Wednesday, October 18, 2017

One step closer toward a treatment for Alzheimer's disease?

Scientists at the Massachusetts General Hospital (MGH), in collaboration with colleagues at the University California, San Diego (UCSD), have characterized a new class of drugs as potential therapeutics for Alzheimer’s disease and discovered a piece in the puzzle of how they would work. Their study, using disease-related animal and cellular models, shows that treatment with a representative compound of this class of gamma-secretase modulators leads to a reduction of the Alzheimer’s-associated beta-amyloid. The study has been online published in EBioMedicine, an open-access journal jointly published by Cell Press and The Lancet.

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