Monday, February 29, 2016

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

Using a drug compound created to treat cancer, University of California, Irvine neurobiologists have disarmed the brain’s response to the distinctive beta-amyloid plaques that are the hallmark of Alzheimer’s disease.

from Dementia Big http://ift.tt/1TN9T1r via alcoholic dementia


http://ift.tt/1TNnCW9

Are we ageing healthily? An interview with Professor Carol Jagger

This is the million dollar question but it is hard to give a definite answer. Most data on trends in life and healthy life expectancy use surveys that do not include people in care homes which can skew results at older ages.

from Dementia Big http://ift.tt/1Lqnjh8 via alcoholic dementia


http://ift.tt/1OJF8mf

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease:

Dementia Big
Using a drug compound created to treat cancer, University of California, Irvine neurobiologists have disarmed the brain’s response to the distinctive beta-amyloid plaques that are the hallmark of Alzheimer’s disease.


http://ift.tt/1T4HC6y

Are we ageing healthily? An interview with Professor Carol Jagger

Are we ageing healthily? An interview with Professor Carol Jagger:

Dementia Big
This is the million dollar question but it is hard to give a definite answer. Most data on trends in life and healthy life expectancy use surveys that do not include people in care homes which can skew results at older ages.


http://ift.tt/1LQW6iP

Blocking inflammation prevents cell death, improves memory in Alzheimer’s disease

Using a drug compound created to treat cancer, University of California, Irvine neurobiologists have disarmed the brain’s response to the distinctive beta-amyloid plaques that are the hallmark of Alzheimer’s disease.

from Dementia Big http://ift.tt/1TN9T1r
via Stopping Dementia



from WordPress http://ift.tt/1KZFKcJ
via alcoholic dementia
http://ift.tt/1T4HAvn

Are we ageing healthily? An interview with Professor Carol Jagger

This is the million dollar question but it is hard to give a definite answer. Most data on trends in life and healthy life expectancy use surveys that do not include people in care homes which can skew results at older ages.

from Dementia Big http://ift.tt/1Lqnjh8
via Stopping Dementia



from WordPress http://ift.tt/1RBq52r
via alcoholic dementia
http://ift.tt/1LQW3U5

Saturday, February 27, 2016

Novel therapeutic approach to target monomeric Tau protein

Novel therapeutic approach to target monomeric Tau protein:

Dementia Big
Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.


http://ift.tt/21qQ9FC

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

Researchers find way to inhibit enzyme responsible for Alzheimer's disease:

Dementia Big
For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer’s patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.


http://ift.tt/1oPiZyj

Researchers find way to inhibit enzyme responsible for Alzheimer’s disease

For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer’s patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.

from Dementia Big http://ift.tt/1QCVcHP
via Stopping Dementia



from WordPress http://ift.tt/21qOgZJ
via alcoholic dementia
http://ift.tt/1VKMDip

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

from Dementia Big http://ift.tt/1WPWTGw
via Stopping Dementia



from WordPress http://ift.tt/1RaZff0
via alcoholic dementia
http://ift.tt/1oPiYKO

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

from Dementia Big http://ift.tt/1WPWTGw via alcoholic dementia


http://ift.tt/1S8SOxL

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer’s patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.

from Dementia Big http://ift.tt/1QCVcHP via alcoholic dementia


http://ift.tt/1VKLFmi

Friday, February 26, 2016

Is dementia on the decline? Research suggests it might be

Is dementia on the decline? Research suggests it might be:

Dementia Big
Despite fears that the coming silver tsunami will trigger a dementia epidemic, a surprising new study suggests that it may be possible to delay - or even prevent - some kinds of dementia.


http://ift.tt/1UpRTcV

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels:

Dementia Big
Epidemiologic studies have demonstrated an association between diabetes and dementia. Insulin signaling within the brain, in particular within the hypothalamus regulates carbohydrate, lipid, and branched chain amino acid (BCAA) metabolism in peripheral organs such as the liver and adipose tissue. We hypothesized that cerebral amyloidosis impairs central nervous system control of metabolism through disruption of insulin signaling in the hypothalamus, which dysregulates glucose and BCAA homeostasis resulting in increased susceptibility to diabetes.


http://ift.tt/1QCOukW

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease:

Dementia Big
Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.


http://ift.tt/1UpRTcR

Is dementia on the decline? Research suggests it might be

Despite fears that the coming silver tsunami will trigger a dementia epidemic, a surprising new study suggests that it may be possible to delay – or even prevent – some kinds of dementia.

from Dementia Big http://ift.tt/21xc1fg
via Stopping Dementia



from WordPress http://ift.tt/1TJnrej
via alcoholic dementia
http://ift.tt/1TJnWVP

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer’s disease

Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

from Dementia Big http://ift.tt/1oMWCJN
via Stopping Dementia



from WordPress http://ift.tt/2113fUp
via alcoholic dementia
http://ift.tt/21149Ai

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer’s disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels

Epidemiologic studies have demonstrated an association between diabetes and dementia. Insulin signaling within the brain, in particular within the hypothalamus regulates carbohydrate, lipid, and branched chain amino acid (BCAA) metabolism in peripheral organs such as the liver and adipose tissue. We hypothesized that cerebral amyloidosis impairs central nervous system control of metabolism through disruption of insulin signaling in the hypothalamus, which dysregulates glucose and BCAA homeostasis resulting in increased susceptibility to diabetes.

from Dementia Big http://ift.tt/1UpAgK4
via Stopping Dementia



from WordPress http://ift.tt/1TJnref
via alcoholic dementia
http://ift.tt/1TJnUxb

Is dementia on the decline? Research suggests it might be

Despite fears that the coming silver tsunami will trigger a dementia epidemic, a surprising new study suggests that it may be possible to delay - or even prevent - some kinds of dementia.

from Dementia Big http://ift.tt/21xc1fg via alcoholic dementia


http://ift.tt/1Qjj8UF

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels

Epidemiologic studies have demonstrated an association between diabetes and dementia. Insulin signaling within the brain, in particular within the hypothalamus regulates carbohydrate, lipid, and branched chain amino acid (BCAA) metabolism in peripheral organs such as the liver and adipose tissue. We hypothesized that cerebral amyloidosis impairs central nervous system control of metabolism through disruption of insulin signaling in the hypothalamus, which dysregulates glucose and BCAA homeostasis resulting in increased susceptibility to diabetes.

from Dementia Big http://ift.tt/1UpAgK4 via alcoholic dementia


http://ift.tt/2113fnA

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

Dementia and other tauopathies, most notably Alzheimer’s disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

from Dementia Big http://ift.tt/1oMWCJN via alcoholic dementia


http://ift.tt/1Qjj8Eh

Pathoconnectomics of cognitive impairment in small vessel disease: A systematic review

Pathoconnectomics of cognitive impairment in small vessel disease: A systematic review:

Dementia Big
Cerebral small vessel disease (CSVD) is a highly prevalent condition associated with diffuse ischemic damage and cognitive dysfunction particularly in executive function and attention. Functional brain imaging studies can reveal mechanisms of cognitive impairment in CSVD, although findings are mixed.


http://ift.tt/1KPNVbB

Pathoconnectomics of cognitive impairment in small vessel disease: A systematic review

Cerebral small vessel disease (CSVD) is a highly prevalent condition associated with diffuse ischemic damage and cognitive dysfunction particularly in executive function and attention. Functional brain imaging studies can reveal mechanisms of cognitive impairment in CSVD, although findings are mixed.

