Memory training with unpredictable components could be more effective in enhancing episodic memory than training with predictable elements, according to new findings from UT Dallas researchers published in the journal Frontiers in Psychology.
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Many relatives and friends providing financial support or care to people with dementia have dipped into their retirement savings, cut back on spending and sold assets to pay for expenses tied to the disease, according to a survey released Wednesday by the Alzheimer’s Association.
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Dementia Big
Memory training with unpredictable components could be more effective in enhancing episodic memory than training with predictable elements, according to new findings from UT Dallas researchers published in the journal Frontiers in Psychology.
Dementia Big
Many relatives and friends providing financial support or care to people with dementia have dipped into their retirement savings, cut back on spending and sold assets to pay for expenses tied to the disease, according to a survey released Wednesday by the Alzheimer’s Association.
Many relatives and friends providing financial support or care to people with dementia have dipped into their retirement savings, cut back on spending and sold assets to pay for expenses tied to the disease, according to a survey released Wednesday by the Alzheimer’s Association.
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Memory training with unpredictable components could be more effective in enhancing episodic memory than training with predictable elements, according to new findings from UT Dallas researchers published in the journal Frontiers in Psychology.
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A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer’s disease later in life.
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MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Although the protein associated with Alzheimer’s disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer’s disease. The affected persons develop no clinical symptoms of the disease.
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A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer’s disease later in life.
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MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Although the protein associated with Alzheimer’s disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer’s disease. The affected persons develop no clinical symptoms of the disease.
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Dementia Big
A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer’s disease later in life.
Dementia Big
MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Although the protein associated with Alzheimer’s disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer’s disease. The affected persons develop no clinical symptoms of the disease.
Dementia Big
Despite the rates of hospital deaths in England declining, nearly two-thirds of people aged 85 and over, and more than half of people aged 95 and over still die in hospital, new research has found.
Dementia Big
Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor in neurons and a major risk factor for Alzheimer disease.
Despite the rates of hospital deaths in England declining, nearly two-thirds of people aged 85 and over, and more than half of people aged 95 and over still die in hospital, new research has found.
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Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor in neurons and a major risk factor for Alzheimer disease.
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Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor in neurons and a major risk factor for Alzheimer disease.
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Despite the rates of hospital deaths in England declining, nearly two-thirds of people aged 85 and over, and more than half of people aged 95 and over still die in hospital, new research has found.
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Every day, more than 15 million unpaid caregivers provide care to people with Alzheimer’s disease, with little outside support and often at the risk of their own health.
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Given the complex neuropathology Alzheimer’s disease (AD), combination therapy may be necessary for effective treatment. However, scientific, pragmatic, regulatory, and business challenges need to be addressed before combination therapy for AD can become a reality. Leaders from academia and industry, along with a former member of the Food and Drug Administration and the Alzheimer’s Association, have explored these challenges and here propose a strategy to facilitate proof-of-concept combination therapy trials in the near future.
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Every day, more than 15 million unpaid caregivers provide care to people with Alzheimer’s disease, with little outside support and often at the risk of their own health.
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Given the complex neuropathology Alzheimer’s disease (AD), combination therapy may be necessary for effective treatment. However, scientific, pragmatic, regulatory, and business challenges need to be addressed before combination therapy for AD can become a reality. Leaders from academia and industry, along with a former member of the Food and Drug Administration and the Alzheimer’s Association, have explored these challenges and here propose a strategy to facilitate proof-of-concept combination therapy trials in the near future.
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Dementia Big
Given the complex neuropathology Alzheimer’s disease (AD), combination therapy may be necessary for effective treatment. However, scientific, pragmatic, regulatory, and business challenges need to be addressed before combination therapy for AD can become a reality. Leaders from academia and industry, along with a former member of the Food and Drug Administration and the Alzheimer’s Association, have explored these challenges and here propose a strategy to facilitate proof-of-concept combination therapy trials in the near future.
Dementia Big
Every day, more than 15 million unpaid caregivers provide care to people with Alzheimer’s disease, with little outside support and often at the risk of their own health.
Dementia Big
The International and American Associations for Dental Research have published an article titled “Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis” in the OnlineFirst portion of the JDR Clinical & Translational Research. In it, Cerutti-Kopplin et al systematically assessed the association between oral health and cognitive function in adult populations.
