher dementia prevalence, different genetic markers, and higher vascular risk factors. However, pathologic underpinnings are unknown.


http://ift.tt/1Ng1Mst

Thursday, April 14, 2016

Self-management group rehab benefits persons with dementia

Self-management group rehab benefits persons with dementia:

Dementia Big
(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in the Journal of the American Geriatrics Society.


http://ift.tt/1TVaCgE

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support:

Dementia Big
The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.


http://ift.tt/1SP4xh7

Gene defect may point to solution for Alzheimer's

Gene defect may point to solution for Alzheimer's:

Dementia Big
Alzheimer’s disease is caused by protein (amyloid) deposition in the brain. New research at the University of Bergen (UiB) and Haukeland University Hospital shows that the protein PITRM1, which is found in mitochondria, otherwise known as the powerhouses of the cell, may be involved in the development of the disease.


http://ift.tt/1TVaC0o

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease:

Dementia Big
In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.


http://ift.tt/1SP4xgV

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in the Journal of the American Geriatrics Society.

from Dementia Big http://ift.tt/23zjn6c via alcoholic dementia


http://ift.tt/1TV9zgZ

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

from Dementia Big http://ift.tt/1oY7Z0P via alcoholic dementia


http://ift.tt/1SP3spr

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.

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Gene defect may point to solution for Alzheimer's

Alzheimer’s disease is caused by protein (amyloid) deposition in the brain. New research at the University of Bergen (UiB) and Haukeland University Hospital shows that the protein PITRM1, which is found in mitochondria, otherwise known as the powerhouses of the cell, may be involved in the development of the disease.

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Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in the Journal of the American Geriatrics Society.

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NYU Stern innovation expert uncovers new link between diabetes and Alzheimer’s disease

In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.

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National plan outlines milestones, strategies for Alzheimer’s patient care and caregiver support

The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

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Gene defect may point to solution for Alzheimer’s

Alzheimer’s disease is caused by protein (amyloid) deposition in the brain. New research at the University of Bergen (UiB) and Haukeland University Hospital shows that the protein PITRM1, which is found in mitochondria, otherwise known as the powerhouses of the cell, may be involved in the development of the disease.

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via Stopping Dementia



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via alcoholic dementia
http://ift.tt/1Se2m9c

Wednesday, April 13, 2016

Biopsy of submandibular gland can help identify pathology of Parkinson’s disease, dementia with Lewy bodies

Accurate diagnosis of Parkinson’s disease, and the related disease “dementia with Lewy bodies,” can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson’s Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.

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B-School innovation professor discovers pathway between diabetes and Alzheimer’s disease

In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.

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Strategies and milestones for Alzheimer’s patient and caregiver support outlined

The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

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Strategies and milestones for Alzheimer's patient and caregiver support outlined

The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

from Dementia Big http://ift.tt/1WqtF3e via alcoholic dementia


http://ift.tt/1qoyqh5

B-School innovation professor discovers pathway between diabetes and Alzheimer's disease

In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.

from Dementia Big http://ift.tt/22syGYx via alcoholic dementia


http://ift.tt/1WrrkVz

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Accurate diagnosis of Parkinson’s disease, and the related disease “dementia with Lewy bodies,” can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson’s Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.

from Dementia Big http://ift.tt/1qmOzDH via alcoholic dementia


http://ift.tt/1qoyqgZ

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies:

Dementia Big
Accurate diagnosis of Parkinson’s disease, and the related disease “dementia with Lewy bodies,” can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson’s Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.


http://ift.tt/1WrrkFj

Strategies and milestones for Alzheimer's patient and caregiver support outlined

Strategies and milestones for Alzheimer's patient and caregiver support outlined:

Dementia Big
The National Alzheimer’s Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan’s biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.


http://ift.tt/1qoypK8

B-School innovation professor discovers pathway between diabetes and Alzheimer's disease

B-School innovation professor discovers pathway between diabetes and Alzheimer's disease:

Dementia Big
In a new paper published by The Journal of Alzheimer’s Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer’s disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer’s disease.


http://ift.tt/1WrrnRw

Tuesday, April 12, 2016

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).

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Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them–similarly to how the plastic casing of an electric cable insulates the copper wire within–allowing electrical and chemical impulses to travel faster.

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Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them–similarly to how the plastic casing of an electric cable insulates the copper wire within–allowing electrical and chemical impulses to travel faster.

from Dementia Big http://ift.tt/1T14mSn via alcoholic dementia


http://ift.tt/1SxaGhg

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).

from Dementia Big http://ift.tt/1S85Ytr via alcoholic dementia


http://ift.tt/25XRxzo

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Abnormally active Rab5 protein leads to early development of neurodegenerative disease:

Dementia Big
Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).


http://ift.tt/1SxaEGg

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists:

Dementia Big
More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them–similarly to how the plastic casing of an electric cable insulates the copper wire within–allowing electrical and chemical impulses to travel faster.


http://ift.tt/1qOd6m8

Monday, April 11, 2016

Dysfunctional endosomes are early sign of neurodegeneration

Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).

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http://ift.tt/20wMKB2

Colonic diverticular disease linked to dementia risk

(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in the Journal of Gastroenterology and Hepatology.

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http://ift.tt/1ViUcQv

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

Identifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer’s disease. The Alzheimer’s disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer’s disease based on high dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for to prediction of cognitive performance.

