People with Alzheimer’s disease who experience psychosis–including delusions and hallucinations–are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.
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People with Alzheimer’s disease who experience psychosis—including delusions and hallucinations—are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.
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People with Alzheimer’s disease who experience psychosis–including delusions and hallucinations–are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.
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People with Alzheimer’s disease who experience psychosis—including delusions and hallucinations—are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.
A combination of high blood pressure and decreased blood flow inside the brain may spur the build-up of harmful plaque and signal the onset of dementia, USC researchers have found.
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For the first time, researchers from the University of Zurich demonstrate a surprising effect of microglia, the scavenger cells of the brain: If these cells lack the TDP-43 protein, they not only remove Alzheimer’s plaques, but also synapses. This removal of synapses by these cells presumably leads to neurodegeneration observed in Alzheimer’s and other neurodegenerative diseases.
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Dementia Big
A combination of high blood pressure and decreased blood flow inside the brain may spur the build-up of harmful plaque and signal the onset of dementia, USC researchers have found.
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For the first time, researchers from the University of Zurich demonstrate a surprising effect of microglia, the scavenger cells of the brain: If these cells lack the TDP-43 protein, they not only remove Alzheimer’s plaques, but also synapses. This removal of synapses by these cells presumably leads to neurodegeneration observed in Alzheimer’s and other neurodegenerative diseases.
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Hollywood actor Ian McShane has united with Alzheimer’s Society to help families affected by dementia – in memory of his Manchester United hero dad.
Hollywood actor Ian McShane has united with Alzheimer’s Society to help families affected by dementia – in memory of his Manchester United hero dad.
Having a higher IQ during childhood is associated with a greater likelihood of staying disease free and living longer, according to research published in The BMJ.
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The connection between slowed walking speed and declining mental acuity appears to arise in the right hippocampus, a finger-shaped region buried deep in the brain at ear-level, according to a 14-year study conducted by scientists at the University of Pittsburgh Graduate School of Public Health.
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Dementia Big
Having a higher IQ during childhood is associated with a greater likelihood of staying disease free and living longer, according to research published in The BMJ.
Dementia Big
The connection between slowed walking speed and declining mental acuity appears to arise in the right hippocampus, a finger-shaped region buried deep in the brain at ear-level, according to a 14-year study conducted by scientists at the University of Pittsburgh Graduate School of Public Health.
Dementia Big
Many people living with dementia reside in long-term care facilities, where the lack of stimulation can result in behaviors such as hitting, screaming, and wandering. Common measures to avoid such “responsive” behaviors, such as antipsychotic medications and personalized recreational and music therapy programs, can cause adverse health effects in the former case and be difficult for staff to find time to carry out in the latter case. A team of human factors/ergonomics researchers helped to evaluate and refine Ambient Activity (or AA; Ambient Activity Technologies Inc.), interactive tools designed to augment existing programs and activities by alleviating boredom and increasing engagement.
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A study presented at the European Academy of Neurology Congress in Amsterdam has shown that obesity alone is not a risk factor for cognitive disorders, but commonly associated co-morbidities such as diabetes, high blood pressure and metabolic disorders are.
Many people living with dementia reside in long-term care facilities, where the lack of stimulation can result in behaviors such as hitting, screaming, and wandering. Common measures to avoid such “responsive” behaviors, such as antipsychotic medications and personalized recreational and music therapy programs, can cause adverse health effects in the former case and be difficult for staff to find time to carry out in the latter case. A team of human factors/ergonomics researchers helped to evaluate and refine Ambient Activity (or AA; Ambient Activity Technologies Inc.), interactive tools designed to augment existing programs and activities by alleviating boredom and increasing engagement.
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A study presented at the European Academy of Neurology Congress in Amsterdam has shown that obesity alone is not a risk factor for cognitive disorders, but commonly associated co-morbidities such as diabetes, high blood pressure and metabolic disorders are.
