Friday, January 5, 2018

Team develops world-first array of compounds for detection, imaging of Alzheimer's disease

Hong Kong Baptist University (HKBU) chemists have invented a new class of multifunctional cyanine compounds that can be used for detection, imaging and treatment of Alzheimer’s disease. The research team was jointly led by Professor Ricky Wong Man-shing and Associate Professor Dr Li Hung-wing, with members from the Department of Chemistry of HKBU. By making use of the proprietary compounds, the HKBU team has proved that cyanine compounds applied on a nano-detection platform can quantify trace amounts of Alzheimer’s disease-related protein biomarkers present in human fluids such as cerebrospinal fluid, serum, saliva, and urine. It is a rapid, low-cost and ultrasensitive detection assay. The compounds also serve as an imaging agent for in vivo detection and monitoring of disease progression and understanding the disease pathogenesis, as well as a drug candidate for treatment of the disease.

from Dementia Big http://ift.tt/2CIOAgd via alcoholic dementia


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