from Dementia Big http://ift.tt/1KP61ub via alcoholic dementia


http://ift.tt/1OzTx4r

Pathoconnectomics of cognitive impairment in small vessel disease: A systematic review

Cerebral small vessel disease (CSVD) is a highly prevalent condition associated with diffuse ischemic damage and cognitive dysfunction particularly in executive function and attention. Functional brain imaging studies can reveal mechanisms of cognitive impairment in CSVD, although findings are mixed.

from Dementia Big http://ift.tt/1KP61ub
via Stopping Dementia



from WordPress http://ift.tt/1TCMMW8
via alcoholic dementia
http://ift.tt/1KPMnhQ

Thursday, February 25, 2016

Team suppresses oxidative stress and neuronal death associated with Alzheimer's disease

Team suppresses oxidative stress and neuronal death associated with Alzheimer's disease:

Dementia Big
The brain  is an enormous network of communication, containing over 100 billion nerve cells, or neurons, with branches that connect at more than 100 trillion points. They are constantly sending signals through a vast neuron forest that forms memories, thoughts and feelings; these patterns of activity form the essence of each person. Alzheimer’s disease (AD) disrupts both the way electrical charges travel within cells and the activity of neurotransmitters. An AD brain has fewer nerve cells and synapses than a healthy brain; plaques and abnormal clusters of protein fragments accumulate between nerve cells. The major pathological indicators of AD are the accumulation of amyloid beta plaques and neurofibrillary tangles in the brain. The pathways in our neuron forest are systemically attacked and destroyed by amyloid beta (Aβ): a solitary molecule that evolves into plaque clusters, which block cell-to-cell signalling at synapses. They may also activate immune system cells that result in inflammation and destroy damaged cells.


http://ift.tt/1oKnpXi

MOOCs: the future of healthcare training? An interview with David Robertshaw

MOOCs: the future of healthcare training? An interview with David Robertshaw:

Dementia Big
MOOCs are short, free courses run by major learning providers to share their knowledge of a particular academic topic or to help students develop a specific skill.


http://ift.tt/1Q4GoV5

Researchers work to block harmful behavior of key Alzheimer's enzyme

Researchers work to block harmful behavior of key Alzheimer's enzyme:

Dementia Big
Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer’s disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. A study appearing February 25 in Cell Reports presents a new therapeutic strategy: blocking the most harmful behavior enzyme while allowing it to work normally otherwise. This potential approach now needs to be further developed and tested in pre-clinical trials.


http://ift.tt/1oKnpXc

Active mind may delay symptoms of Alzheimer's disease, but not underlying brain changes

Active mind may delay symptoms of Alzheimer's disease, but not underlying brain changes:

Dementia Big
Keeping the mind active may delay symptoms of Alzheimer’s disease; however, the activity does not change the underlying disease in the brain for most people, according to a study published today in the online edition of Neurology, the medical journal of the American Academy of Neurology.


http://ift.tt/1Q4GoV0

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients:

Dementia Big
Many patients showing signs of dementia are quickly diagnosed with Alzheimer’s disease when they might actually suffer from frontotemporal dementia, delaying the appropriate treatment for them.


http://ift.tt/1oKnpXa

Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment

Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment:

Dementia Big
We evaluated the effect of Alzheimer’s disease (AD) susceptibility loci on endophenotypes closely related with AD pathology in patients with mild cognitive impairment (MCI).


http://ift.tt/1Q4GmfX

Researchers work to block harmful behavior of key Alzheimer’s enzyme

Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer’s disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. A study appearing February 25 in Cell Reports presents a new therapeutic strategy: blocking the most harmful behavior enzyme while allowing it to work normally otherwise. This potential approach now needs to be further developed and tested in pre-clinical trials.

from Dementia Big http://ift.tt/1R4ueJx
via Stopping Dementia



from WordPress http://ift.tt/1Q4D9wV
via alcoholic dementia
http://ift.tt/1oKnpX6

Researchers work to block harmful behavior of key Alzheimer's enzyme

Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer’s disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. A study appearing February 25 in Cell Reports presents a new therapeutic strategy: blocking the most harmful behavior enzyme while allowing it to work normally otherwise. This potential approach now needs to be further developed and tested in pre-clinical trials.

from Dementia Big http://ift.tt/1R4ueJx via alcoholic dementia


http://ift.tt/1KO220Q

MOOCs: the future of healthcare training? An interview with David Robertshaw

MOOCs are short, free courses run by major learning providers to share their knowledge of a particular academic topic or to help students develop a specific skill.

from Dementia Big http://ift.tt/1p8aBtN via alcoholic dementia


http://ift.tt/1WLHxmd

Active mind may delay symptoms of Alzheimer's disease, but not underlying brain changes

Keeping the mind active may delay symptoms of Alzheimer’s disease; however, the activity does not change the underlying disease in the brain for most people, according to a study published today in the online edition of Neurology, the medical journal of the American Academy of Neurology.

from Dementia Big http://ift.tt/1QGmaED via alcoholic dementia


http://ift.tt/1KO1YOQ

Team suppresses oxidative stress and neuronal death associated with Alzheimer’s disease

The brain  is an enormous network of communication, containing over 100 billion nerve cells, or neurons, with branches that connect at more than 100 trillion points. They are constantly sending signals through a vast neuron forest that forms memories, thoughts and feelings; these patterns of activity form the essence of each person. Alzheimer’s disease (AD) disrupts both the way electrical charges travel within cells and the activity of neurotransmitters. An AD brain has fewer nerve cells and synapses than a healthy brain; plaques and abnormal clusters of protein fragments accumulate between nerve cells. The major pathological indicators of AD are the accumulation of amyloid beta plaques and neurofibrillary tangles in the brain. The pathways in our neuron forest are systemically attacked and destroyed by amyloid beta (Aβ): a solitary molecule that evolves into plaque clusters, which block cell-to-cell signalling at synapses. They may also activate immune system cells that result in inflammation and destroy damaged cells.

from Dementia Big http://ift.tt/1oJFhSc
via Stopping Dementia



from WordPress http://ift.tt/1Q4D9gs
via alcoholic dementia
http://ift.tt/1WLHyXr

MOOCs: the future of healthcare training? An interview with David Robertshaw

MOOCs are short, free courses run by major learning providers to share their knowledge of a particular academic topic or to help students develop a specific skill.

from Dementia Big http://ift.tt/1p8aBtN
via Stopping Dementia



from WordPress http://ift.tt/1TBc0Ej
via alcoholic dementia
http://ift.tt/1KO1YOL

Team suppresses oxidative stress and neuronal death associated with Alzheimer's disease

The brain  is an enormous network of communication, containing over 100 billion nerve cells, or neurons, with branches that connect at more than 100 trillion points. They are constantly sending signals through a vast neuron forest that forms memories, thoughts and feelings; these patterns of activity form the essence of each person. Alzheimer’s disease (AD) disrupts both the way electrical charges travel within cells and the activity of neurotransmitters. An AD brain has fewer nerve cells and synapses than a healthy brain; plaques and abnormal clusters of protein fragments accumulate between nerve cells. The major pathological indicators of AD are the accumulation of amyloid beta plaques and neurofibrillary tangles in the brain. The pathways in our neuron forest are systemically attacked and destroyed by amyloid beta (Aβ): a solitary molecule that evolves into plaque clusters, which block cell-to-cell signalling at synapses. They may also activate immune system cells that result in inflammation and destroy damaged cells.

from Dementia Big http://ift.tt/1oJFhSc via alcoholic dementia


http://ift.tt/1WLHwyQ

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients

Many patients showing signs of dementia are quickly diagnosed with Alzheimer’s disease when they might actually suffer from frontotemporal dementia, delaying the appropriate treatment for them.