Dementia Big
We investigated the change in DNA methylation in peripheral blood CD4+ lymphocytes over time, examined the relation between CD4+ lymphocytes and brain methylation, and compared their associations with AD pathology.
Dementia Big
As the discovery of the Alzheimer disease (AD) genes, APP, PSEN1, and PSEN2, in families with autosomal dominant early-onset AD (EOAD), gene discovery in familial EOAD came more or less to a standstill. Only 5% of EOAD patients are carrying a pathogenic mutation in one of the AD genes or a APOE risk allele ε4, most of EOAD patients remain unexplained. Here, we aimed at summarizing the current knowledge of EOAD genetics and its role in ongoing approaches to understand the biology of AD and disease symptomatology as well as developing new therapeutics.
Dementia Big
Here, we develop a multidomain model to predict progression of Alzheimer’s disease dementia (AD).
Here, we develop a multidomain model to predict progression of Alzheimer’s disease dementia (AD).
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Here, we develop a multidomain model to predict progression of Alzheimer’s disease dementia (AD).
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The International and American Associations for Dental Research have published an article titled “Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis” in the OnlineFirst portion of the JDR Clinical & Translational Research. In it, Cerutti-Kopplin et al systematically assessed the association between oral health and cognitive function in adult populations.
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The International and American Associations for Dental Research have published an article titled “Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis” in the OnlineFirst portion of the JDR Clinical & Translational Research. In it, Cerutti-Kopplin et al systematically assessed the association between oral health and cognitive function in adult populations.
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As the discovery of the Alzheimer disease (AD) genes, APP, PSEN1, and PSEN2, in families with autosomal dominant early-onset AD (EOAD), gene discovery in familial EOAD came more or less to a standstill. Only 5% of EOAD patients are carrying a pathogenic mutation in one of the AD genes or a APOE risk allele ε4, most of EOAD patients remain unexplained. Here, we aimed at summarizing the current knowledge of EOAD genetics and its role in ongoing approaches to understand the biology of AD and disease symptomatology as well as developing new therapeutics.
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As the discovery of the Alzheimer disease (AD) genes, APP, PSEN1, and PSEN2, in families with autosomal dominant early-onset AD (EOAD), gene discovery in familial EOAD came more or less to a standstill. Only 5% of EOAD patients are carrying a pathogenic mutation in one of the AD genes or a APOE risk allele ε4, most of EOAD patients remain unexplained. Here, we aimed at summarizing the current knowledge of EOAD genetics and its role in ongoing approaches to understand the biology of AD and disease symptomatology as well as developing new therapeutics.
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We investigated the change in DNA methylation in peripheral blood CD4+ lymphocytes over time, examined the relation between CD4+ lymphocytes and brain methylation, and compared their associations with AD pathology.
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via Stopping Dementia
We investigated the change in DNA methylation in peripheral blood CD4+ lymphocytes over time, examined the relation between CD4+ lymphocytes and brain methylation, and compared their associations with AD pathology.
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Dementia Big
Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
Dementia Big
A transition is a physical move from one location to another with a stay of at least one night. For older adults, especially those with dementia, some transitions may be unavoidable and necessary. However, unnecessary transitions are linked to problems such as medication errors, hospital readmissions, and increased risk of death.
Dementia Big
A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
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Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
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A transition is a physical move from one location to another with a stay of at least one night. For older adults, especially those with dementia, some transitions may be unavoidable and necessary. However, unnecessary transitions are linked to problems such as medication errors, hospital readmissions, and increased risk of death.
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A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
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Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
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A transition is a physical move from one location to another with a stay of at least one night. For older adults, especially those with dementia, some transitions may be unavoidable and necessary. However, unnecessary transitions are linked to problems such as medication errors, hospital readmissions, and increased risk of death.
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A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
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Researchers have found a more than twofold increase in the risk of death among patients with Parkinson’s disease who take antipsychotics, particularly typical antipsychotics.
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Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
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Tau immunotherapy has emerged as a promising approach to clear tau aggregates from the brain. Our previous findings suggest that tau antibodies may act outside and within neurons to promote such clearance.
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I’ve been a nurse for almost 32 years and one of the things that has always been difficult for me to comprehend is that all too often we treat people who are sick, having missed opportunities to prevent, screen or intervene.
