Clarity Pointe announces groundbreaking of new memory care community in Tallahassee

Clarity Pointe is excited to announce the groundbreaking of its newest memory care community, Clarity Pointe Tallahassee.

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Clarity Pointe announces groundbreaking of new memory care community in Tallahassee

Clarity Pointe announces groundbreaking of new memory care community in Tallahassee:

Dementia Big
Clarity Pointe is excited to announce the groundbreaking of its newest memory care community, Clarity Pointe Tallahassee.

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Pot may restrict blood flow to brain: study

Pot may restrict blood flow to brain: study:

Dementia Big
(HealthDay)—Marijuana appears to hamper blood flow to the brain, which theoretically could affect your memory and ability to reason, a new study suggests.

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Pot may restrict blood flow to brain: study

(HealthDay)—Marijuana appears to hamper blood flow to the brain, which theoretically could affect your memory and ability to reason, a new study suggests.

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Two research studies on new molecules could potentially treat Alzheimer's disease

Two research studies on new molecules could potentially treat Alzheimer's disease:

Dementia Big
This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer’s disease.

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Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer’s disease.

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Investigation into new molecules for potential Alzheimer's treatment

Investigation into new molecules for potential Alzheimer's treatment:

Dementia Big
Two significant research studies have been published in Molecular Pharmaceutics and Current Alzheimer Research regarding molecules that could potentially treat Alzheimer’s disease. The chief researcher in both studies was Yan Ivanenkov, the head of the Laboratory of Medical Chemistry and Bioinformatics at MIPT. Mark Veselov, another MIPT employee, also participated in the second study.

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Can paint strokes help identify Alzheimer's?

Can paint strokes help identify Alzheimer's?:

Dementia Big
A new University of Liverpool study published today in Neuropsychology shows that it may be possible to detect neurodegenerative disorders in artists before they are diagnosed.

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Investigation into new molecules for potential Alzheimer's treatment

Two significant research studies have been published in Molecular Pharmaceutics and Current Alzheimer Research regarding molecules that could potentially treat Alzheimer’s disease. The chief researcher in both studies was Yan Ivanenkov, the head of the Laboratory of Medical Chemistry and Bioinformatics at MIPT. Mark Veselov, another MIPT employee, also participated in the second study.

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Can paint strokes help identify Alzheimer's?

A new University of Liverpool study published today in Neuropsychology shows that it may be possible to detect neurodegenerative disorders in artists before they are diagnosed.

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'Friendship Bench' approach holds potential to improve lives of people with mental health problems

'Friendship Bench' approach holds potential to improve lives of people with mental health problems:

Dementia Big
Their offices are simple wooden seats, called Friendship Benches, located in the grounds of health clinics around Harare and other major cities in Zimbabwe.

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'Friendship Bench' approach holds potential to improve lives of people with mental health problems

Their offices are simple wooden seats, called Friendship Benches, located in the grounds of health clinics around Harare and other major cities in Zimbabwe.

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Is dementia in older women tied to 20-year rate of weight loss?

(HealthDay)—For women surviving into late life, the rate of weight loss over 20 years is associated with development of mild cognitive impairment (MCI) or dementia, according to a study published online Dec. 19 in the Journal of the American Geriatrics Society.

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Investigational new drug for Alzheimer's scheduled for first study in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration (FDA) that testing in humans may proceed for an investigational new drug for Alzheimer’s disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

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Is dementia in older women tied to 20-year rate of weight loss?

Is dementia in older women tied to 20-year rate of weight loss?:

Dementia Big
(HealthDay)—For women surviving into late life, the rate of weight loss over 20 years is associated with development of mild cognitive impairment (MCI) or dementia, according to a study published online Dec. 19 in the Journal of the American Geriatrics Society.

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Investigational new drug for Alzheimer's scheduled for first study in humans

Investigational new drug for Alzheimer's scheduled for first study in humans:

Dementia Big
Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration (FDA) that testing in humans may proceed for an investigational new drug for Alzheimer’s disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

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The dawn of mRNA-based therapeutics for brain diseases

The dawn of mRNA-based therapeutics for brain diseases:

Dementia Big
The progressive dementia suffered by patients with Alzheimer’s disease (AD) affects millions of people globally each year and puts considerable strain on healthcare services. The mechanisms behind AD are not yet clear, and there are no effective therapies available to fully tackle the disease.

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Sleep changes without medial temporal lobe or brain cortical changes in community-dwelling individuals with subjective cognitive decline

Sleep changes without medial temporal lobe or brain cortical changes in community-dwelling individuals with subjective cognitive decline:

Dementia Big
Subjective cognitive decline (SCD) is a risk factor for mild cognitive impairment (MCI) and Alzheimer disease (AD). Although sleep has been shown to be altered in MCI and AD, little is known about sleep in SCD.

