Alzheimer's gene associated with failure to adapt to cognitive challenge in healthy adults

Alzheimer's gene associated with failure to adapt to cognitive challenge in healthy adults:

Dementia Big
Healthy adults carrying the gene APOE4—the strongest known genetic risk factor for Alzheimer’s disease (AD)—may struggle to adapt their brain activity to increasing cognitive demands as they get older, according to a study published in The Journal of Neuroscience. This age-related effect, which was not observed in people without the risk factor, suggests that interventions targeting cognitive decline in at-risk populations may need to begin many years before any symptoms of the disease emerge in order to be effective.

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