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Researchers have found a more than twofold increase in the risk of death among patients with Parkinson’s disease who take antipsychotics, particularly typical antipsychotics.
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A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
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Dementia Big
Researchers have found a more than twofold increase in the risk of death among patients with Parkinson’s disease who take antipsychotics, particularly typical antipsychotics.
Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
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Dementia Big
Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.
Tau immunotherapy has emerged as a promising approach to clear tau aggregates from the brain. Our previous findings suggest that tau antibodies may act outside and within neurons to promote such clearance.
from Dementia Big http://ift.tt/1Ujw9Rw via alcoholic dementia
I’ve been a nurse for almost 32 years and one of the things that has always been difficult for me to comprehend is that all too often we treat people who are sick, having missed opportunities to prevent, screen or intervene.
from Dementia Big http://ift.tt/1Rgi2Z6 via alcoholic dementia
Dementia Big
A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer.
Dementia Big
I’ve been a nurse for almost 32 years and one of the things that has always been difficult for me to comprehend is that all too often we treat people who are sick, having missed opportunities to prevent, screen or intervene.
Dementia Big
Tau immunotherapy has emerged as a promising approach to clear tau aggregates from the brain. Our previous findings suggest that tau antibodies may act outside and within neurons to promote such clearance.
At least half of Parkinson’s disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.
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Dementia Big
At least half of Parkinson’s disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.
At least half of Parkinson’s disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.
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A new analysis based on two long-term aging studies—one of Roman Catholic nuns, the other of Japanese American men—provides what may be the most compelling evidence yet that dementia commonly results from a blend of brain ailments, rather than from a single condition. This is often the case even when an Alzheimer’s diagnosis has been given, say the researchers.
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A team of scientists at Sweden’s Linköping University has developed a molecular probe that can detect an array of different amyloid deposits in several human tissues. This new probe is extremely sensitive and was used at very low concentrations to correctly identify every positive amyloidosis sample when compared to the traditional clinical tests. The probe also picked up some amyloidosis signals that the traditional methods were unable to detect. This result means that the new probe could be used to detect amyloidosis before symptoms present, leading to faster and hence more effective treatment.
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Alzheimer’s Australia and NPS MedicineWise have today launched a new campaign to educate and empower people living with a diagnosis of dementia—and the people involved in their care—about their rights when it comes to treatment options associated with dementia.
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Dementia Big
A new analysis based on two long-term aging studies—one of Roman Catholic nuns, the other of Japanese American men—provides what may be the most compelling evidence yet that dementia commonly results from a blend of brain ailments, rather than from a single condition. This is often the case even when an Alzheimer’s diagnosis has been given, say the researchers.
Dementia Big
A team of scientists at Sweden’s Linköping University has developed a molecular probe that can detect an array of different amyloid deposits in several human tissues. This new probe is extremely sensitive and was used at very low concentrations to correctly identify every positive amyloidosis sample when compared to the traditional clinical tests. The probe also picked up some amyloidosis signals that the traditional methods were unable to detect. This result means that the new probe could be used to detect amyloidosis before symptoms present, leading to faster and hence more effective treatment.
Dementia Big
Alzheimer’s Australia and NPS MedicineWise have today launched a new campaign to educate and empower people living with a diagnosis of dementia—and the people involved in their care—about their rights when it comes to treatment options associated with dementia.
A new analysis based on two long-term aging studies—one of Roman Catholic nuns, the other of Japanese American men—provides what may be the most compelling evidence yet that dementia commonly results from a blend of brain ailments, rather than from a single condition. This is often the case even when an Alzheimer’s diagnosis has been given, say the researchers.
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via Stopping Dementia
A team of scientists at Sweden’s Linköping University has developed a molecular probe that can detect an array of different amyloid deposits in several human tissues. This new probe is extremely sensitive and was used at very low concentrations to correctly identify every positive amyloidosis sample when compared to the traditional clinical tests. The probe also picked up some amyloidosis signals that the traditional methods were unable to detect. This result means that the new probe could be used to detect amyloidosis before symptoms present, leading to faster and hence more effective treatment.
from Dementia Big http://ift.tt/1VuEpx7
via Stopping Dementia
Alzheimer’s Australia and NPS MedicineWise have today launched a new campaign to educate and empower people living with a diagnosis of dementia—and the people involved in their care—about their rights when it comes to treatment options associated with dementia.