from Dementia Big http://ift.tt/1p7jIe5 via alcoholic dementia


http://ift.tt/1KO1Yyi

Active mind may delay symptoms of Alzheimer’s disease, but not underlying brain changes

Keeping the mind active may delay symptoms of Alzheimer’s disease; however, the activity does not change the underlying disease in the brain for most people, according to a study published today in the online edition of Neurology, the medical journal of the American Academy of Neurology.

from Dementia Big http://ift.tt/1QGmaED
via Stopping Dementia



from WordPress http://ift.tt/1Q4D9go
via alcoholic dementia
http://ift.tt/1WLHwyC

Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment

We evaluated the effect of Alzheimer’s disease (AD) susceptibility loci on endophenotypes closely related with AD pathology in patients with mild cognitive impairment (MCI).

from Dementia Big http://ift.tt/1p64bLq via alcoholic dementia


http://ift.tt/1KO21dv

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients

Many patients showing signs of dementia are quickly diagnosed with Alzheimer’s disease when they might actually suffer from frontotemporal dementia, delaying the appropriate treatment for them.

from Dementia Big http://ift.tt/1p7jIe5
via Stopping Dementia



from WordPress http://ift.tt/1TBc0Ef
via alcoholic dementia
http://ift.tt/1WLHyqp

Alzheimer’s disease risk variants modulate endophenotypes in mild cognitive impairment

We evaluated the effect of Alzheimer’s disease (AD) susceptibility loci on endophenotypes closely related with AD pathology in patients with mild cognitive impairment (MCI).

from Dementia Big http://ift.tt/1p64bLq
via Stopping Dementia



from WordPress http://ift.tt/1TBc32K
via alcoholic dementia
http://ift.tt/1KO1VCy

Wednesday, February 24, 2016

Immune cells may play greater role in Alzheimer's disease than originally thought

Immune cells may play greater role in Alzheimer's disease than originally thought:

Dementia Big
Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.


http://ift.tt/1Q1MWnt

People with dementia urged to consider volunteering for research studies

People with dementia urged to consider volunteering for research studies:

Dementia Big
People affected by dementia, particularly those in the early stages of the condition, are being urged to consider volunteering for research, to help vital new studies get off the ground.


http://ift.tt/24q2Dw7

Active mind, body may only do so much against Alzheimer's

Active mind, body may only do so much against Alzheimer's:

Dementia Big
(HealthDay)—There’s plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer’s disease. However, a new study shows those efforts may only go so far to keep dementia at bay.


http://ift.tt/1Q1MW6W

People with dementia urged to consider volunteering for research studies

People affected by dementia, particularly those in the early stages of the condition, are being urged to consider volunteering for research, to help vital new studies get off the ground.

from Dementia Big http://ift.tt/1TyLHhW via alcoholic dementia


http://ift.tt/24q2FnY

Active mind, body may only do so much against Alzheimer's

(HealthDay)—There’s plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer’s disease. However, a new study shows those efforts may only go so far to keep dementia at bay.

from Dementia Big http://ift.tt/1QdLWdO via alcoholic dementia


http://ift.tt/1Q1MTrG

Immune cells may play greater role in Alzheimer’s disease than originally thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

from Dementia Big http://ift.tt/21eZY9w
via Stopping Dementia



from WordPress http://ift.tt/1Rovo5e
via alcoholic dementia
http://ift.tt/1Qe6McV

People with dementia urged to consider volunteering for research studies

People affected by dementia, particularly those in the early stages of the condition, are being urged to consider volunteering for research, to help vital new studies get off the ground.

from Dementia Big http://ift.tt/1TyLHhW
via Stopping Dementia



from WordPress http://ift.tt/1T7TN2T
via alcoholic dementia
http://ift.tt/1T7TNjp

Active mind, body may only do so much against Alzheimer’s

(HealthDay)—There’s plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer’s disease. However, a new study shows those efforts may only go so far to keep dementia at bay.

from Dementia Big http://ift.tt/1QdLWdO
via Stopping Dementia



from WordPress http://ift.tt/1RovmKO
via alcoholic dementia
http://ift.tt/1Qe6Nh4

Immune cells may play greater role in Alzheimer's disease than originally thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

from Dementia Big http://ift.tt/21eZY9w via alcoholic dementia


http://ift.tt/1T7TNjd

Tuesday, February 23, 2016

Body's immune system may play larger role in Alzheimer's disease than thought

Body's immune system may play larger role in Alzheimer's disease than thought:

Dementia Big
Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.


http://ift.tt/20UfMsM

Body’s immune system may play larger role in Alzheimer’s disease than thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

from Dementia Big http://ift.tt/1KH0k1j
via Stopping Dementia



from WordPress http://ift.tt/1VDmX7n
via alcoholic dementia
http://ift.tt/1QCAE8w

Body's immune system may play larger role in Alzheimer's disease than thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer’s disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

from Dementia Big http://ift.tt/1KH0k1j via alcoholic dementia


http://ift.tt/1oGdjGT

Longitudinal decline in mild-to-moderate Alzheimer’s disease: Analyses of placebo data from clinical trials

Accurate estimates of cognitive and clinical decline rates are essential to the design of clinical trials in Alzheimer’s disease (AD) dementia.

from Dementia Big http://ift.tt/1oywIZC
via Stopping Dementia



from WordPress http://ift.tt/1VBnuGY
via alcoholic dementia
http://ift.tt/1T3LcOy

Longitudinal decline in mild-to-moderate Alzheimer's disease: Analyses of placebo data from clinical trials

Longitudinal decline in mild-to-moderate Alzheimer's disease: Analyses of placebo data from clinical trials:

Dementia Big
Accurate estimates of cognitive and clinical decline rates are essential to the design of clinical trials in Alzheimer’s disease (AD) dementia.


http://ift.tt/1Os8V2y

Longitudinal decline in mild-to-moderate Alzheimer's disease: Analyses of placebo data from clinical trials

Accurate estimates of cognitive and clinical decline rates are essential to the design of clinical trials in Alzheimer’s disease (AD) dementia.

from Dementia Big http://ift.tt/1oywIZC via alcoholic dementia


http://ift.tt/1KGDAyF

Monday, February 22, 2016

UCL researchers create first massive open online course on four less-common forms of dementia

Researchers at University College London have created the first massive open online course on four of the less-common forms of dementia. Developed by Timothy Shakespeare, with Sebastian Crutch and Nick Fox, “The Many Faces of Dementia” will kick off on March 14.

from Dementia Big http://ift.tt/1TzLo7N
via Stopping Dementia



from WordPress http://ift.tt/1RjCs3f
via alcoholic dementia
http://ift.tt/1Q7bbON

Antibody can give more precise information about Alzheimer’s disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.

from Dementia Big http://ift.tt/1LBRlJJ
via Stopping Dementia



from WordPress http://ift.tt/1L7rTkj
via alcoholic dementia
http://ift.tt/1KFEw68

UCL researchers create first massive open online course on four less-common forms of dementia

UCL researchers create first massive open online course on four less-common forms of dementia:

Dementia Big
Researchers at University College London have created the first massive open online course on four of the less-common forms of dementia. Developed by Timothy Shakespeare, with Sebastian Crutch and Nick Fox, “The Many Faces of Dementia” will kick off on March 14.


http://ift.tt/1SOOTqM

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers:

Dementia Big
For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.


http://ift.tt/1WF2xLr

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.

from Dementia Big http://ift.tt/1LBRlJJ via alcoholic dementia


http://ift.tt/1SOOTHt

UCL researchers create first massive open online course on four less-common forms of dementia

