Alzheimer's researchers find clues to toxic forms of amyloid beta

Alzheimer's researchers find clues to toxic forms of amyloid beta:

Dementia Big
Much of the research on Alzheimer’s disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. In recent years, attention has turned away from the fibrils themselves to an intermediate stage in the aggregation of amyloid beta. “Oligomers” consisting of a few molecules of the protein stuck together are more mobile than the large, insoluble fibrils and seem to be much more toxic. But the actual structure of these soluble oligomers remains unknown, and it’s unclear how they trigger the neurotoxic effects that lead to Alzheimer’s disease.

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