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Dementia Big
A major challenge in the field of neurodegeneration is the unclear understanding of neuronal dysfunction. Elucidation of these patho-mechanisms could result in the identification of novel therapeutic targets. In this article, Bell et al. present an exhaustive literature review highlighting the endoplasmic reticulum (ER) kinase PERK as a crucial contributor to systemic and neurodegenerative disorders.
A major challenge in the field of neurodegeneration is the unclear understanding of neuronal dysfunction. Elucidation of these patho-mechanisms could result in the identification of novel therapeutic targets. In this article, Bell et al. present an exhaustive literature review highlighting the endoplasmic reticulum (ER) kinase PERK as a crucial contributor to systemic and neurodegenerative disorders.
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A major challenge in the field of neurodegeneration is the unclear understanding of neuronal dysfunction. Elucidation of these patho-mechanisms could result in the identification of novel therapeutic targets. In this article, Bell et al. present an exhaustive literature review highlighting the endoplasmic reticulum (ER) kinase PERK as a crucial contributor to systemic and neurodegenerative disorders.
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Dementia Big
Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.
Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.
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Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.
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In a cutting-edge treatment for Alzheimer’s disease, EPFL scientists have developed an implantable capsule that can turn the patient’s immune system against the disease.
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Researchers in the University of South Florida’s Global Center for Hearing and Speech Research, recognized as the world’s top research center for age-related hearing loss, have received a five-year, $9 million grant from the National Institutes of Health to study two unique ways to treat age-related hearing loss (ARHL).
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Women with amnestic mild cognitive impairment have better verbal memory skills than their male counterparts during the early stages of hippocampal decline.
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Siemens Healthcare has launched a range of new MR applications to help hospitals reduce the time needed for MR imaging within neurology. It is estimated that 20 to 25 per cent of all MR examinations are neurological, with the number expected to grow in 2016.
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via Stopping Dementia
Researchers in the University of South Florida’s Global Center for Hearing and Speech Research, recognized as the world’s top research center for age-related hearing loss, have received a five-year, $9 million grant from the National Institutes of Health to study two unique ways to treat age-related hearing loss (ARHL).
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Dementia Big
In a cutting-edge treatment for Alzheimer’s disease, EPFL scientists have developed an implantable capsule that can turn the patient’s immune system against the disease.
Dementia Big
Researchers in the University of South Florida’s Global Center for Hearing and Speech Research, recognized as the world’s top research center for age-related hearing loss, have received a five-year, $9 million grant from the National Institutes of Health to study two unique ways to treat age-related hearing loss (ARHL).
Siemens Healthcare has launched a range of new MR applications to help hospitals reduce the time needed for MR imaging within neurology. It is estimated that 20 to 25 per cent of all MR examinations are neurological, with the number expected to grow in 2016.
from Dementia Big http://ift.tt/1WsxL8U via alcoholic dementia
Dementia Big
Women with amnestic mild cognitive impairment have better verbal memory skills than their male counterparts during the early stages of hippocampal decline.
Dementia Big
Siemens Healthcare has launched a range of new MR applications to help hospitals reduce the time needed for MR imaging within neurology. It is estimated that 20 to 25 per cent of all MR examinations are neurological, with the number expected to grow in 2016.
In a cutting-edge treatment for Alzheimer’s disease, EPFL scientists have developed an implantable capsule that can turn the patient’s immune system against the disease.
from Dementia Big http://ift.tt/1RozkA7 via alcoholic dementia
Women with amnestic mild cognitive impairment have better verbal memory skills than their male counterparts during the early stages of hippocampal decline.
from Dementia Big http://ift.tt/1S64gZ2 via alcoholic dementia
Dementia Big
Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a study published in the open access journal Molecular Brain.
Dementia Big
Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer’s disease, according to a study published in the March 16, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.
Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a study published in the open access journal Molecular Brain.
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Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer’s disease, according to a study published in the March 16, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.
from Dementia Big http://ift.tt/1M8BiZz via alcoholic dementia
Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a study published in the open access journal Molecular Brain.
from Dementia Big http://ift.tt/1Z2HWTa
via Stopping Dementia
Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer’s disease, according to a study published in the March 16, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.
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Dementia Big
Future Science Group today announced the publication of a new article in Future Science OA, reporting data that explore the effect of frailty on the natural history of diabetes and the implications it will have for therapeutic plans in older people.