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http://ift.tt/20wMLVE

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations

How the human brain processes the words we hear and constructs complex concepts is still somewhat of a mystery to the neuroscience community. Transcranial direct current stimulation (tDCS) can alter our language processing, allowing for faster comprehension of meaningful word combinations, according to new research from the department of Neurology the Perelman School of Medicine at the University of Pennsylvania. The work is published in the Journal of Neuroscience.

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http://ift.tt/1ViUc2I

Colonic diverticular disease linked to dementia risk

(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in the Journal of Gastroenterology and Hepatology.

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Dysfunctional endosomes are early sign of neurodegeneration

Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).

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via Stopping Dementia



from WordPress http://ift.tt/1WotAgo
via alcoholic dementia
http://ift.tt/25VSzvQ

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations

How the human brain processes the words we hear and constructs complex concepts is still somewhat of a mystery to the neuroscience community. Transcranial direct current stimulation (tDCS) can alter our language processing, allowing for faster comprehension of meaningful word combinations, according to new research from the department of Neurology the Perelman School of Medicine at the University of Pennsylvania. The work is published in the Journal of Neuroscience.

from Dementia Big http://ift.tt/23xnLPP
via Stopping Dementia



from WordPress http://ift.tt/1WotAgi
via alcoholic dementia
http://ift.tt/1SuEuLJ

Crowdsourced estimation of cognitive decline and resilience in Alzheimer’s disease

Identifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer’s disease. The Alzheimer’s disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer’s disease based on high dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for to prediction of cognitive performance.

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via Stopping Dementia



from WordPress http://ift.tt/22q7UAc
via alcoholic dementia
http://ift.tt/25VSxE6

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations:

Dementia Big
How the human brain processes the words we hear and constructs complex concepts is still somewhat of a mystery to the neuroscience community. Transcranial direct current stimulation (tDCS) can alter our language processing, allowing for faster comprehension of meaningful word combinations, according to new research from the department of Neurology the Perelman School of Medicine at the University of Pennsylvania. The work is published in the Journal of Neuroscience.


http://ift.tt/1XrUF0F

Colonic diverticular disease linked to dementia risk

Colonic diverticular disease linked to dementia risk:

Dementia Big
(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in the Journal of Gastroenterology and Hepatology.


http://ift.tt/1VOTh9a

Dysfunctional endosomes are early sign of neurodegeneration

Dysfunctional endosomes are early sign of neurodegeneration:

Dementia Big
Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).


http://ift.tt/1XrUF0x

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease:

Dementia Big
Identifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer’s disease. The Alzheimer’s disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer’s disease based on high dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for to prediction of cognitive performance.


http://ift.tt/1VOTgST

Why do people with Alzheimer's stop recognizing their loved ones?

Alzheimer’s not only steals people’s memories but also their ability to recognize faces, which widens the gulf between people with this disease and their loved ones. A recent study has demonstrated that, beyond causing memory problems, Alzheimer’s disease also impairs visual face perception. This finding may help families better understand their loved one’s inevitable difficulties and lead to new avenues to postpone this painful aspect of the disease. Research in this area by the team of Dr. Sven Joubert, PhD, a researcher at the Centre de recherche de l'Institut universitaire de gériatrie de Montréal and a professor with the Department of Psychology at Université de Montréal, will be published tomorrow in the Journal of Alzheimer’s Disease.

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http://ift.tt/1SrYvCn

Why do people with Alzheimer’s stop recognizing their loved ones?

Alzheimer’s not only steals people’s memories but also their ability to recognize faces, which widens the gulf between people with this disease and their loved ones. A recent study has demonstrated that, beyond causing memory problems, Alzheimer’s disease also impairs visual face perception. This finding may help families better understand their loved one’s inevitable difficulties and lead to new avenues to postpone this painful aspect of the disease. Research in this area by the team of Dr. Sven Joubert, PhD, a researcher at the Centre de recherche de l’Institut universitaire de gériatrie de Montréal and a professor with the Department of Psychology at Université de Montréal, will be published tomorrow in the Journal of Alzheimer’s Disease.

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Why do people with Alzheimer's stop recognizing their loved ones?

Why do people with Alzheimer's stop recognizing their loved ones?:

Dementia Big
Alzheimer’s not only steals people’s memories but also their ability to recognize faces, which widens the gulf between people with this disease and their loved ones. A recent study has demonstrated that, beyond causing memory problems, Alzheimer’s disease also impairs visual face perception. This finding may help families better understand their loved one’s inevitable difficulties and lead to new avenues to postpone this painful aspect of the disease. Research in this area by the team of Dr. Sven Joubert, PhD, a researcher at the Centre de recherche de l'Institut universitaire de gériatrie de Montréal and a professor with the Department of Psychology at Université de Montréal, will be published tomorrow in the Journal of Alzheimer’s Disease.


http://ift.tt/1SrYwGD

Saturday, April 9, 2016

White matter hyperintensities predate Alzheimer’s onset

(HealthDay)—Autosomal dominant Alzheimer’s disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a study published online March 26 in the Annals of Neurology.

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White matter hyperintensities predate Alzheimer's onset

White matter hyperintensities predate Alzheimer's onset:

Dementia Big
(HealthDay)—Autosomal dominant Alzheimer’s disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a study published online March 26 in the Annals of Neurology.


http://ift.tt/1Ykv9dQ