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The dawn of mRNA-based therapeutics for brain diseases

The progressive dementia suffered by patients with Alzheimer’s disease (AD) affects millions of people globally each year and puts considerable strain on healthcare services. The mechanisms behind AD are not yet clear, and there are no effective therapies available to fully tackle the disease.

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Sleep changes without medial temporal lobe or brain cortical changes in community-dwelling individuals with subjective cognitive decline

Subjective cognitive decline (SCD) is a risk factor for mild cognitive impairment (MCI) and Alzheimer disease (AD). Although sleep has been shown to be altered in MCI and AD, little is known about sleep in SCD.

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Synergistic interaction between amyloid and tau predicts the progression to dementia

Synergistic interaction between amyloid and tau predicts the progression to dementia:

Dementia Big
Recent literature proposes that amyloid-β and phosphorylated tau (p-tau) synergism accelerates biomarker abnormalities in controls. Yet, it remains to be answered whether this synergism is the driving force behind Alzheimer disease (AD) dementia.

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Synergistic interaction between amyloid and tau predicts the progression to dementia

Recent literature proposes that amyloid-β and phosphorylated tau (p-tau) synergism accelerates biomarker abnormalities in controls. Yet, it remains to be answered whether this synergism is the driving force behind Alzheimer disease (AD) dementia.

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Supercharged sprout vitamin inspiration for new Alzheimer's drug research

Supercharged sprout vitamin inspiration for new Alzheimer's drug research:

Dementia Big
A supercharged version of the acid derived from our Christmas dinner veg is the basis of new research aimed at developing a new drug to treat Alzheimer’s disease.

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Supercharged sprout vitamin inspiration for new Alzheimer's drug research

A supercharged version of the acid derived from our Christmas dinner veg is the basis of new research aimed at developing a new drug to treat Alzheimer’s disease.

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Occupational therapy holds potential to provide clinical benefits to dementia patients

Occupational therapy holds potential to provide clinical benefits to dementia patients:

Dementia Big
A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a research study published in the Journal of Alzheimer’s Disease this month.

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Risk of incident clinical diagnosis of Alzheimer's disease–type dementia attributable to pathology-confirmed vascular disease

Risk of incident clinical diagnosis of Alzheimer's disease–type dementia attributable to pathology-confirmed vascular disease:

Dementia Big
The presence of cerebrovascular pathology may increase the risk of clinical diagnosis of Alzheimer’s disease (AD).

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Promising discovery for a non-invasive early detection of Alzheimer's disease

Promising discovery for a non-invasive early detection of Alzheimer's disease:

Dementia Big
A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the prestigious “Journal of Alzheimer’s Disease (JAD)”, entitled “Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer’s Disease”. This paper has been highlighted as one of the most important contribution to this field. The paper stems from a fruitful collaboration between the neuroscience laboratory from the International Center for Biomedicine (ICC) under the leadership of Dr. Ricardo Maccioni and the research teams of Drs. Andrea Slachevsky, Faculty of Medicine, University of Chile, together with Drs. Oscar Lopez and James Becker from University of Pittsburgh, School of Medicine, USA.

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Occupational therapy holds potential to provide clinical benefits to dementia patients

A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a research study published in the Journal of Alzheimer’s Disease this month.

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Promising discovery for a non-invasive early detection of Alzheimer's disease

A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the prestigious “Journal of Alzheimer’s Disease (JAD)”, entitled “Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer’s Disease”. This paper has been highlighted as one of the most important contribution to this field. The paper stems from a fruitful collaboration between the neuroscience laboratory from the International Center for Biomedicine (ICC) under the leadership of Dr. Ricardo Maccioni and the research teams of Drs. Andrea Slachevsky, Faculty of Medicine, University of Chile, together with Drs. Oscar Lopez and James Becker from University of Pittsburgh, School of Medicine, USA.

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Risk of incident clinical diagnosis of Alzheimer's disease–type dementia attributable to pathology-confirmed vascular disease

The presence of cerebrovascular pathology may increase the risk of clinical diagnosis of Alzheimer’s disease (AD).

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Occupational therapy may have the potential to slow down functional decline and reduce behavioral troubles

Occupational therapy may have the potential to slow down functional decline and reduce behavioral troubles:

Dementia Big
A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a research study published in the Journal of Alzheimer’s Disease this month. The research suggested the influence of occupational therapy on reducing behavioral troubles, caregivers’ burden and amount of informal care over the intervention period and a stabilization over the 3-months period thereafter.

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New detection method could lead to noninvasive diagnosis of Creutzfeldt-Jakob disease

New detection method could lead to noninvasive diagnosis of Creutzfeldt-Jakob disease:

Dementia Big
The detection of prions in the blood of patients with variant Creutzfeldt-Jakob disease could lead to a noninvasive diagnosis prior to symptoms and a way to identify prion contamination of the donated blood supply, according to researchers at McGovern Medical School at The University of Texas Health Science Center at Houston.

