Wednesday, December 16, 2015

Unraveling the mechanistic complexity of Alzheimer's disease through systems biology

Unraveling the mechanistic complexity of Alzheimer's disease through systems biology:

Dementia Big
Alzheimer’s disease (AD) is a complex, multifactorial disease that has reached global epidemic proportions. The challenge remains to fully identify its underlying molecular mechanisms that will enable development of accurate diagnostic tools and therapeutics. Conventional experimental approaches that target individual or small sets of genes or proteins may overlook important parts of the regulatory network, which limits the opportunity of identifying multitarget interventions. Our perspective is that a more complete insight into potential treatment options for AD will only be made possible through studying the disease as a system.


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