In a comprehensive analysis of samples from 107 aged human brains, researchers at the Allen Institute for Brain Science, UW Medicine and Kaiser Permanente Washington Health Research Institute have discovered details that will help researchers better understand the biological bases for Alzheimer’s disease and dementia in older populations. The analysis also highlights surprising variability in the aged brain, including examples of donors with resilience to pathology. The research is published this month in the journal eLife, and the data underlying the research are publicly available as part of the suite of open data resources at the Allen Brain Atlas portal.
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