Researchers at University College London have created the first massive open online course on four of the less-common forms of dementia. Developed by Timothy Shakespeare, with Sebastian Crutch and Nick Fox, “The Many Faces of Dementia” will kick off on March 14.

from Dementia Big http://ift.tt/1TzLo7N via alcoholic dementia


http://ift.tt/1WF2xv2

Friday, February 19, 2016

Stem cell research reveals how Parkinson’s spreads from cell to cell

Stem cell research reveals how Parkinson’s spreads from cell to cell:

Dementia Big
Stem cell research published today offers up new clues as to how Parkinson’s spreads from cell to cell, a process which has evaded researchers for decades.


http://ift.tt/1OkwHxw

Antibody provide a more exact Alzheimer's diagnosis radioactive tracers

Antibody provide a more exact Alzheimer's diagnosis radioactive tracers:

Dementia Big
For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.


http://ift.tt/1QpXwrN

Antibody provide a more exact Alzheimer's diagnosis radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.

from Dementia Big http://ift.tt/1VrDwTQ via alcoholic dementia


http://ift.tt/1OkwFFP

Stem cell research reveals how Parkinson’s spreads from cell to cell

Stem cell research published today offers up new clues as to how Parkinson’s spreads from cell to cell, a process which has evaded researchers for decades.

from Dementia Big http://ift.tt/1os6uIc via alcoholic dementia


http://ift.tt/1OkwFFN

Stem cell research reveals how Parkinson’s spreads from cell to cell

Stem cell research published today offers up new clues as to how Parkinson’s spreads from cell to cell, a process which has evaded researchers for decades.

from Dementia Big http://ift.tt/1os6uIc
via Stopping Dementia



from WordPress http://ift.tt/1otqrhW
via alcoholic dementia
http://ift.tt/1QpXwrD

Antibody provide a more exact Alzheimer’s diagnosis radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.

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Thursday, February 18, 2016

Experimental drug candidate may aid traumatic brain injury patients

Experimental drug candidate may aid traumatic brain injury patients:

Dementia Big
A new report by University of Kentucky researcher Linda Van Eldik, PhD, describes an experimental drug candidate that may aid patients with traumatic brain injury (TBI).


http://ift.tt/1PJYCuP

Experimental drug candidate may aid traumatic brain injury patients

A new report by University of Kentucky researcher Linda Van Eldik, PhD, describes an experimental drug candidate that may aid patients with traumatic brain injury (TBI).

from Dementia Big http://ift.tt/1Q3RWcD via alcoholic dementia


http://ift.tt/212d8Xj

Experimental drug candidate may aid traumatic brain injury patients

A new report by University of Kentucky researcher Linda Van Eldik, PhD, describes an experimental drug candidate that may aid patients with traumatic brain injury (TBI).

from Dementia Big http://ift.tt/1Q3RWcD
via Stopping Dementia



from WordPress http://ift.tt/1Ubzssi
via alcoholic dementia
http://ift.tt/1Wv9dvv

Elizabeth MacKinlay and Corinne Trevitt, Facilitating spiritual reminiscence for people with dementia

Elizabeth MacKinlay and Corinne Trevitt, Facilitating spiritual reminiscence for people with dementia:

Dementia Big


http://ift.tt/1QNaDNT

A feasibility study of translating "Living Well with Dementia" groups into a Primary Care Improving Access to Psychological Therapy service (innovative practice)

A feasibility study of translating "Living Well with Dementia" groups into a Primary Care Improving Access to Psychological Therapy service (innovative practice): Dementia Big

This paper describes the use of the “Living Well with Dementia” or LivDem model of group support for people affected by dementia within a Primary Care setting. Five people affected by dementia and their carers joined a 10-week group, although one man withdrew before the start due to illness. Joint sessions were held on the first and the final meetings, with separate parallel group sessions for people affected by dementia and their carers for the remaining eight sessions. One person affected by dementia and their carer withdrew due to illness before the end of the sessions. A self-report measure of Quality of Life suggested improvements for two of the three people affected by dementia who completed all of the sessions. The proxy ratings of carers indicated improvements for all three participants. Qualitative interviews were carried out with participants and carers to assess their experience of the group. Although both people affected by dementia and their carers found the LivDem intervention helpful, concerns remain about the continued need for support by a Dementia specialist.


http://ift.tt/1SVvHIz

A methodological critique of the National Institute of Aging and Alzheimers Association Guidelines for Alzheimers disease, dementia, and mild cognitive impairments

A methodological critique of the National Institute of Aging and Alzheimers Association Guidelines for Alzheimers disease, dementia, and mild cognitive impairments: Dementia Big

In 2011, the U.S. National Institute on Aging published guidelines for clinical diagnostics for Alzheimer’s disease dementia. These guidelines define a continuum with three stages—an early, pre-clinical stage with no symptoms, followed by mild cognitive impairment, and a final stage of Alzheimer’s disease dementia. This methodological critique examines the validity of this continuum. No studies exist showing the progression of these biomarkers to Alzheimer’s disease. There is also a lack of empirical evidence showing how biomarkers determine mild cognitive impairment, which has multiple etiologies. The guidelines fail to explain anomalies where there are biomarkers but no expression of Alzheimer’s disease.


http://ift.tt/1QNaDNO

What are the experiences of people with dementia in employment?

What are the experiences of people with dementia in employment?: Dementia Big

Statistics show that an increase in the statutory retirement age in the UK will mean that many more people will develop a dementia while still in employment. A review of the literature confirmed that there are no existing studies in the UK which examine this issue in any detail. The aim of this study was to investigate the experiences of people who develop a dementia while still in employment and to understand how they make sense of these experiences; therefore a qualitative explorative inquiry based on an Interpretive Phenomenological Analysis methodology was used. Interviews with five people who had developed a dementia while still in employment were carried out, with ages ranging from 58 to 74 years. Interview transcripts were analysed and four super-ordinate themes were identified: the realization that something is wrong; managing the situation in the workplace; trying to make sense of change; and coming to terms with retirement or unemployment. The results showed that people who develop a dementia while still in employment do not always receive the ‘reasonable adjustments’ in the workplace to which they are entitled under the Equality Act (2010). Some of the participants felt that they were poorly treated by their workplace and described some distressing experiences. The study highlights the need for more effective specialized advice and support regarding employment issues and more research into the numbers of people in the UK that are affected by this issue.


http://ift.tt/1SVvHIv

Dementia RED (Respect Empathy Dignity): Collaborating to build dementia supportive communities in North Wales - reporting on a pilot project (innovative practice)

Dementia RED (Respect Empathy Dignity): Collaborating to build dementia supportive communities in North Wales - reporting on a pilot project (innovative practice): Dementia Big

There is increasing interest in developing dementia supportive communities world wide. Dementia RED (Respect Empathy Dignity) is a unique example from North Wales which is based on the twin concepts of people living with dementia as citizens in their community and developing ‘bottom up’ rather than ‘top down’ approaches to dementia supportive communities. Most people with dementia prefer to live at home thus making community connectivity key to maintaining healthy relationships and wellbeing. For those living with dementia, the community plays a pivotal role in providing value, meaning, purpose and acceptance. Building dementia supportive communities helps to raise awareness about dementia in the community through engagement and from identifying champions in the locality to voice issues. Dementia RED is an initiative and service which helps to develop such a philosophy in creating a dementia supportive community.


http://ift.tt/1QNaDNM

Structured interviews examining the burden, coping, self-efficacy, and quality of life among family caregivers of persons with dementia in Singapore