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Occupational therapy may have the potential to slow down functional decline and reduce behavioral troubles

A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a research study published in the Journal of Alzheimer’s Disease this month. The research suggested the influence of occupational therapy on reducing behavioral troubles, caregivers’ burden and amount of informal care over the intervention period and a stabilization over the 3-months period thereafter.

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New detection method could lead to noninvasive diagnosis of Creutzfeldt-Jakob disease

The detection of prions in the blood of patients with variant Creutzfeldt-Jakob disease could lead to a noninvasive diagnosis prior to symptoms and a way to identify prion contamination of the donated blood supply, according to researchers at McGovern Medical School at The University of Texas Health Science Center at Houston.

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Rejuvenating the brain's disposal system

A characteristic feature of Alzheimer’s disease is the presence of so called amyloid plaques in the patient’s brain - aggregates of misfolded proteins that clump together and damage nerve cells. Although the body has mechanisms to dispose these aggregates, it apparently cannot keep up with the load in the diseased brain. Researchers from the German Center for Neurodegenerative Diseases (DZNE), Munich and the Ludwig Maximilians University (LMU) Munich have now discovered a strategy to help the brain remove amyloid plaques. More precisely: they uncovered a factor that can activate microglial cells to engulf newly forming clumps in the brain. Microglia are the scavenger cells of the brain’s immune system that function in keeping the brain tidy and free of any damaging material. The work is published today in The EMBO Journal.

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UCLA study shows how the brain initiates repair by generating replacement cells after stroke

UCLA researchers have shown that the brain can be repaired — and brain function can be recovered — after a stroke in animals.

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Scientists identify potential drug treatment in fight against Alzheimer’s disease

An international team of scientists has announced a new advance in the fight against Alzheimer’s disease by identifying a new drug target for not only improving symptoms of brain degeneration – but also to extend the life-span of the terminally ill mice.

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Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease.

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Rejuvenating the brain's disposal system

Rejuvenating the brain's disposal system:

Dementia Big
A characteristic feature of Alzheimer’s disease is the presence of so called amyloid plaques in the patient’s brain - aggregates of misfolded proteins that clump together and damage nerve cells. Although the body has mechanisms to dispose these aggregates, it apparently cannot keep up with the load in the diseased brain. Researchers from the German Center for Neurodegenerative Diseases (DZNE), Munich and the Ludwig Maximilians University (LMU) Munich have now discovered a strategy to help the brain remove amyloid plaques. More precisely: they uncovered a factor that can activate microglial cells to engulf newly forming clumps in the brain. Microglia are the scavenger cells of the brain’s immune system that function in keeping the brain tidy and free of any damaging material. The work is published today in The EMBO Journal.

http://ift.tt/2hbaZq3

UCLA study shows how the brain initiates repair by generating replacement cells after stroke

UCLA study shows how the brain initiates repair by generating replacement cells after stroke:

Dementia Big
UCLA researchers have shown that the brain can be repaired — and brain function can be recovered — after a stroke in animals.

http://ift.tt/2igztff

Scientists identify potential drug treatment in fight against Alzheimer’s disease

Scientists identify potential drug treatment in fight against Alzheimer’s disease:

Dementia Big
An international team of scientists has announced a new advance in the fight against Alzheimer’s disease by identifying a new drug target for not only improving symptoms of brain degeneration – but also to extend the life-span of the terminally ill mice.

http://ift.tt/2haVL4w

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists detail structure of molecule implicated in Alzheimer's disease:

Dementia Big
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease.

http://ift.tt/2igAJ1U

Simple sniff test can enhance accuracy of diagnosing Alzheimer's disease

Tests that measure the sense of smell may soon become common in neurologists’ offices.

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Biomarker validation: Methods and matrix matter

We read with interest the research article from Casanova et al. for an upcoming edition of Alzheimer’s & Dementia (2016, article in press). We appreciate the efforts that these investigators have expended in attempting to replicate our plasma lipidomic findings in preclinical Alzheimer’s disease [1]. We enthusiastically endorse independent validation of new findings in science but assert that valid replication requires identical methods including those related to clinical characterization and biospecimen collection, processing, and analysis.

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Simple sniff test can enhance accuracy of diagnosing Alzheimer's disease

Simple sniff test can enhance accuracy of diagnosing Alzheimer's disease:

Dementia Big
Tests that measure the sense of smell may soon become common in neurologists’ offices.

http://ift.tt/2hGOiuA

Biomarker validation: Methods and matrix matter

Biomarker validation: Methods and matrix matter:

Dementia Big
We read with interest the research article from Casanova et al. for an upcoming edition of Alzheimer’s & Dementia (2016, article in press). We appreciate the efforts that these investigators have expended in attempting to replicate our plasma lipidomic findings in preclinical Alzheimer’s disease [1]. We enthusiastically endorse independent validation of new findings in science but assert that valid replication requires identical methods including those related to clinical characterization and biospecimen collection, processing, and analysis.

http://ift.tt/2hSHE2B

Study details molecular roots of Alzheimer's

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule—and how that shape may be disrupted by certain genetic mutations—can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

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Study confirms 'sniff test' may be useful in diagnosing early Alzheimer's disease

Tests that measure the sense of smell may soon become common in neurologists’ offices. Scientists have been finding increasing evidence that the sense of smell declines sharply in the early stages of Alzheimer’s, and now a new study from the Perelman School of Medicine at the University of Pennsylvania published today in the Journal of Alzheimer’s Disease confirms that administering a simple “sniff test” can enhance the accuracy of diagnosing this dreaded disease.