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Blekinge Institute of Technology in Sweden is leading the EU project SMART4MD which focuses on creating an app designated for people with mild dementia. The app will help these people in daily life and give them a more independent living.
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Dementia Big
Blekinge Institute of Technology in Sweden is leading the EU project SMART4MD which focuses on creating an app designated for people with mild dementia. The app will help these people in daily life and give them a more independent living.
Dementia Big
While most research on Alzheimer’s disease (AD) has focused on early diagnosis and treatment, University at Buffalo scientists are studying genetic and epigenetic factors with the ultimate goal of restoring function to patients in the later stages of the disease.
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In a new systematic review in JAMA Neurology, Michigan Medicine researchers found reason to further explore the surprising effects of zolpidem that have been observed outside the scope of its primary Food and Drug Administration approval.
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Off-label use of antipsychotic medications to treat patients with dementia has reduced dramatically in recent years due to education programs warning of increased risk of death.
While most research on Alzheimer’s disease (AD) has focused on early diagnosis and treatment, University at Buffalo scientists are studying genetic and epigenetic factors with the ultimate goal of restoring function to patients in the later stages of the disease.
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In a new systematic review in JAMA Neurology, Michigan Medicine researchers found reason to further explore the surprising effects of zolpidem that have been observed outside the scope of its primary Food and Drug Administration approval.
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Off-label use of antipsychotic medications to treat patients with dementia has reduced dramatically in recent years due to education programs warning of increased risk of death.
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Dementia Big
One in every 30 people in England, Northern Ireland and Wales now involved in the biggest ever social action movement to change perceptions of dementia.
One in every 30 people in England, Northern Ireland and Wales now involved in the biggest ever social action movement to change perceptions of dementia.
Patients with dementia may actually die sooner if their family caregivers are mentally stressed, according to a new study from the University of California, Berkeley.
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A new report published by the National Academies of Sciences, Engineering, and Medicine shows evidence supporting three interventions—cognitive training, blood pressure management for people with hypertension, and increased physical activity, which might slow down cognitive decline and the onset of dementia.
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Healthy adults carrying the gene APOE4—the strongest known genetic risk factor for Alzheimer’s disease (AD)—may struggle to adapt their brain activity to increasing cognitive demands as they get older, according to a study published in The Journal of Neuroscience. This age-related effect, which was not observed in people without the risk factor, suggests that interventions targeting cognitive decline in at-risk populations may need to begin many years before any symptoms of the disease emerge in order to be effective.
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Off-label use of antipsychotic medications to treat patients with dementia has reduced dramatically in recent years due to education programs warning of increased risk of death. However, those campaigns have not focused on care settings outside of nursing homes, leaving community-dwelling adults with dementia at risk of potentially fatal side effects, according to research published in The Journal of the American Osteopathic Association.
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Dementia Big
Patients with dementia may actually die sooner if their family caregivers are mentally stressed, according to a new study from the University of California, Berkeley.
Dementia Big
A new report published by the National Academies of Sciences, Engineering, and Medicine shows evidence supporting three interventions—cognitive training, blood pressure management for people with hypertension, and increased physical activity, which might slow down cognitive decline and the onset of dementia.
Dementia Big
Healthy adults carrying the gene APOE4—the strongest known genetic risk factor for Alzheimer’s disease (AD)—may struggle to adapt their brain activity to increasing cognitive demands as they get older, according to a study published in The Journal of Neuroscience. This age-related effect, which was not observed in people without the risk factor, suggests that interventions targeting cognitive decline in at-risk populations may need to begin many years before any symptoms of the disease emerge in order to be effective.
Dementia Big
Off-label use of antipsychotic medications to treat patients with dementia has reduced dramatically in recent years due to education programs warning of increased risk of death. However, those campaigns have not focused on care settings outside of nursing homes, leaving community-dwelling adults with dementia at risk of potentially fatal side effects, according to research published in The Journal of the American Osteopathic Association.
Dementia Big
As our populations continue to age the issue of how we deliver care to the elderly continues to be an incredibly important issue. But with the number of older people set to reach 1 billion in the next 10 years and the demand for carers increasing, could robots potentially provide the solution?