Structured interviews examining the burden, coping, self-efficacy, and quality of life among family caregivers of persons with dementia in Singapore: Dementia Big

Dementia is a global health issue and the effects on caregivers are substantial. The study aimed to examine the associations of burden, coping, self-efficacy with quality of life among family caregivers of persons with dementia in Singapore. Structured interviews were conducted in a convenience sample of 84 family caregivers caring and seeking clinical care for the persons with dementia in an outpatient clinic of a public hospital in Singapore. The outcome measures included the Family Burden Interview Schedule, Family Crisis Oriented Personal Evaluation Scale, General Perceived Self-Efficacy Scale, and World Health Organization Quality of Life Scale – Brief Version. In general, significant correlations were observed between the quality of life scores with coping strategy and family burden scores, but not between the coping strategy and family burden scores. Compared to demographic factors such as caregiver age and household income, psychosocial factors including family burden, coping strategies, and self-efficacy demonstrated greater association with quality of life in the participants. However, the dynamics of these associations will change with an increasing population of persons with dementia, decreasing nuclear family size, and predicted changes in family living arrangements for the persons with dementia in future. As such, it necessitates continuous study examining the needs and concerns of family caregivers and the relevance of ongoing interventions specific to caregivers of persons with dementia.


http://ift.tt/1SVvEMG

Caring for older people living alone with dementia: Healthcare professionals experiences

Caring for older people living alone with dementia: Healthcare professionals experiences: Dementia Big

Older adults living alone with dementia are at greater risk of placement in long-term care homes compared with those living with others. Healthcare professionals have vital roles in supporting them to continue living in the community. Yet, little is known about how healthcare professionals fulfill these roles and what their experiences are like. The study purpose was to describe health care professionals’ experiences of caring for older people with dementia living alone. Using a qualitative descriptive approach and qualitative content analysis method, 15 healthcare professionals were interviewed in Ontario, Canada. The overall theme of the findings, doing the best we can for them, involved discussing sensitive care issues with what professionals viewed as gentle realism. Walking the tightrope expressed tensions in meeting professional responsibilities. Constraints (my hands are tied) and boundaries (it’s not my job, it’s not my decision) described perceived limitations on professional roles. Effects of the emotional struggle involved in working with these older people were lessened by believing I did the right thing. The findings have implications for what we could do better for older people with dementia living alone, through integration of person-centered/relationship-centered principles in education programs, community agency policies, a national dementia care strategy, and culture change in community care.


http://ift.tt/1QNaDNK

Facilitating independence: The benefits of a post-diagnostic support project for people with dementia

Facilitating independence: The benefits of a post-diagnostic support project for people with dementia: Dementia Big

Providing support in the form of information, advice and access to services or social events is promoted as beneficial for people newly diagnosed with dementia and their families. This paper reports on key findings from an evaluation of a post-diagnostic support pilot project in Scotland addressing local service gaps, namely information provision, emotional and practical support and maintaining community links. Twenty-seven participants (14 people newly diagnosed with dementia and 13 family carers) were interviewed at two time points: T1 shortly after joining the pilot project and T2 approximately six months later, to ascertain their views on existing services and the support offered by the pilot project. A comparative thematic analysis revealed that the project facilitated increased independence (associated with increased motivation and self-confidence) of people with dementia. The project illustrates what can be achieved if resources are targeted at providing individualised post-diagnostic support, particularly where there are service delivery gaps.


http://ift.tt/1SVvEwl

Junior doctor dementia champions in a district general hospital (innovative practice)

Junior doctor dementia champions in a district general hospital (innovative practice): Dementia Big

Dementia is a common condition in the UK with around 25% of patients in acute hospitals having dementia. In the UK, there is national guidance on the assessment of cognitive impairment in acute hospitals. This article is a qualitative study of junior doctors’ experiences as part of a dementia and delirium team involved in changing the care of patients with dementia in a hospital in the UK. It draws on data from a focus group and follow-up questionnaire in two hospital trusts. We examine what drives doctors to become involved in such projects and the effects of this experience upon them. We suggest a typology for getting junior doctors involved in projects generating change when working with patients with dementia. Being more actively involved in caring for and developing services for patients with dementia may represent the crossing of an educational threshold for these junior doctors.


http://ift.tt/1QNaBWe

The paradox of dementia: Changes in assimilation after receiving a diagnosis of dementia

The paradox of dementia: Changes in assimilation after receiving a diagnosis of dementia: Dementia Big

This qualitative study used semi-structured interviews to explore how six people talked about their difficulties before and after a dementia diagnosis. Participants’ accounts of their memory problems were analysed in terms of the verbal Markers of Assimilation of Problematic Voices Scale. This analysis indicated that after diagnosis some participants were able to integrate aspects of their illness that had previously been too painful, and which had been warded off. The process by which individuals were able to integrate a dementia diagnosis into their sense of self-involved stepping in and out of awareness, with both acceptance and denial featuring in their accounts as they approached and then retreated from addressing the diagnosis. In contrast, other participants resisted moving towards explicitly acknowledging their dementia but were instead able to express concerns about what this movement would entail, for instance voicing their fears that it would mean that they had surrendered. Social support seems to have been crucial in enabling participants to sustain a positive sense of self in the face of this adjustment.


http://ift.tt/1SVvHs3

Eileen Eisner, Engaging and communicating with people who have dementia: Finding and using their strengths

Eileen Eisner, Engaging and communicating with people who have dementia: Finding and using their strengths: Dementia Big

Providing support in the form of information, advice and access to services or social events is promoted as beneficial for people newly diagnosed with dementia and their families. This paper reports on key findings from an evaluation of a post-diagnostic support pilot project in Scotland addressing local service gaps, namely information provision, emotional and practical support and maintaining community links. Twenty-seven participants (14 people newly diagnosed with dementia and 13 family carers) were interviewed at two time points: T1 shortly after joining the pilot project and T2 approximately six months later, to ascertain their views on existing services and the support offered by the pilot project. A comparative thematic analysis revealed that the project facilitated increased independence (associated with increased motivation and self-confidence) of people with dementia. The project illustrates what can be achieved if resources are targeted at providing individualised post-diagnostic support, particularly where there are service delivery gaps.


http://ift.tt/1QNaBW8

Editorial: Innovative practice

Editorial: Innovative practice: Dementia Big

Providing support in the form of information, advice and access to services or social events is promoted as beneficial for people newly diagnosed with dementia and their families. This paper reports on key findings from an evaluation of a post-diagnostic support pilot project in Scotland addressing local service gaps, namely information provision, emotional and practical support and maintaining community links. Twenty-seven participants (14 people newly diagnosed with dementia and 13 family carers) were interviewed at two time points: T1 shortly after joining the pilot project and T2 approximately six months later, to ascertain their views on existing services and the support offered by the pilot project. A comparative thematic analysis revealed that the project facilitated increased independence (associated with increased motivation and self-confidence) of people with dementia. The project illustrates what can be achieved if resources are targeted at providing individualised post-diagnostic support, particularly where there are service delivery gaps.


http://ift.tt/1SVvEw9

Elizabeth MacKinlay and Corinne Trevitt, Facilitating spiritual reminiscence for people with dementia

from Dementia Big http://ift.tt/1KtzKZE
via Stopping Dementia



from WordPress http://ift.tt/1OiUcHg
via alcoholic dementia
http://ift.tt/1SVvHrZ

A feasibility study of translating “Living Well with Dementia” groups into a Primary Care Improving Access to Psychological Therapy service (innovative practice)