Dementia Big
The genetics underlying posterior cortical atrophy (PCA), typically a rare variant of Alzheimer’s disease (AD), remain uncertain.
Dementia Big
Changes in cognitive function and memory decline form a normal part of aging. However, in neurodegenerative diseases such as Alzheimer’s disease or mild cognitive impairment (the pre-dementia phase of Alzheimer’s disease), these changes occur more quickly. There are currently no effective treatments for these diseases.
Dementia Big
Eli Lilly said Tuesday that it’s changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer’s disease, solanezumab.
Future Science Group today announced the publication of a new article in Future Science OA, reporting data that explore the effect of frailty on the natural history of diabetes and the implications it will have for therapeutic plans in older people.
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Changes in cognitive function and memory decline form a normal part of aging. However, in neurodegenerative diseases such as Alzheimer’s disease or mild cognitive impairment (the pre-dementia phase of Alzheimer’s disease), these changes occur more quickly. There are currently no effective treatments for these diseases.
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Eli Lilly said Tuesday that it’s changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer’s disease, solanezumab.
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The genetics underlying posterior cortical atrophy (PCA), typically a rare variant of Alzheimer’s disease (AD), remain uncertain.
from Dementia Big http://ift.tt/1Rkj7SM via alcoholic dementia
Future Science Group today announced the publication of a new article in Future Science OA, reporting data that explore the effect of frailty on the natural history of diabetes and the implications it will have for therapeutic plans in older people.
from Dementia Big http://ift.tt/1WpF5SK
via Stopping Dementia
The genetics underlying posterior cortical atrophy (PCA), typically a rare variant of Alzheimer’s disease (AD), remain uncertain.
from Dementia Big http://ift.tt/1Rkj7SM
via Stopping Dementia
Changes in cognitive function and memory decline form a normal part of aging. However, in neurodegenerative diseases such as Alzheimer’s disease or mild cognitive impairment (the pre-dementia phase of Alzheimer’s disease), these changes occur more quickly. There are currently no effective treatments for these diseases.
from Dementia Big http://ift.tt/21uF9lr
via Stopping Dementia
Eli Lilly said Tuesday that it’s changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer’s disease, solanezumab.
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via Stopping Dementia
Dementia Big
Researchers from Charité - Universitätsmedizin Berlin were able to show that omega-3 fatty acid supplementation improves memory function in humans. They studied the effects of supplementation with natural omega-3 fatty acids in healthy older adults over a period of six months. Results from the study, which show that supplementation leads to significant improvements in memory function, have been published in the current issue of the Journal of Alzheimer’s Disease.
Dementia Big
The corticobasal syndrome (CBS) constitutes a neurodegenerative disease spectrum with substantial phenotypical or biological heterogeneity, requiring large or multimodal studies to identify its clinico-biological signature while disentangling Alzheimer’s disease (AD)-related from non-AD-related CBS.
Dementia Big
Today, Alzheimer’s disease is diagnosed too late. In collaboration with a research team at the university and German Center for Neurogenerative Diseases in Göttingen, Researchers at Ruhr-Universität Bochum have developed a blood test that may potentially facilitate detection of Alzheimer’s at an early stage. It is based on an immuno-chemical analysis using an infrared sensor.
Dementia Big
Alzheimer’s disease (AD) is among the most significant health care burdens. Disappointing results from clinical trials in late-stage AD persons combined with hopeful results from trials in persons with early-stage suggest that research in the preclinical stage of AD is necessary to define an optimal therapeutic success window. We review the justification for conducting trials in the preclinical stage and highlight novel ethical challenges that arise and are related to determining appropriate risk-benefit ratios and disclosing individuals’ biomarker status.
Researchers from Charité – Universitätsmedizin Berlin were able to show that omega-3 fatty acid supplementation improves memory function in humans. They studied the effects of supplementation with natural omega-3 fatty acids in healthy older adults over a period of six months. Results from the study, which show that supplementation leads to significant improvements in memory function, have been published in the current issue of the Journal of Alzheimer’s Disease.
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The corticobasal syndrome (CBS) constitutes a neurodegenerative disease spectrum with substantial phenotypical or biological heterogeneity, requiring large or multimodal studies to identify its clinico-biological signature while disentangling Alzheimer’s disease (AD)-related from non-AD-related CBS.