As our populations continue to age the issue of how we deliver care to the elderly continues to be an incredibly important issue. But with the number of older people set to reach 1 billion in the next 10 years and the demand for carers increasing, could robots potentially provide the solution?
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Dementia Big
In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer’s disease. Patients with Alzheimer’s disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity—disrupted electrical activity in the brain that doesn’t result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.
In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer’s disease. Patients with Alzheimer’s disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity—disrupted electrical activity in the brain that doesn’t result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.
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Going for a walk outside, reading, listening to music—these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer’s disease, suggests a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society.
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Cognitive training, blood pressure management for people with hypertension, and increased physical activity all show modest but inconclusive evidence that they can help prevent cognitive decline and dementia, but there is insufficient evidence to support a public health campaign encouraging their adoption, says a new report from the National Academies of Sciences, Engineering, and Medicine. Additional research is needed to further understand and gain confidence in their effectiveness, said the committee that conducted the study and wrote the report.
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Dementia Big
Going for a walk outside, reading, listening to music—these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer’s disease, suggests a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society.
Dementia Big
Cognitive training, blood pressure management for people with hypertension, and increased physical activity all show modest but inconclusive evidence that they can help prevent cognitive decline and dementia, but there is insufficient evidence to support a public health campaign encouraging their adoption, says a new report from the National Academies of Sciences, Engineering, and Medicine. Additional research is needed to further understand and gain confidence in their effectiveness, said the committee that conducted the study and wrote the report.
New research shows that there are several interventions that could help prevent cognitive decline. According to the latest report entitled “Preventing Cognitive Decline and Dementia: A Way Forward,” from the National Academies of Sciences, Engineering, and Medicine (NASEM), cognitive training, increase in physical activity, control of blood pressure adequately among those with a high blood pressure are all fruitful measures to reduce cognitive decline. However evidence to support these three interventions is encouraging but insufficient to justify a public health campaign focused on their adoption.
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Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body’s production of the acid that helps us digest food.
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Dementia Big
New research shows that there are several interventions that could help prevent cognitive decline. According to the latest report entitled “Preventing Cognitive Decline and Dementia: A Way Forward,” from the National Academies of Sciences, Engineering, and Medicine (NASEM), cognitive training, increase in physical activity, control of blood pressure adequately among those with a high blood pressure are all fruitful measures to reduce cognitive decline. However evidence to support these three interventions is encouraging but insufficient to justify a public health campaign focused on their adoption.
Dementia Big
Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body’s production of the acid that helps us digest food.
Dementia Big
Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body’s production of the acid that helps us digest food. Ulcers are sores that develop on the lining of our digestive system; when they develop in the upper part of the small intestine they are called “duodenal ulcers.” Reflux disease is a condition in which stomach acid or other fluids in the digestive system irritate our food pipe, also known as the esophagus.
Dementia Big
Are you seeking steps to keep your brain healthy in old age?
Dementia Big
Brisbane Airport was named Australia’s first dementia-friendly airport by Alzheimer’s Australia at the launch today in the International Terminal of a new guide to the airport for travellers with dementia.
Dementia Big
Researchers from the University of Southampton are to study tiny channels embedded in the walls of blood vessels in the brain to assess their impact on dementia.
Dementia Big
People at risk for Alzheimer’s disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have healthy patterns of glucose metabolism in their brain, according to a new UW-Madison study.
Dementia Big
An InSysBio scientific group led by Tatiana Karelina has developed a quantitative system pharmacology model of Alzheimer’s disease. The first part has been published in CPT Pharmacometrics & Systems Pharmacology, and shows how to design initial phases of clinical trials of new drugs and to interpret the data.
Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body’s production of the acid that helps us digest food. Ulcers are sores that develop on the lining of our digestive system; when they develop in the upper part of the small intestine they are called “duodenal ulcers.” Reflux disease is a condition in which stomach acid or other fluids in the digestive system irritate our food pipe, also known as the esophagus.