This paper describes the use of the “Living Well with Dementia” or LivDem model of group support for people affected by dementia within a Primary Care setting. Five people affected by dementia and their carers joined a 10-week group, although one man withdrew before the start due to illness. Joint sessions were held on the first and the final meetings, with separate parallel group sessions for people affected by dementia and their carers for the remaining eight sessions. One person affected by dementia and their carer withdrew due to illness before the end of the sessions. A self-report measure of Quality of Life suggested improvements for two of the three people affected by dementia who completed all of the sessions. The proxy ratings of carers indicated improvements for all three participants. Qualitative interviews were carried out with participants and carers to assess their experience of the group. Although both people affected by dementia and their carers found the LivDem intervention helpful, concerns remain about the continued need for support by a Dementia specialist.

from Dementia Big http://ift.tt/1KtzKJ8
via Stopping Dementia



from WordPress http://ift.tt/1OiUcac
via alcoholic dementia
http://ift.tt/1QNaASa

Caring for older people living alone with dementia: Healthcare professionals experiences

Older adults living alone with dementia are at greater risk of placement in long-term care homes compared with those living with others. Healthcare professionals have vital roles in supporting them to continue living in the community. Yet, little is known about how healthcare professionals fulfill these roles and what their experiences are like. The study purpose was to describe health care professionals’ experiences of caring for older people with dementia living alone. Using a qualitative descriptive approach and qualitative content analysis method, 15 healthcare professionals were interviewed in Ontario, Canada. The overall theme of the findings, doing the best we can for them, involved discussing sensitive care issues with what professionals viewed as gentle realism. Walking the tightrope expressed tensions in meeting professional responsibilities. Constraints (my hands are tied) and boundaries (it’s not my job, it’s not my decision) described perceived limitations on professional roles. Effects of the emotional struggle involved in working with these older people were lessened by believing I did the right thing. The findings have implications for what we could do better for older people with dementia living alone, through integration of person-centered/relationship-centered principles in education programs, community agency policies, a national dementia care strategy, and culture change in community care.

from Dementia Big http://ift.tt/1Vr7Z4a
via Stopping Dementia



from WordPress http://ift.tt/1KtAxcP
via alcoholic dementia
http://ift.tt/1SVvEfK

A methodological critique of the National Institute of Aging and Alzheimers Association Guidelines for Alzheimers disease, dementia, and mild cognitive impairments

In 2011, the U.S. National Institute on Aging published guidelines for clinical diagnostics for Alzheimer’s disease dementia. These guidelines define a continuum with three stages—an early, pre-clinical stage with no symptoms, followed by mild cognitive impairment, and a final stage of Alzheimer’s disease dementia. This methodological critique examines the validity of this continuum. No studies exist showing the progression of these biomarkers to Alzheimer’s disease. There is also a lack of empirical evidence showing how biomarkers determine mild cognitive impairment, which has multiple etiologies. The guidelines fail to explain anomalies where there are biomarkers but no expression of Alzheimer’s disease.

from Dementia Big http://ift.tt/1Vr7Z4q
via Stopping Dementia



from WordPress http://ift.tt/1KtAxcR
via alcoholic dementia
http://ift.tt/1SVvHbv

Structured interviews examining the burden, coping, self-efficacy, and quality of life among family caregivers of persons with dementia in Singapore

Dementia is a global health issue and the effects on caregivers are substantial. The study aimed to examine the associations of burden, coping, self-efficacy with quality of life among family caregivers of persons with dementia in Singapore. Structured interviews were conducted in a convenience sample of 84 family caregivers caring and seeking clinical care for the persons with dementia in an outpatient clinic of a public hospital in Singapore. The outcome measures included the Family Burden Interview Schedule, Family Crisis Oriented Personal Evaluation Scale, General Perceived Self-Efficacy Scale, and World Health Organization Quality of Life Scale – Brief Version. In general, significant correlations were observed between the quality of life scores with coping strategy and family burden scores, but not between the coping strategy and family burden scores. Compared to demographic factors such as caregiver age and household income, psychosocial factors including family burden, coping strategies, and self-efficacy demonstrated greater association with quality of life in the participants. However, the dynamics of these associations will change with an increasing population of persons with dementia, decreasing nuclear family size, and predicted changes in family living arrangements for the persons with dementia in future. As such, it necessitates continuous study examining the needs and concerns of family caregivers and the relevance of ongoing interventions specific to caregivers of persons with dementia.

from Dementia Big http://ift.tt/1Vr7YgR
via Stopping Dementia



from WordPress http://ift.tt/1KtAzkZ
via alcoholic dementia
http://ift.tt/1QNaBFH

Dementia RED (Respect Empathy Dignity): Collaborating to build dementia supportive communities in North Wales – reporting on a pilot project (innovative practice)

There is increasing interest in developing dementia supportive communities world wide. Dementia RED (Respect Empathy Dignity) is a unique example from North Wales which is based on the twin concepts of people living with dementia as citizens in their community and developing ‘bottom up’ rather than ‘top down’ approaches to dementia supportive communities. Most people with dementia prefer to live at home thus making community connectivity key to maintaining healthy relationships and wellbeing. For those living with dementia, the community plays a pivotal role in providing value, meaning, purpose and acceptance. Building dementia supportive communities helps to raise awareness about dementia in the community through engagement and from identifying champions in the locality to voice issues. Dementia RED is an initiative and service which helps to develop such a philosophy in creating a dementia supportive community.

from Dementia Big http://ift.tt/1KtzKIY
via Stopping Dementia



from WordPress http://ift.tt/1OiUca6
via alcoholic dementia
http://ift.tt/1QNaABR

What are the experiences of people with dementia in employment?

The paradox of dementia: Changes in assimilation after receiving a diagnosis of dementia

This qualitative study used semi-structured interviews to explore how six people talked about their difficulties before and after a dementia diagnosis. Participants’ accounts of their memory problems were analysed in terms of the verbal Markers of Assimilation of Problematic Voices Scale. This analysis indicated that after diagnosis some participants were able to integrate aspects of their illness that had previously been too painful, and which had been warded off. The process by which individuals were able to integrate a dementia diagnosis into their sense of self-involved stepping in and out of awareness, with both acceptance and denial featuring in their accounts as they approached and then retreated from addressing the diagnosis. In contrast, other participants resisted moving towards explicitly acknowledging their dementia but were instead able to express concerns about what this movement would entail, for instance voicing their fears that it would mean that they had surrendered. Social support seems to have been crucial in enabling participants to sustain a positive sense of self in the face of this adjustment.

from Dementia Big http://ift.tt/1Vr7Y0j
via Stopping Dementia



from WordPress http://ift.tt/1KtAzkX
via alcoholic dementia
http://ift.tt/1SVvDZf

Study explores link between CSF biomarkers and cognition in Parkinson's disease

Study explores link between CSF biomarkers and cognition in Parkinson's disease:

Dementia Big
Many patients with Parkinson’s Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research published in the Journal of Parkinson’s Disease indicates that lower concentrations of α-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.


http://ift.tt/1Ua3QDh

Eating one portion of fish a week helps reduce dementia risk

Eating one portion of fish a week helps reduce dementia risk:

Dementia Big
Eating at least one portion of fish per week helps to reduce a person’s risk of developing Alzheimer’s disease and dementia-related illnesses. This was evidenced by international research conducted at the Rush University Medical Center in Chicago and published in the Journal of American Medical Association (JAMA).


http://ift.tt/1QnYZIH

Impact of interventions to reduce Alzheimer disease pathology on the prevalence of dementia in the oldest-old

Impact of interventions to reduce Alzheimer disease pathology on the prevalence of dementia in the oldest-old:

Dementia Big
The number of persons aged >90 years will grow significantly in coming decades. This group has the highest rates of dementia, most commonly Alzheimer’s disease (AD).


http://ift.tt/1Ua3NYn

Study explores link between CSF biomarkers and cognition in Parkinson's disease

Many patients with Parkinson’s Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research published in the Journal of Parkinson’s Disease indicates that lower concentrations of α-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.

from Dementia Big http://ift.tt/1PSESTU via alcoholic dementia


http://ift.tt/1QnYX3B

Eating one portion of fish a week helps reduce dementia risk

Eating at least one portion of fish per week helps to reduce a person’s risk of developing Alzheimer’s disease and dementia-related illnesses. This was evidenced by international research conducted at the Rush University Medical Center in Chicago and published in the Journal of American Medical Association (JAMA).

from Dementia Big http://ift.tt/1Wt0aez via alcoholic dementia


http://ift.tt/1Ua3NHJ

Impact of interventions to reduce Alzheimer disease pathology on the prevalence of dementia in the oldest-old

The number of persons aged >90 years will grow significantly in coming decades. This group has the highest rates of dementia, most commonly Alzheimer’s disease (AD).

from Dementia Big http://ift.tt/1ROWTan via alcoholic dementia


http://ift.tt/1QnYWMZ

Study explores link between CSF biomarkers and cognition in Parkinson’s disease

Many patients with Parkinson’s Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research published in the Journal of Parkinson’s Disease indicates that lower concentrations of α-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.

from Dementia Big http://ift.tt/1PSESTU
via Stopping Dementia



from WordPress http://ift.tt/1QmGlXW
via alcoholic dementia
http://ift.tt/1QmGmeF

Eating one portion of fish a week helps reduce dementia risk

Eating at least one portion of fish per week helps to reduce a person’s risk of developing Alzheimer’s disease and dementia-related illnesses. This was evidenced by international research conducted at the Rush University Medical Center in Chicago and published in the Journal of American Medical Association (JAMA).

from Dementia Big http://ift.tt/1Wt0aez
via Stopping Dementia



from WordPress http://ift.tt/1R9JIhS
via alcoholic dementia
http://ift.tt/21aGCz4

Impact of interventions to reduce Alzheimer disease pathology on the prevalence of dementia in the oldest-old

The number of persons aged >90 years will grow significantly in coming decades. This group has the highest rates of dementia, most commonly Alzheimer’s disease (AD).

from Dementia Big http://ift.tt/1ROWTan
via Stopping Dementia



from WordPress http://ift.tt/1QmGj2s
via alcoholic dementia
http://ift.tt/1QmGmew

Wednesday, February 17, 2016

First-of-its-kind project focuses on farming communities and dementia

First-of-its-kind project focuses on farming communities and dementia:

Dementia Big
Dementia is a growing health problem, with an anticipated increase in the number of cases in the UK of 156 per cent between now and 2051, according to statistics from the Alzheimer’s Society.


http://ift.tt/1QlBOoQ

Better understanding link between oral bacteria and certain types of stroke

Better understanding link between oral bacteria and certain types of stroke:

Dementia Big
In a study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria (cnm-positive Streptococcus mutans).


http://ift.tt/1PRrM9g

Family found with unusually heritable Alzheimer's risk

Family found with unusually heritable Alzheimer's risk:

Dementia Big
More than a decade ago, a woman in her early 70s came to see neurologist Allan Levey for an evaluation. She was experiencing progressive memory decline and was there with her children.


http://ift.tt/1QlBLt2

Better understanding link between oral bacteria and certain types of stroke

In a study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria (cnm-positive Streptococcus mutans).

from Dementia Big http://ift.tt/1KpiN2m
via Stopping Dementia



from WordPress http://ift.tt/1Q24UHN
via alcoholic dementia
http://ift.tt/1Lu6SLB

First-of-its-kind project focuses on farming communities and dementia

Dementia is a growing health problem, with an anticipated increase in the number of cases in the UK of 156 per cent between now and 2051, according to statistics from the Alzheimer’s Society.

from Dementia Big http://ift.tt/1U7Dwd1 via alcoholic dementia


http://ift.tt/1Lu6VqA

Better understanding link between oral bacteria and certain types of stroke

In a study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria (cnm-positive Streptococcus mutans).

from Dementia Big http://ift.tt/1KpiN2m via alcoholic dementia


http://ift.tt/1oKOdXc

Family found with unusually heritable Alzheimer's risk

More than a decade ago, a woman in her early 70s came to see neurologist Allan Levey for an evaluation. She was experiencing progressive memory decline and was there with her children.

from Dementia Big http://ift.tt/1PF60HU via alcoholic dementia


http://ift.tt/1Lu6SLx

Tuesday, February 16, 2016

Researchers highlight brain region as 'ground zero' of Alzheimer's disease

Researchers highlight brain region as 'ground zero' of Alzheimer's disease:

Dementia Big
A critical but vulnerable region in the brain appears to be the first place affected by late onset Alzheimer’s disease and may be more important for maintaining cognitive function in later life than previously appreciated, according to a new review of the scientific literature.


http://ift.tt/1LsRnDG

Edward Jones commits $4.7 million to support mission of Alzheimer's Association

Edward Jones commits $4.7 million to support mission of Alzheimer's Association:

Dementia Big
The Alzheimer’s Association today announced an historic partnership with St. Louis-based financial services firm Edward Jones. Edward Jones has committed $4.7 million over two years to support the mission of the Alzheimer’s Association.


http://ift.tt/1LsRmzG

New project focuses on dementia in farming and rural communities

New project focuses on dementia in farming and rural communities:

Dementia Big
Dementia is a growing health problem, with an anticipated increase in the number of cases of 156 per cent between now and 2051, according to statistics from the Alzheimer’s Society.


http://ift.tt/1TpYq7Y

Edward Jones commits $4.7 million to support mission of Alzheimer’s Association

The Alzheimer’s Association today announced an historic partnership with St. Louis-based financial services firm Edward Jones. Edward Jones has committed $4.7 million over two years to support the mission of the Alzheimer’s Association.

from Dementia Big http://ift.tt/1KUeMCR
via Stopping Dementia



from WordPress http://ift.tt/1TpXjoJ
via alcoholic dementia
http://ift.tt/1TpYq7S

Researchers highlight brain region as ‘ground zero’ of Alzheimer’s disease

A critical but vulnerable region in the brain appears to be the first place affected by late onset Alzheimer’s disease and may be more important for maintaining cognitive function in later life than previously appreciated, according to a new review of the scientific literature.

from Dementia Big http://ift.tt/1LrNjDB
via Stopping Dementia



from WordPress http://ift.tt/1PPSfUH
via alcoholic dementia
http://ift.tt/1TpYq7O

New project focuses on dementia in farming and rural communities

Dementia is a growing health problem, with an anticipated increase in the number of cases of 156 per cent between now and 2051, according to statistics from the Alzheimer’s Society.

from Dementia Big http://ift.tt/1RJe1y9
via Stopping Dementia



from WordPress http://ift.tt/1PPSgYM
via alcoholic dementia
http://ift.tt/1LsRnDu

New project focuses on dementia in farming and rural communities

Dementia is a growing health problem, with an anticipated increase in the number of cases of 156 per cent between now and 2051, according to statistics from the Alzheimer’s Society.

from Dementia Big http://ift.tt/1RJe1y9 via alcoholic dementia


http://ift.tt/1TpYp3F

Researchers highlight brain region as 'ground zero' of Alzheimer's disease

A critical but vulnerable region in the brain appears to be the first place affected by late onset Alzheimer’s disease and may be more important for maintaining cognitive function in later life than previously appreciated, according to a new review of the scientific literature.