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Today, Alzheimer’s disease is diagnosed too late. In collaboration with a research team at the university and German Center for Neurogenerative Diseases in Göttingen, Researchers at Ruhr-Universität Bochum have developed a blood test that may potentially facilitate detection of Alzheimer’s at an early stage. It is based on an immuno-chemical analysis using an infrared sensor.
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Alzheimer’s disease (AD) is among the most significant health care burdens. Disappointing results from clinical trials in late-stage AD persons combined with hopeful results from trials in persons with early-stage suggest that research in the preclinical stage of AD is necessary to define an optimal therapeutic success window. We review the justification for conducting trials in the preclinical stage and highlight novel ethical challenges that arise and are related to determining appropriate risk-benefit ratios and disclosing individuals’ biomarker status.
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Researchers from Charité - Universitätsmedizin Berlin were able to show that omega-3 fatty acid supplementation improves memory function in humans. They studied the effects of supplementation with natural omega-3 fatty acids in healthy older adults over a period of six months. Results from the study, which show that supplementation leads to significant improvements in memory function, have been published in the current issue of the Journal of Alzheimer’s Disease.
from Dementia Big http://ift.tt/1QV4qDO via alcoholic dementia
Alzheimer’s disease (AD) is among the most significant health care burdens. Disappointing results from clinical trials in late-stage AD persons combined with hopeful results from trials in persons with early-stage suggest that research in the preclinical stage of AD is necessary to define an optimal therapeutic success window. We review the justification for conducting trials in the preclinical stage and highlight novel ethical challenges that arise and are related to determining appropriate risk-benefit ratios and disclosing individuals’ biomarker status.
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Today, Alzheimer’s disease is diagnosed too late. In collaboration with a research team at the university and German Center for Neurogenerative Diseases in Göttingen, Researchers at Ruhr-Universität Bochum have developed a blood test that may potentially facilitate detection of Alzheimer’s at an early stage. It is based on an immuno-chemical analysis using an infrared sensor.
from Dementia Big http://ift.tt/1Wn1lfZ via alcoholic dementia
The corticobasal syndrome (CBS) constitutes a neurodegenerative disease spectrum with substantial phenotypical or biological heterogeneity, requiring large or multimodal studies to identify its clinico-biological signature while disentangling Alzheimer’s disease (AD)-related from non-AD-related CBS.
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To meet the challenge of Alzheimer’s disease and other dementias, a concerted effort and long-term economic commitment is needed, according to a new expert report by internationally leading researchers in the field. The journal Lancet Neurology devotes its entire April issue to a detailed overview and recommendations about how patient care, as well as basic and clinical research on Alzheimer’s disease and other dementias should be organised in the future. The report will be presented at a workshop hosted by the European Parliament in Brussels on March 15, during the Brain Awareness Week 2016
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The blueberry, already labeled a “super fruit” for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams.
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A researcher from the University of Granada (UGR) has designed an accessible tale aimed at people with intellectual disability, which allows them to “read a story even if they cannot read”, since it has been ‘written’ using an illustration-based graphic language as the only narrative thread.
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Dementia Big
A researcher from the University of Granada (UGR) has designed an accessible tale aimed at people with intellectual disability, which allows them to “read a story even if they cannot read”, since it has been ‘written’ using an illustration-based graphic language as the only narrative thread.
Dementia Big
To meet the challenge of Alzheimer’s disease and other dementias, a concerted effort and long-term economic commitment is needed, according to a new expert report by internationally leading researchers in the field. The journal Lancet Neurology devotes its entire April issue to a detailed overview and recommendations about how patient care, as well as basic and clinical research on Alzheimer’s disease and other dementias should be organised in the future. The report will be presented at a workshop hosted by the European Parliament in Brussels on March 15, during the Brain Awareness Week 2016
Dementia Big
The blueberry, already labeled a “super fruit” for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams.