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Brisbane Airport was named Australia’s first dementia-friendly airport by Alzheimer’s Australia at the launch today in the International Terminal of a new guide to the airport for travellers with dementia.
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Are you seeking steps to keep your brain healthy in old age?
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People at risk for Alzheimer’s disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have healthy patterns of glucose metabolism in their brain, according to a new UW-Madison study.
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Researchers from the University of Southampton are to study tiny channels embedded in the walls of blood vessels in the brain to assess their impact on dementia.
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An InSysBio scientific group led by Tatiana Karelina has developed a quantitative system pharmacology model of Alzheimer’s disease. The first part has been published in CPT Pharmacometrics & Systems Pharmacology, and shows how to design initial phases of clinical trials of new drugs and to interpret the data.
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In a landmark judgment, the Court of Justice of the European Union, yesterday ruled that courts could consider vaccines to be the reason for an illness despite the absence of any concrete evidence to support the connection.
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Researchers at the University of Cambridge have designed antibodies that target the protein deposits in the brain associated with Alzheimer’s disease, and stop their production.
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Dementia Big
In a landmark judgment, the Court of Justice of the European Union, yesterday ruled that courts could consider vaccines to be the reason for an illness despite the absence of any concrete evidence to support the connection.
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Researchers at the University of Cambridge have designed antibodies that target the protein deposits in the brain associated with Alzheimer’s disease, and stop their production.
Dementia Big
Following the Queen’s speech today (Wednesday 21 June), read the Alzheimer’s Society comment.
Following the Queen’s speech today (Wednesday 21 June), read the Alzheimer’s Society comment.
Dementia Big
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia.
Dementia Big
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil, a major component of the Mediterranean diet. In a study published online June 21 in the Annals of Clinical and Translational Neurology, the researchers show that the consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid-beta plaques and neurofibrillary tangles in the brain—classic markers of Alzheimer’s disease.
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia.
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The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil, a major component of the Mediterranean diet. In a study published online June 21 in the Annals of Clinical and Translational Neurology, the researchers show that the consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid-beta plaques and neurofibrillary tangles in the brain—classic markers of Alzheimer’s disease.
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Dementia Big
When trying to memorize information, it is better to relate it to something meaningful rather than repeat it again and again to make it stick, according to a recent Baycrest Health Sciences study published in NeuroImage.
Dementia Big
A new position statement on the use of hormone therapy (HT) for menopausal and postmenopausal women from The North American Menopause Society has been published online today in the Society’s journal, Menopause.
Dementia Big
A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer’s disease, researchers at The University of Nottingham have found.
Dementia Big
Parkinson’s disease (PD) is commonly thought of as a movement disorder, but after years of living with PD approximately twenty five percent of patients also experience deficits in cognition that impair function.
Dementia Big
Fear of being unable to leave anything to loved ones if they develop dementia jumps 19 percentage points since election campaign.
Dementia Big
Alzheimer’s Society has today announced its biggest-ever single investment in dementia care research. £6 million has been awarded to three ‘Centres of Excellence’.
Fear of being unable to leave anything to loved ones if they develop dementia jumps 19 percentage points since election campaign.
Alzheimer’s Society has today announced its biggest-ever single investment in dementia care research. £6 million has been awarded to three ‘Centres of Excellence’.
Dementia Big
A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer’s disease, researchers at The University of Nottingham have found.
Dementia Big
Japanese scientists have developed a method to isolate and identify active compounds in plant medicines, which accurately accounts for drug behavior in the body. Using the technique, they have identified several active compounds from Drynaria Rhizome, a traditional plant medicine, which improve memory and reduce disease characteristics in a mouse model of Alzheimer’s disease.
Dementia Big
New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer’s disease significantly decreases plasma beta-amyloid levels in a population cohort. This is a very significant discovery, as many on-going drug trials in the field of Alzheimer’s disease focus on decreasing beta-amyloid levels in the brain tissue. According to the study, a 30% life-long decrease in beta-amyloid levels is not associated with detrimental effects on lipid or glucose metabolism, or on any other metabolic factors.