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Study details molecular roots of Alzheimer's

Study details molecular roots of Alzheimer's:

Dementia Big
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule—and how that shape may be disrupted by certain genetic mutations—can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

http://ift.tt/2ha9TwF

Study confirms 'sniff test' may be useful in diagnosing early Alzheimer's disease

Study confirms 'sniff test' may be useful in diagnosing early Alzheimer's disease:

Dementia Big
Tests that measure the sense of smell may soon become common in neurologists’ offices. Scientists have been finding increasing evidence that the sense of smell declines sharply in the early stages of Alzheimer’s, and now a new study from the Perelman School of Medicine at the University of Pennsylvania published today in the Journal of Alzheimer’s Disease confirms that administering a simple “sniff test” can enhance the accuracy of diagnosing this dreaded disease.

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Holiday tips and gift suggestions for caregivers, families of AD patients

The holidays are supposed to be a time of joy and celebration, but we all know they can be stressful even under the best of circumstances.

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Landmark clinical trial to test third investigational drug for Alzheimer's disease

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer’s disease.

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Holiday tips and gift suggestions for caregivers, families of AD patients

Holiday tips and gift suggestions for caregivers, families of AD patients:

Dementia Big
The holidays are supposed to be a time of joy and celebration, but we all know they can be stressful even under the best of circumstances.

http://ift.tt/2hneXtm

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Landmark clinical trial to test third investigational drug for Alzheimer's disease:

Dementia Big
An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer’s disease.

http://ift.tt/2h89Hhk

Alzheimer's advance: Early stage study in mice show new drugs restore memory loss and prolong life

“We have treated mice with a new type of drug, and found that these drugs can not only improve symptoms of brain degeneration, such as cognitive decline, but can also extend the life-span of these terminally-sick mice. Our study opens up avenues for researchers to look at new drugs that treat the symptoms of Alzheimer’s and also slow disease progression”- Professor Andrew Tobin

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Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

Memory loss and other cognitive symptoms of Alzheimer’s disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are a common treatment for patients with Alzheimer’s; however, in spite of their clinical benefits, these non-selective medications are also associated with numerous adverse effects. It has been hypothesized that more selective targeting of acetylcholine signaling may reduce the side effects associated with current Alzheimer’s medications, but it’s not known whether improving selectivity could decrease the treatment’s efficacy.

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Landmark Alzheimer's prevention trial to evaluate third drug

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer’s disease.

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New biomarker predicts Alzheimer's disease and link to diabetes

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline.

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http://ift.tt/2h5ZvFS

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease:

Dementia Big
Memory loss and other cognitive symptoms of Alzheimer’s disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are a common treatment for patients with Alzheimer’s; however, in spite of their clinical benefits, these non-selective medications are also associated with numerous adverse effects. It has been hypothesized that more selective targeting of acetylcholine signaling may reduce the side effects associated with current Alzheimer’s medications, but it’s not known whether improving selectivity could decrease the treatment’s efficacy.

http://ift.tt/2hl12nH

Alzheimer's advance: Early stage study in mice show new drugs restore memory loss and prolong life

Alzheimer's advance: Early stage study in mice show new drugs restore memory loss and prolong life:

Dementia Big
“We have treated mice with a new type of drug, and found that these drugs can not only improve symptoms of brain degeneration, such as cognitive decline, but can also extend the life-span of these terminally-sick mice. Our study opens up avenues for researchers to look at new drugs that treat the symptoms of Alzheimer’s and also slow disease progression”- Professor Andrew Tobin

http://ift.tt/2h5WtBH

Landmark Alzheimer's prevention trial to evaluate third drug

Landmark Alzheimer's prevention trial to evaluate third drug:

Dementia Big
An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer’s disease.

http://ift.tt/2hkTOQG

New biomarker predicts Alzheimer's disease and link to diabetes

New biomarker predicts Alzheimer's disease and link to diabetes:

Dementia Big
An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline.

http://ift.tt/2h5St48

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies

Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer’s disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer’s Association and the Alzheimer’s Drug Discovery Foundation convened a one-day workshop to delve into this discussion.

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Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies:

Dementia Big
Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer’s disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer’s Association and the Alzheimer’s Drug Discovery Foundation convened a one-day workshop to delve into this discussion.

http://ift.tt/2hw7V8S

Rutgers expert shares tips for Alzheimer’s and dementia caregiving during the holidays

The holidays can be an especially challenging time for family caregivers of people with dementia or Alzheimer’s disease.