A researcher from the University of Granada (UGR) has designed an accessible tale aimed at people with intellectual disability, which allows them to “read a story even if they cannot read”, since it has been ‘written’ using an illustration-based graphic language as the only narrative thread.
from Dementia Big http://ift.tt/24Zz196 via alcoholic dementia
To meet the challenge of Alzheimer’s disease and other dementias, a concerted effort and long-term economic commitment is needed, according to a new expert report by internationally leading researchers in the field. The journal Lancet Neurology devotes its entire April issue to a detailed overview and recommendations about how patient care, as well as basic and clinical research on Alzheimer’s disease and other dementias should be organised in the future. The report will be presented at a workshop hosted by the European Parliament in Brussels on March 15, during the Brain Awareness Week 2016
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The blueberry, already labeled a “super fruit” for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams.
from Dementia Big http://ift.tt/22d7tOV via alcoholic dementia
The blueberry, already labeled a ‘super fruit’ for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams. The fruit is loaded with healthful antioxidants, and these substances could help prevent the devastating effects of this increasingly common form of dementia, scientists report.
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The blueberry, already labeled a ‘super fruit’ for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams. The fruit is loaded with healthful antioxidants, and these substances could help prevent the devastating effects of this increasingly common form of dementia, scientists report.
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Dementia Big
The blueberry, already labeled a ‘super fruit’ for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. New research being presented today further bolsters this idea, which is being tested by many teams. The fruit is loaded with healthful antioxidants, and these substances could help prevent the devastating effects of this increasingly common form of dementia, scientists report.
Recently, researchers compared the effects of tai chi to leg strengthening exercises (a physical therapy called “lower extremity training,” or LET) in reducing falls. Falls are a leading cause of serious injuries in older adults and can lead to hospitalization, nursing home admission, and even death.
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Recently, researchers compared the effects of tai chi to leg strengthening exercises (a physical therapy called “lower extremity training,” or LET) in reducing falls. Falls are a leading cause of serious injuries in older adults and can lead to hospitalization, nursing home admission, and even death.
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Dementia Big
Recently, researchers compared the effects of tai chi to leg strengthening exercises (a physical therapy called “lower extremity training,” or LET) in reducing falls. Falls are a leading cause of serious injuries in older adults and can lead to hospitalization, nursing home admission, and even death.
Dementia Big
Topline results from the European LipiDiDiet clinical trial were presented today as part of a late-breaking presentation at the Advances in Alzheimer’s Therapy congress.
Dementia Big
More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.
Topline results from the European LipiDiDiet clinical trial were presented today as part of a late-breaking presentation at the Advances in Alzheimer’s Therapy congress.
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More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.
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Topline results from the European LipiDiDiet clinical trial were presented today as part of a late-breaking presentation at the Advances in Alzheimer’s Therapy congress.
from Dementia Big http://ift.tt/1RbUscZ
via Stopping Dementia
More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.
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via Stopping Dementia
A new study, jointly led by the University of Southampton and King’s College London, has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
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Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
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Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
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A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King’s College London, determined the mechanism of Alzheimer’s disease development and possibly distinguished its key trigger. Their article was published in Scientific Reports.
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A new study shows that a variety of physical activities from walking to gardening and dancing can improve brain volume and cut the risk of Alzheimer’s disease by 50%.
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A new study jointly led by King’s College London and the University of Southampton has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
from Dementia Big http://ift.tt/1LeSKLK via alcoholic dementia
A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King’s College London, determined the mechanism of Alzheimer’s disease development and possibly distinguished its key trigger. Their article was published in Scientific Reports.
from Dementia Big http://ift.tt/1pcxn3p
via Stopping Dementia
A new study, jointly led by the University of Southampton and King’s College London, has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
from Dementia Big http://ift.tt/1pcAmJ4
via Stopping Dementia
Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
from Dementia Big http://ift.tt/1XhuclP
via Stopping Dementia
A new study shows that a variety of physical activities from walking to gardening and dancing can improve brain volume and cut the risk of Alzheimer’s disease by 50%.
from Dementia Big http://ift.tt/21m4PjY
via Stopping Dementia
Dementia Big
A new study, jointly led by the University of Southampton and King’s College London, has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
from Dementia Big http://ift.tt/1YEOuXR
via Stopping Dementia
A new study jointly led by King’s College London and the University of Southampton has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
from Dementia Big http://ift.tt/1LeSKLK
via Stopping Dementia
Dementia Big
A new study shows that a variety of physical activities from walking to gardening and dancing can improve brain volume and cut the risk of Alzheimer’s disease by 50%.
Dementia Big
A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King’s College London, determined the mechanism of Alzheimer’s disease development and possibly distinguished its key trigger. Their article was published in Scientific Reports.