A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer’s disease, researchers at The University of Nottingham have found.
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Japanese scientists have developed a method to isolate and identify active compounds in plant medicines, which accurately accounts for drug behavior in the body. Using the technique, they have identified several active compounds from Drynaria Rhizome, a traditional plant medicine, which improve memory and reduce disease characteristics in a mouse model of Alzheimer’s disease.
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New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer’s disease significantly decreases plasma beta-amyloid levels in a population cohort. This is a very significant discovery, as many on-going drug trials in the field of Alzheimer’s disease focus on decreasing beta-amyloid levels in the brain tissue. According to the study, a 30% life-long decrease in beta-amyloid levels is not associated with detrimental effects on lipid or glucose metabolism, or on any other metabolic factors.
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Dementia Big
Alzheimer’s Society Cymru’s Sue Phelps has been awarded an MBE for services to dementia in Wales in the Queen’s Birthday Honours list.
Alzheimer’s Society Cymru’s Sue Phelps has been awarded an MBE for services to dementia in Wales in the Queen’s Birthday Honours list.
Dementia Big
Physical frailty is common among the elderly and is strongly associated with cognitive impairment, dementia and adverse health outcomes such as disability, hospitalization, and mortality.
Physical frailty is common among the elderly and is strongly associated with cognitive impairment, dementia and adverse health outcomes such as disability, hospitalization, and mortality.
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Dementia Big
For a sixth consecutive year, the American Academy of Neurology (AAN) will be giving away 1,000 bike helmets to children and adults on Saturday, June 17, 2017, at the Mill City Farmers Market.
For a sixth consecutive year, the American Academy of Neurology (AAN) will be giving away 1,000 bike helmets to children and adults on Saturday, June 17, 2017, at the Mill City Farmers Market.
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Dementia Big
Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute, together with scientists from Mayo Clinic’s Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).
Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute, together with scientists from Mayo Clinic’s Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).
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Swedish researchers report in an article published in the Journal of Alzheimer´s Disease that 46 percent of patients who are diagnosed with Alzheimer´s disease in Sweden live alone in their homes, in particular older women.
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The rate of death from Alzheimer’s disease in the United States increased by more than 50 percent in the past 15 years, according to new data from the Centers for Disease Control and Prevention.
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Deaths from dementia in Scotland have soared by 31 percent in a year, according to new statistics released by the National Records of Scotland today.
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A new study led by the Keck School of Medicine of University of Southern California (USC) reveals that older adults with elevated levels of brain-clogging plaques, yet normal cognition, experience faster mental decline, suggestive of Alzheimer’s disease. The study published in The Journal of the American Medical Association on June 13 presented the earliest precursor—the toxic and sticky protein as part of the disease, before symptoms arise.
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Tailored music sessions could be crucial in transforming the lives of millions of people whose speech is impacted by learning difficulties, strokes, dementia, brain damage and autism, a new study suggests.
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A new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amyloid plaques in a person’s brain predicts the rate at which his or her cognition will decline in the next four years.
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Dementia Big
Swedish researchers report in an article published in the Journal of Alzheimer´s Disease that 46 percent of patients who are diagnosed with Alzheimer´s disease in Sweden live alone in their homes, in particular older women.
Dementia Big
The rate of death from Alzheimer’s disease in the United States increased by more than 50 percent in the past 15 years, according to new data from the Centers for Disease Control and Prevention.
Dementia Big
Deaths from dementia in Scotland have soared by 31 percent in a year, according to new statistics released by the National Records of Scotland today.
Dementia Big
A new study led by the Keck School of Medicine of University of Southern California (USC) reveals that older adults with elevated levels of brain-clogging plaques, yet normal cognition, experience faster mental decline, suggestive of Alzheimer’s disease. The study published in The Journal of the American Medical Association on June 13 presented the earliest precursor—the toxic and sticky protein as part of the disease, before symptoms arise.