from Dementia Big http://ift.tt/1LrNjDB via alcoholic dementia


http://ift.tt/1LsRnn8

Edward Jones commits $4.7 million to support mission of Alzheimer's Association

The Alzheimer’s Association today announced an historic partnership with St. Louis-based financial services firm Edward Jones. Edward Jones has committed $4.7 million over two years to support the mission of the Alzheimer’s Association.

from Dementia Big http://ift.tt/1KUeMCR via alcoholic dementia


http://ift.tt/1TpYq7K

Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias

Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias:

Dementia Big
Aggregation of tau is a hallmark of many neurodegenerative diseases, and tau imaging with positron emission tomography (PET) may allow early diagnosis and treatment monitoring. We assessed binding of the PET tracer [18F]AV-1451 in a range of dementias.


http://ift.tt/1QjjmqH

Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer’s disease, primary tauopathies, and other dementias

Aggregation of tau is a hallmark of many neurodegenerative diseases, and tau imaging with positron emission tomography (PET) may allow early diagnosis and treatment monitoring. We assessed binding of the PET tracer [18F]AV-1451 in a range of dementias.

from Dementia Big http://ift.tt/1LqDx4K
via Stopping Dementia



from WordPress http://ift.tt/20B3Hsx
via alcoholic dementia
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Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias

Aggregation of tau is a hallmark of many neurodegenerative diseases, and tau imaging with positron emission tomography (PET) may allow early diagnosis and treatment monitoring. We assessed binding of the PET tracer [18F]AV-1451 in a range of dementias.

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Monday, February 15, 2016

University of Derby hosts Dementia Care conference

University of Derby hosts Dementia Care conference:

Dementia Big
The University of Derby is hosting a dementia conference to develop knowledge and understanding of dementia in the community and primary care.


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Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD

Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD:

Dementia Big
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders.


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University of Derby hosts Dementia Care conference

The University of Derby is hosting a dementia conference to develop knowledge and understanding of dementia in the community and primary care.

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Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders.

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Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders.

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University of Derby hosts Dementia Care conference

The University of Derby is hosting a dementia conference to develop knowledge and understanding of dementia in the community and primary care.

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Sunday, February 14, 2016

Caregiver Burnout Courses In Houston TX

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Can you like caregiver burnout to be a thing of the past for you personally?
Picture changing stress, with comfortable confidence; changing defeat, with creativity and clarity.
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Are you a health care professional who works with seniors? Does one function with Alzheimer’s dementia or memory loss sufferers?

I understand. The longer it goes if you’re like most health care providers later or sooner plus the more difficult it’s on you caregiver burn-out will probably be a recognizable term for you personally.
Actually if you’re not suffering from health care provider burnout? You like to feel better as a health professional would? Would you prefer for the seniors with to feel better you work? Might it profit them produce more originality, to better their memory and clarity?

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Imagine if I told you there is some easy ways that you may do all that plus it could take less than 20 minutes a day to you?
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Would you like healthcare professional burnout to be a matter of the past for you personally?
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Place down.
Can you sense an in your brow,
the beginnings of a head ache,
maybe some pressure factors on your own brow?
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this program that creates new neural pathways. That is invaluable for you personally and for
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Caregiver Burnout Resources In Houston TX

https://www.youtube.com/watch?v=6xoJkHZ5M7U Caregiver burnout groups Houston TX My name is Houston and I would like to thank you for joining this short video called “An Answer to CAregiver Burnout” Caregiver Burnout Resources

Are you a health care professional who works with seniors? Would you work with storage loss patients, Alzheimer’s or dementia?

I understand. The longer it goes if you’re like the majority of health care providers ultimately and the more challenging it’s on you caregiver burn-out will soon be a recognizable phrase for you personally.
Actually if you’re not suffering from caregiver burnout? You like to feel better as a health professional would? Would you like for the seniors with to feel better you work? Would it profit them create more creativity, to boost their recollection and clearness?

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What if I told you there is some easy ways that one could do that all and it may take you less than 20 minutes a day?
Maybe not only for the seniors, but in addition yourself you work with.
Would you like caregiver burnout to be a thing of the past for you personally?
Imagine replacing stress, with comfortable trust; replacing defeat, with imagination and clarity.
How much more pleasing might your care-giving be, from using a software utilized reverse, stop, and to prevent most forms including Alzheimer’s, along with other forms of memory loss as that occurs normally.
Let us do a quick test if you could be actually helped by this program to find out.
Put down.
Would you sense an in your forehead,
the start of a headache,
Possibly some pressure points on your own forehead?
That allows you to realize you could profit from
this software that creates new neural pathways. This really is very useful for the seniors and for you personally
that you work with.

Visit http://ift.tt/1U9A4Nr for information on Caregiver Burnout Resources and Caregiver Burnout Groups Texas

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Stopping Dementia



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Caregiver Burnout Counselling In Houston TX

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Are you currently a health care provider who works with seniors? Do you function with memory loss patients, Alzheimer Disease or dementia?

I understand. The longer it goes if you are like the majority of health care providers ultimately plus the harder it’s on you health professional burn-out will soon be a recognizable phrase for you.
Actually if you are not suffering from health care provider burnout? You like to feel better, as a caregiver would? Would you want for the old persons with to feel better you work? Might it benefit them to enhance their recollection, create more ingenuity and clearness?

Caregiver Burnout Counselling In Houston TX

What if I told it could take less than 20 minutes a day to you plus you there is some easy ways you could do that all?
Maybe not only for yourself, but also the old persons you perform with.
Would you like caregiver burnout to be a matter of the past for you?
Imagine replacing pressure, with comfortable confidence; replacing defeat, with originality and clarity.
How much mo Re pleasurable would your care-giving be, as that occurs normally from employing a software used to avoid, stop, and reverse most kinds of Dementia, including Alzheimer Disease, and other kinds of loss.
Let us do a quick test if this software could actually assist you to determine.
Put your without doubt.
Would you sense in your forehead for a,
the beginnings of a head ache,
Possibly some anxiety points on your own forehead?
That allows you to understand that you might benefit from
this program that creates new neural pathways. This really is hardly useless for the seniors and for you
that you perform with.

Visit http://ift.tt/1U9A4Nr for information on Caregiver Burnout Counselling and Caregiver Burnout Groups Texas

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Saturday, February 13, 2016

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease:

Dementia Big
Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer’s disease, in a similar way to how statins are able to reduce the risk of developing heart disease.


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Dementia decline heralds hope of reduced burden

Dementia decline heralds hope of reduced burden:

Dementia Big
Analysis of participants in the Framingham Heart Study has shown a decline in dementia over a period of 3 decades.


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Poor physical fitness in middle age linked to smaller brain size 20 years later

Poor physical fitness in middle age linked to smaller brain size 20 years later:

Dementia Big
Poor physical fitness in middle age may be linked to a smaller brain size 20 years later, according to a study published in the February 10, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.


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Treatment gives hope to teen with disorder known as childhood Alzheimer's

Treatment gives hope to teen with disorder known as childhood Alzheimer's:

Dementia Big
The mother and father watched as their 16-year-old daughter ate her pork chop and green beans across the kitchen table of their Mount Prospect home, grateful each time she swallowed without struggle.


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Dementia decline heralds hope of reduced burden

Analysis of participants in the Framingham Heart Study has shown a decline in dementia over a period of 3 decades.

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Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer’s disease, in a similar way to how statins are able to reduce the risk of developing heart disease.

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