Late-onset sporadic Alzheimer’s disease (AD) accounts for about 99 percent of all cases, and is linked to multiple factors and pathogenetic mechanisms. One important contributor is a protein post-translational modification (PTM), known as O-linked β-N-acetylglucosamine, or O-GlcNAc.
from Dementia Big http://ift.tt/2gv3CJx via alcoholic dementia
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