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Frequent sauna bathing protects men against dementia

Frequent sauna bathing can reduce the risk of dementia, according to a recent study carried out at the University of Eastern Finland. In a 20-year follow-up, men taking a sauna four to seven times a week were 66 percent less likely to be diagnosed with dementia than those taking a sauna once a week. The association between sauna bathing and dementia risk has not been previously investigated.

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Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Researchers at the University of Surrey, in collaboration with the Universities of Reading and Cologne, and the Royal Berkshire Hospital, have discovered that it is possible to stop the activation of a group of proteins (NADPH Oxidase) known to cause most of the diseases of ageing.

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New approach to analyzing brain patterns appears to help reduce people’s fear, build confidence

A new technique of analyzing brain patterns appears to help people overcome fear and build self-confidence.

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http://ift.tt/2h9DtOF

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

A Kobe University research team has pinpointed the mechanism underlying astrocyte-mediated restoration of brain tissue after an injury. This could lead to new treatments that encourage regeneration by limiting damage to neurons incurred by reduced blood supply or trauma.

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Rutgers expert shares tips for Alzheimer’s and dementia caregiving during the holidays

Rutgers expert shares tips for Alzheimer’s and dementia caregiving during the holidays:

Dementia Big
The holidays can be an especially challenging time for family caregivers of people with dementia or Alzheimer’s disease.

http://ift.tt/2h9KoYg

Frequent sauna bathing protects men against dementia

Frequent sauna bathing protects men against dementia:

Dementia Big
Frequent sauna bathing can reduce the risk of dementia, according to a recent study carried out at the University of Eastern Finland. In a 20-year follow-up, men taking a sauna four to seven times a week were 66 percent less likely to be diagnosed with dementia than those taking a sauna once a week. The association between sauna bathing and dementia risk has not been previously investigated.

http://ift.tt/2gTieoc

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury:

Dementia Big
A Kobe University research team has pinpointed the mechanism underlying astrocyte-mediated restoration of brain tissue after an injury. This could lead to new treatments that encourage regeneration by limiting damage to neurons incurred by reduced blood supply or trauma.

http://ift.tt/2h9DfqS

New approach to analyzing brain patterns appears to help reduce people’s fear, build confidence

New approach to analyzing brain patterns appears to help reduce people’s fear, build confidence:

Dementia Big
A new technique of analyzing brain patterns appears to help people overcome fear and build self-confidence.

http://ift.tt/2gTfEia

Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Scientists discover possible way to stop activation of proteins known to cause age-related diseases:

Dementia Big
Researchers at the University of Surrey, in collaboration with the Universities of Reading and Cologne, and the Royal Berkshire Hospital, have discovered that it is possible to stop the activation of a group of proteins (NADPH Oxidase) known to cause most of the diseases of ageing.

http://ift.tt/2h9DdPM

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

In Alzheimer’s research, one particular protein looms large: plaque-forming amyloid-beta. Yet doctors now recognize that plaques can accumulate decades before symptoms appear. Recent clinical trials aimed at controlling or removing amyloid-beta have largely been disappointing.

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People with protein in urine more likely to develop memory problems, dementia

People who have protein in their urine, which is a sign of kidney problems, may also be more likely to later develop problems with thinking and memory skills or even dementia, according to a meta-analysis published in the December 14, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

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http://ift.tt/2hSOpQw

Early signs of Alzheimer's detected in cerebrospinal fluid

Little is known about the role of the brain’s immune system in Alzheimer’s disease. Researchers at the Munich site of the German Center for Neurodegenerative Diseases (DZNE) and the hospital of the Ludwig Maximilian University (LMU) Munich have now found an early immune response in individuals with a genetic predisposition to Alzheimer’s: their brain’s showed abnormal immune reactions as early as about seven years before the expected onset of dementia. These results demonstrate that in cases of Alzheimer’s, inflammatory processes in the brain evolve dynamically and are precursors of dementia. These immune responses can be detected by means of a protein in the cerebrospinal fluid, offering physicians the possibility to trace the progression of the disease. The study results are published in the journal Science Translational Medicine.

from Dementia Big http://ift.tt/2hpzm3Y via alcoholic dementia

http://ift.tt/2gPMIG1

Antipsychotic drug use linked to 60% increased risk of mortality among people with Alzheimer's disease

Antipsychotic drug use is associated with a 60 percent increased risk of mortality among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland.

from Dementia Big http://ift.tt/2hlivPP via alcoholic dementia

http://ift.tt/2hSVel5

Brain exercise and training program to improve mind and body wellness in individuals with mild cognitive impairment