Dementia Big
Tailored music sessions could be crucial in transforming the lives of millions of people whose speech is impacted by learning difficulties, strokes, dementia, brain damage and autism, a new study suggests.
Dementia Big
A new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amyloid plaques in a person’s brain predicts the rate at which his or her cognition will decline in the next four years.
Dementia Big
The rate of death from Alzheimer’s disease in the United States increased by more than 50 percent in the past 15 years, according to new data from the Centers for Disease Control and Prevention.
Dementia Big
Swedish researchers report in an article published in the Journal of Alzheimer´s Disease that 46% of patients who are diagnosed with Alzheimer´s disease in Sweden live alone in their homes, in particular older women.
Dementia Big
A new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amyloid plaques in a person’s brain predicts the rate at which his or her cognition will decline in the next four years.
The rate of death from Alzheimer’s disease in the United States increased by more than 50 percent in the past 15 years, according to new data from the Centers for Disease Control and Prevention.
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Swedish researchers report in an article published in the Journal of Alzheimer´s Disease that 46% of patients who are diagnosed with Alzheimer´s disease in Sweden live alone in their homes, in particular older women.
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A new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amyloid plaques in a person’s brain predicts the rate at which his or her cognition will decline in the next four years.
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UCB today announced results from a comprehensive real world database analysis that assessed the rates of osteoporosis treatment initiation within one year following a first fracture in patients in Sweden. The data showed that only 6.6% of patients, who were treatment naive, were initiated on osteoporosis treatment. This analysis, performed by Quantify Research and funded by UCB, was presented today at the Annual European Congress of Rheumatology (EULAR) 2017 in Madrid, Spain.
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The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.
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More people die of Alzheimer’s disease than prostate and breast cancer combined. Identifying the disease before major symptoms arise is critical to preserving brain function and helping patients maintain quality of life. A new study presented at the 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) demonstrates that a single dual time-point PET scan could identify important biomarkers of Alzheimer’s disease.
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Dementia Big
UCB today announced results from a comprehensive real world database analysis that assessed the rates of osteoporosis treatment initiation within one year following a first fracture in patients in Sweden. The data showed that only 6.6% of patients, who were treatment naive, were initiated on osteoporosis treatment. This analysis, performed by Quantify Research and funded by UCB, was presented today at the Annual European Congress of Rheumatology (EULAR) 2017 in Madrid, Spain.
Dementia Big
The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.
Dementia Big
More people die of Alzheimer’s disease than prostate and breast cancer combined. Identifying the disease before major symptoms arise is critical to preserving brain function and helping patients maintain quality of life. A new study presented at the 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) demonstrates that a single dual time-point PET scan could identify important biomarkers of Alzheimer’s disease.
Dementia Big
Older adults with elevated levels of brain-clogging plaques – but otherwise normal cognition – experience faster mental decline suggestive of Alzheimer’s disease, according to a new study led by the Keck School of Medicine of USC that looked at 10 years of data.
Dementia Big
The National Institutes of Health awarded a $6 million grant to Cleveland Clinic to establish a national research consortium focused on improving the diagnosis and understanding the cause for Dementia with Lewy Bodies.
Older adults with elevated levels of brain-clogging plaques – but otherwise normal cognition – experience faster mental decline suggestive of Alzheimer’s disease, according to a new study led by the Keck School of Medicine of USC that looked at 10 years of data.
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The National Institutes of Health awarded a $6 million grant to Cleveland Clinic to establish a national research consortium focused on improving the diagnosis and understanding the cause for Dementia with Lewy Bodies.
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Dementia Big
TV chef Rosemary Shrager is uniting against dementia with Alzheimer’s Society by backing the charity’s Cupcake Day fundraising campaign this week.
TV chef Rosemary Shrager is uniting against dementia with Alzheimer’s Society by backing the charity’s Cupcake Day fundraising campaign this week.