Dementia Big
Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
Dementia Big
Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.
Dementia Big
A new study jointly led by King’s College London and the University of Southampton has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.
The study did not find a significant benefit in broad cognitive function (the study primary endpoint). Cognitive decline over the study period was less than originally expected when it was designed ten years ago, so differences found between the two groups were too small to be statistically significant. Project coordinator Professor Tobias Hartmann, Saarland University Germany, explained that this is the most likely reason the primary endpoint was not met.
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A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).
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A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).
from Dementia Big http://ift.tt/1UgHlMT via alcoholic dementia
The study did not find a significant benefit in broad cognitive function (the study primary endpoint). Cognitive decline over the study period was less than originally expected when it was designed ten years ago, so differences found between the two groups were too small to be statistically significant. Project coordinator Professor Tobias Hartmann, Saarland University Germany, explained that this is the most likely reason the primary endpoint was not met.
from Dementia Big http://ift.tt/1XfalnB via alcoholic dementia
Dementia Big
A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).
Dementia Big
The study did not find a significant benefit in broad cognitive function (the study primary endpoint). Cognitive decline over the study period was less than originally expected when it was designed ten years ago, so differences found between the two groups were too small to be statistically significant. Project coordinator Professor Tobias Hartmann, Saarland University Germany, explained that this is the most likely reason the primary endpoint was not met.
A portable biosensor that could show how disease is progressing in patients with Alzheimer’s could greatly improve people’s quality of life in the future, according to a new review published in Biosensors and Bioelectronics.
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The combined impact of dementia, age-related hearing and vision impairment is to be investigated by a new multi-million European research consortium led by The University of Manchester.
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via Stopping Dementia
A worldwide team of senior scientists and clinicians have come together to produce an editorial which indicates that certain microbes – a specific virus and two specific types of bacteria—are major causes of Alzheimer’s disease. Their paper, which has been published online in the highly regarded peer-reviewed journal, Journal of Alzheimer’s disease, stresses the urgent need for further research—and more importantly, for clinical trials of anti-microbial and related agents to treat the disease.
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via Stopping Dementia
The combined impact of dementia, age-related hearing and vision impairment is to be investigated by a new multi-million European research consortium led by The University of Manchester.
from Dementia Big http://ift.tt/1RRlwBi via alcoholic dementia
A worldwide team of senior scientists and clinicians have come together to produce an editorial which indicates that certain microbes - a specific virus and two specific types of bacteria—are major causes of Alzheimer’s disease. Their paper, which has been published online in the highly regarded peer-reviewed journal, Journal of Alzheimer’s disease, stresses the urgent need for further research—and more importantly, for clinical trials of anti-microbial and related agents to treat the disease.
from Dementia Big http://ift.tt/1R6baKH via alcoholic dementia
A portable biosensor that could show how disease is progressing in patients with Alzheimer’s could greatly improve people’s quality of life in the future, according to a new review published in Biosensors and Bioelectronics.
from Dementia Big http://ift.tt/1R7sHsc via alcoholic dementia
Dementia Big
The combined impact of dementia, age-related hearing and vision impairment is to be investigated by a new multi-million European research consortium led by The University of Manchester.
Dementia Big
A portable biosensor that could show how disease is progressing in patients with Alzheimer’s could greatly improve people’s quality of life in the future, according to a new review published in Biosensors and Bioelectronics.
Dementia Big
A worldwide team of senior scientists and clinicians have come together to produce an editorial which indicates that certain microbes - a specific virus and two specific types of bacteria—are major causes of Alzheimer’s disease. Their paper, which has been published online in the highly regarded peer-reviewed journal, Journal of Alzheimer’s disease, stresses the urgent need for further research—and more importantly, for clinical trials of anti-microbial and related agents to treat the disease.
Dementia Big
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer’s disease, and Parkinson’s disease.
Dementia Big
A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells.
Dementia Big
A leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults think it is possible to reduce their risk of developing the condition.
Dementia Big
A leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults think it is possible to reduce their risk of developing the condition.
Dementia Big
The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease – which results in language loss – when it is caused by a buildup of a toxic protein found in Alzheimer’s disease.
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer’s disease, and Parkinson’s disease.
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A leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults think it is possible to reduce their risk of developing the condition.
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