Individuals with mild cognitive impairment have a new resource in Pittsburgh with the recently established Brain Training and Exercise (BRiTE) mind and body wellness program, developed by a team of clinicians and scientists at the University of Pittsburgh with expertise in cognition and behavior. The program works to stimulate the brain and body of those with known or suspected cognitive impairment with the goal of improving overall health and wellness.

from Dementia Big http://ift.tt/2hptCaA via alcoholic dementia

http://ift.tt/2gPPon2

Technological advancements in hearing implants

Hearing aids capture sound, make the sound louder and then send the sound down the ear canal, through the middle ear to the inner ear where the hearing nerves are located. They are most beneficial for people with mild to moderate hearing loss…

from Dementia Big http://ift.tt/2gZJvRR via alcoholic dementia

http://ift.tt/2hSYqxl

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

Alzheimer's: Proteomics gives clues toward alternatives to amyloid:

Dementia Big
In Alzheimer’s research, one particular protein looms large: plaque-forming amyloid-beta. Yet doctors now recognize that plaques can accumulate decades before symptoms appear. Recent clinical trials aimed at controlling or removing amyloid-beta have largely been disappointing.

http://ift.tt/2gPSRSy

People with protein in urine more likely to develop memory problems, dementia

People with protein in urine more likely to develop memory problems, dementia:

Dementia Big
People who have protein in their urine, which is a sign of kidney problems, may also be more likely to later develop problems with thinking and memory skills or even dementia, according to a meta-analysis published in the December 14, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

http://ift.tt/2hSN502

Early signs of Alzheimer's detected in cerebrospinal fluid

Early signs of Alzheimer's detected in cerebrospinal fluid:

Dementia Big
Little is known about the role of the brain’s immune system in Alzheimer’s disease. Researchers at the Munich site of the German Center for Neurodegenerative Diseases (DZNE) and the hospital of the Ludwig Maximilian University (LMU) Munich have now found an early immune response in individuals with a genetic predisposition to Alzheimer’s: their brain’s showed abnormal immune reactions as early as about seven years before the expected onset of dementia. These results demonstrate that in cases of Alzheimer’s, inflammatory processes in the brain evolve dynamically and are precursors of dementia. These immune responses can be detected by means of a protein in the cerebrospinal fluid, offering physicians the possibility to trace the progression of the disease. The study results are published in the journal Science Translational Medicine.

http://ift.tt/2gPOqqK

Antipsychotic drug use linked to 60% increased risk of mortality among people with Alzheimer's disease

Antipsychotic drug use linked to 60% increased risk of mortality among people with Alzheimer's disease:

Dementia Big
Antipsychotic drug use is associated with a 60 percent increased risk of mortality among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland.

http://ift.tt/2hSVDnH

Brain exercise and training program to improve mind and body wellness in individuals with mild cognitive impairment

Brain exercise and training program to improve mind and body wellness in individuals with mild cognitive impairment:

Dementia Big
Individuals with mild cognitive impairment have a new resource in Pittsburgh with the recently established Brain Training and Exercise (BRiTE) mind and body wellness program, developed by a team of clinicians and scientists at the University of Pittsburgh with expertise in cognition and behavior. The program works to stimulate the brain and body of those with known or suspected cognitive impairment with the goal of improving overall health and wellness.

http://ift.tt/2gPJKS2

Technological advancements in hearing implants

Technological advancements in hearing implants:

Dementia Big
Hearing aids capture sound, make the sound louder and then send the sound down the ear canal, through the middle ear to the inner ear where the hearing nerves are located. They are most beneficial for people with mild to moderate hearing loss…

http://ift.tt/2hSTU1S

Using herpes drugs to slow down Alzheimer's disease could become reality

The first clinical study to investigate if herpes virus drugs can have an effect on fundamental Alzheimer’s disease processes has been launched at Umeå University in Sweden. The research group has previously demonstrated a correlation between herpes virus infection and an increased risk of Alzheimer’s disease.

from Dementia Big http://ift.tt/2hsDkZY via alcoholic dementia

http://ift.tt/2gzZ0z3

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing the risk of Alzheimer’s disease, a University of Southern California-led study of Medicare data reveals.

from Dementia Big http://ift.tt/2gZpVW3 via alcoholic dementia

http://ift.tt/2hEfQla

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk:

Dementia Big
Common anti-cholesterol drugs show promise for reducing the risk of Alzheimer’s disease, a University of Southern California-led study of Medicare data reveals.

http://ift.tt/2hl3BJd

Using herpes drugs to slow down Alzheimer's disease could become reality

Using herpes drugs to slow down Alzheimer's disease could become reality:

Dementia Big
The first clinical study to investigate if herpes virus drugs can have an effect on fundamental Alzheimer’s disease processes has been launched at Umeå University in Sweden. The research group has previously demonstrated a correlation between herpes virus infection and an increased risk of Alzheimer’s disease.

http://ift.tt/2hvTHTp

Would you take a free predictive test for Alzheimer's disease?