Dementia Big
Older adults with elevated levels of brain-clogging plaques—but otherwise normal cognition—experience faster mental decline suggestive of Alzheimer’s disease, according to a new study led by the Keck School of Medicine of USC that looked at 10 years of data.
Older adults with elevated levels of brain-clogging plaques—but otherwise normal cognition—experience faster mental decline suggestive of Alzheimer’s disease, according to a new study led by the Keck School of Medicine of USC that looked at 10 years of data.
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Dementia Big
In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer’s disease.
Dementia Big
In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer’s disease (AD).
Dementia Big
Alzheimer’s Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant. In AD, the beta-amyloid precursor protein (β-APP) that is critical for normal neuronal growth, survival and repair, is improperly cleaved by specific aspartic proteases, which create fragments that form plaques of amyloid beta. These fragments aggregate outside neurons and create plaques which lead to destruction of neural signaling. The pathophysiology of AD is complex, although there are many approaches to combat the disease. Many studies target PTB domain-containing proteins in order to inhibit binding to β-APP preventing amyloid formation; whereas others target inhibition of specific aspartate proteases required for amyloid plaque formation. The role of GSK-3 is actively being studied in addition to specific inhibitors to this target for AD. Structural examples analyzed include Presenilin Homologue (PSH) protein and Mint1 which are important for the regulation of β-APP.
In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer’s disease.
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In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer’s disease (AD).
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Alzheimer’s Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant. In AD, the beta-amyloid precursor protein (β-APP) that is critical for normal neuronal growth, survival and repair, is improperly cleaved by specific aspartic proteases, which create fragments that form plaques of amyloid beta. These fragments aggregate outside neurons and create plaques which lead to destruction of neural signaling. The pathophysiology of AD is complex, although there are many approaches to combat the disease. Many studies target PTB domain-containing proteins in order to inhibit binding to β-APP preventing amyloid formation; whereas others target inhibition of specific aspartate proteases required for amyloid plaque formation. The role of GSK-3 is actively being studied in addition to specific inhibitors to this target for AD. Structural examples analyzed include Presenilin Homologue (PSH) protein and Mint1 which are important for the regulation of β-APP.
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According to a new study, pensioners and older adults over 65 who have dogs as pets tend to spend an extra 22 minutes a day walking. This can cut down the risk of their developing heart disease as well as type 2 diabetes. Some experts suggest that General Practitioners should encourage older adults to get themselves a dog to keep fit.
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Dementia Big
According to a new study, pensioners and older adults over 65 who have dogs as pets tend to spend an extra 22 minutes a day walking. This can cut down the risk of their developing heart disease as well as type 2 diabetes. Some experts suggest that General Practitioners should encourage older adults to get themselves a dog to keep fit.
A new study by researchers at the University of Montana, Universidad del Valle de México, Instituto Nacional de PediatrÃa, Boise State, and Universidad Nacional Autónoma de México, heightens concerns over the detrimental short- and long-term impact of airborne iron-rich strongly magnetic combustion-derived nanoparticles (CDNPs) present in young urbanites’ brains. Using transmission electron microscopy, the researchers documented by abundant combustion nanoparticles in neurons, glial cells, choroid plexus, and neurovascular units of Mexico City children, teens and young adults chronically exposed to concentrations above the US-EPA standards for fine particulate matter. Residents in Mexico City are exposed from conception to harmful neurotoxic air pollutants. These findings are published in the Journal of Alzheimer’s Disease.
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New guidelines have been published on the clinical and physical indicators to help ensure patients with dementia with Lewy bodies get an accurate diagnosis and the best care possible.
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Dementia Big
A new study by researchers at the University of Montana, Universidad del Valle de México, Instituto Nacional de PediatrÃa, Boise State, and Universidad Nacional Autónoma de México, heightens concerns over the detrimental short- and long-term impact of airborne iron-rich strongly magnetic combustion-derived nanoparticles (CDNPs) present in young urbanites’ brains. Using transmission electron microscopy, the researchers documented by abundant combustion nanoparticles in neurons, glial cells, choroid plexus, and neurovascular units of Mexico City children, teens and young adults chronically exposed to concentrations above the US-EPA standards for fine particulate matter. Residents in Mexico City are exposed from conception to harmful neurotoxic air pollutants. These findings are published in the Journal of Alzheimer’s Disease.
Dementia Big
New guidelines have been published on the clinical and physical indicators to help ensure patients with dementia with Lewy bodies get an accurate diagnosis and the best care possible.
Dementia Big
It’s estimated that nearly 30 percent of the 38.2 million people aged 65 or older in this country receive some form of caregiving, either for health reasons or to help manage daily activities.
It’s estimated that nearly 30 percent of the 38.2 million people aged 65 or older in this country receive some form of caregiving, either for health reasons or to help manage daily activities.
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Dementia Big
Researchers at UC San Francisco have found that older people with persistent pain show quicker declines in memory as they age and are more likely to have dementia years later, an indication that chronic pain could somehow be related to changes in the brain that contribute to dementia.
The University of Stirling’s Dementia Services Development Centre (DSDC) has announced the development of a ground-breaking new app to help improve workplaces, public buildings and homes for people living with dementia.
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Dementia Big
The University of Stirling’s Dementia Services Development Centre (DSDC) has announced the development of a ground-breaking new app to help improve workplaces, public buildings and homes for people living with dementia.
Dementia Big
Alzheimer’s Society is a proud partner of The Alzheimer’s Show and will be appearing at this year’s event in London on 9-10 June at Olympia.
Alzheimer’s Society is a proud partner of The Alzheimer’s Show and will be appearing at this year’s event in London on 9-10 June at Olympia.
(HealthDay)—For Marilyn and Tom Oestreicher, their golden years were within reach.
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The role of microglial cells in neurodegenerative disease is not fully understood. But new results from researchers in Munich and Basel suggest that stimulation of this arm of the immune system might well delay the onset of such disorders.
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Dementia Big
(HealthDay)—For Marilyn and Tom Oestreicher, their golden years were within reach.
Dementia Big
The role of microglial cells in neurodegenerative disease is not fully understood. But new results from researchers in Munich and Basel suggest that stimulation of this arm of the immune system might well delay the onset of such disorders.
A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer’s disease supports further investigation of its potential.
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A new study conducted by researchers from Tulane University finds reducing target systolic blood pressure below current recommendations significantly reduces the risk of cardiovascular disease and preventable death.
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A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer’s disease supports further investigation of its potential. Results of the four-week trial of scyllo-inositol, also known as ELND005, have been published in the Journal of Alzheimer’s Disease.
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Just as trimming back the branches of an overgrown plant can encourage healthy growth, a little pruning of the connections in the human brain can be a good thing during brain development. But what happens when this natural process goes wrong later in life? Investigators at Brigham and Women’s Hospital have found new clues from preclinical models to indicate that this “synaptic refinement” may play a role in neurodegenerative disease. Their findings, published in Science Translational Medicine, offer new insights into the interplay between the immune system and the development of Alzheimer’s disease.
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Dementia Big
A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer’s disease supports further investigation of its potential.
Dementia Big
A new study conducted by researchers from Tulane University finds reducing target systolic blood pressure below current recommendations significantly reduces the risk of cardiovascular disease and preventable death.
Dementia Big
A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer’s disease supports further investigation of its potential. Results of the four-week trial of scyllo-inositol, also known as ELND005, have been published in the Journal of Alzheimer’s Disease.
Dementia Big
Just as trimming back the branches of an overgrown plant can encourage healthy growth, a little pruning of the connections in the human brain can be a good thing during brain development. But what happens when this natural process goes wrong later in life? Investigators at Brigham and Women’s Hospital have found new clues from preclinical models to indicate that this “synaptic refinement” may play a role in neurodegenerative disease. Their findings, published in Science Translational Medicine, offer new insights into the interplay between the immune system and the development of Alzheimer’s disease.