Three-quarters of people aged 65 and over in the US would take a test telling them they were going to develop Alzheimer’s disease if such a test existed, according to research published in the open access journal Alzheimer’s Research and Therapy.

from Dementia Big http://ift.tt/2hniI5q via alcoholic dementia

http://ift.tt/2guQIrX

Why are some people immune to age-related cognitive decline?

Emily Rogalski, ‘07 PhD, is part of a team of scientists taking a glass half-full approach to studying cognitive aging. Instead of focusing on factors that can lead to dementia and neurodegenerative disease as people grow older, they concentrate on the factors that can protect memory. They do this by investigating seniors in their 80s, 90s and beyond who have remarkable memory power, a tiny subset of the population they call SuperAgers.

from Dementia Big http://ift.tt/2houXfc via alcoholic dementia

http://ift.tt/2hygCA4

The first-in-man clinical trial targeting Alzheimer's Tau protein

For the first time, targeting the other feature of Alzheimer’s disease, tau, has given fruitful results. In an unprecedented study, active vaccination in humans has resulted in a favorable immune response in 29 out of the 30 patients with only minor side effects.

from Dementia Big http://ift.tt/2hoslOk via alcoholic dementia

http://ift.tt/2guKc4L

Are cholesterol-lowering statins associated with reduced Alzheimer risk?

An analysis of Medicare data suggests that high use of cholesterol-lowering statins was associated with a reduced risk for Alzheimer disease but that reduction in risk varied by type of statin and race/ethnicity, findings that must be confirmed in clinical trials, according to a new article published online by JAMA Neurology.

from Dementia Big http://ift.tt/2hnbbnk via alcoholic dementia

http://ift.tt/2hyelVG

Antipsychotic drug use increases risk of mortality among persons with Alzheimer's disease

Antipsychotic drug use is associated with a 60 percent increased risk of mortality among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland. The risk was highest at the beginning of drug use and remained increased in long-term use. Use of two or more antipsychotic drugs concomitantly was associated with almost two times higher risk of mortality than monotherapy. The results were published in the Journal of Alzheimer’s Disease.

from Dementia Big http://ift.tt/2hnl8kk via alcoholic dementia

http://ift.tt/2guEXln

Would you take a free predictive test for Alzheimer's disease?

Would you take a free predictive test for Alzheimer's disease?:

Dementia Big
Three-quarters of people aged 65 and over in the US would take a test telling them they were going to develop Alzheimer’s disease if such a test existed, according to research published in the open access journal Alzheimer’s Research and Therapy.

http://ift.tt/2hybJah

Why are some people immune to age-related cognitive decline?

Why are some people immune to age-related cognitive decline?:

Dementia Big
Emily Rogalski, ‘07 PhD, is part of a team of scientists taking a glass half-full approach to studying cognitive aging. Instead of focusing on factors that can lead to dementia and neurodegenerative disease as people grow older, they concentrate on the factors that can protect memory. They do this by investigating seniors in their 80s, 90s and beyond who have remarkable memory power, a tiny subset of the population they call SuperAgers.

http://ift.tt/2guJhkM

The first-in-man clinical trial targeting Alzheimer's Tau protein

The first-in-man clinical trial targeting Alzheimer's Tau protein:

Dementia Big
For the first time, targeting the other feature of Alzheimer’s disease, tau, has given fruitful results. In an unprecedented study, active vaccination in humans has resulted in a favorable immune response in 29 out of the 30 patients with only minor side effects.

http://ift.tt/2hye30V

Are cholesterol-lowering statins associated with reduced Alzheimer risk?

Are cholesterol-lowering statins associated with reduced Alzheimer risk?:

Dementia Big
An analysis of Medicare data suggests that high use of cholesterol-lowering statins was associated with a reduced risk for Alzheimer disease but that reduction in risk varied by type of statin and race/ethnicity, findings that must be confirmed in clinical trials, according to a new article published online by JAMA Neurology.

http://ift.tt/2guy0kp

Antipsychotic drug use increases risk of mortality among persons with Alzheimer's disease

Antipsychotic drug use increases risk of mortality among persons with Alzheimer's disease:

Dementia Big
Antipsychotic drug use is associated with a 60 percent increased risk of mortality among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland. The risk was highest at the beginning of drug use and remained increased in long-term use. Use of two or more antipsychotic drugs concomitantly was associated with almost two times higher risk of mortality than monotherapy. The results were published in the Journal of Alzheimer’s Disease.

http://ift.tt/2hyfSez

The Vascular Impairment of Cognition Classification Consensus Study

The Vascular Impairment of Cognition Classification Consensus Study:

Dementia Big
Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment.

http://ift.tt/2hmp02I

The Vascular Impairment of Cognition Classification Consensus Study

Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment.

from Dementia Big http://ift.tt/2gnmwPL via alcoholic dementia

http://ift.tt/2gAwQqD

Glaucoma drug may have potential to treat Alzheimer's disease

Glaucoma drug may have potential to treat Alzheimer's disease:

Dementia Big
A drug which is used to treat the common eye disease glaucoma may have potential as a treatment for Alzheimer’s disease, according to scientists at UCL.

http://ift.tt/2hfJexu

Musica Humana: Innovative program highlights inspiring role of music in human thought and memory

Musica Humana: Innovative program highlights inspiring role of music in human thought and memory:

Dementia Big
According to renowned neurologist Oliver Sacks, “music can move us to the heights or depths of emotion, but the power of music goes much further.”

http://ift.tt/2glx3uo

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression:

Dementia Big
We hypothesized that common Alzheimer’s disease (AD)-associated variants within the triggering receptor expressed on myeloid (TREM) gene cluster influence disease through gene expression.

http://ift.tt/2hfNop3

Glaucoma drug may have potential to treat Alzheimer's disease

A drug which is used to treat the common eye disease glaucoma may have potential as a treatment for Alzheimer’s disease, according to scientists at UCL.

from Dementia Big http://ift.tt/2h4wmKl via alcoholic dementia

http://ift.tt/2glwFMy

Musica Humana: Innovative program highlights inspiring role of music in human thought and memory

According to renowned neurologist Oliver Sacks, “music can move us to the heights or depths of emotion, but the power of music goes much further.”

from Dementia Big http://ift.tt/2gjilsN via alcoholic dementia

http://ift.tt/2hfJdcU

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

We hypothesized that common Alzheimer’s disease (AD)-associated variants within the triggering receptor expressed on myeloid (TREM) gene cluster influence disease through gene expression.

from Dementia Big http://ift.tt/2ghRkWM via alcoholic dementia

http://ift.tt/2glwqB5

Honeybee brain helps unravel mystery behind long-term memory formation

Honeybee brain helps unravel mystery behind long-term memory formation:

Dementia Big
A breakdown of memory processes in humans can lead to conditions such as Alzheimer’s and dementia.

http://ift.tt/2ghOqBv

Alzheimer's patients' use of painkilling patches cause for concern

Alzheimer's patients' use of painkilling patches cause for concern:

Dementia Big
(HealthDay)—Long-term use of powerful opioid painkillers may be common among Alzheimer’s disease patients and could be a cause for concern, researchers report.

http://ift.tt/2hcddEh

New tool to help predict dementia risk in older people

New tool to help predict dementia risk in older people:

Dementia Big
Preventing dementia is a major public health priority worldwide, and intense work is being conducted to formulate effective preventive strategies. Healthy lifestyle changes may help prevent cognitive decline and dementia, but the challenge is to detect early on those who are most at risk and to choose the most relevant preventive measures.

http://ift.tt/2ghQ7Pp

New stem cell research project to replicate brain's neural networks using 3D nanoprinting

New stem cell research project to replicate brain's neural networks using 3D nanoprinting:

Dementia Big
Aston University has launched MESO-BRAIN, a major stem cell research project which it hopes will develop three-dimensional (3D) nanoprinting techniques that can be used to replicate the brain’s neural networks.​

http://ift.tt/2hc8Zwa

High adolescent BMI could impact cognitive function in midlife

High adolescent BMI could impact cognitive function in midlife:

Dementia Big
Scientists at the Hebrew University of Jerusalem have found that higher Body Mass Index (BMI), if it begins in adolescence, can affect cognitive function in midlife. However, the effect appears to be restricted to adults who had lower socioeconomic position as children.

http://ift.tt/2ghMRTQ

Novel machine learning approach could help predict dementia risk in cognitively healthy older people

Novel machine learning approach could help predict dementia risk in cognitively healthy older people:

Dementia Big
A machine learning method analyzing large amounts of health information has potential in assessing the risk of cognitively healthy older people for later dementia, according to research published in the Journal of Alzheimer’s Disease. The new risk assessment tool also presents the individual risk profile in a quickly interpretable visual form.

http://ift.tt/2hcaMl6

Higher BMI in adolescence may affect cognitive function in midlife

Higher BMI in adolescence may affect cognitive function in midlife:

Dementia Big
Overweight and obesity in adolescents have increased substantially in recent decades, and today affect a third of the adolescent population in some developed countries. While the dangers posed by high adult BMI on cognitive function in later life have been documented, the association of adolescent BMI with cognitive function in midlife has not yet been reported. (BMI, or Body Mass Index, is a calculation of a person’s weight in kilograms divided by the square of their height in meters.)

http://ift.tt/2ghQWHD

Scientists uncover potential driver of age- and Alzheimer's-related memory loss

Scientists uncover potential driver of age- and Alzheimer's-related memory loss:

Dementia Big
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer’s. They found that reduced levels of a protein called Rheb result in spontaneous symptoms of memory loss in animal models and are linked to increased levels of another protein known to be elevated in the brains of Alzheimer’s disease patients.

http://ift.tt/2hc8ZfE

Lost and found: Japan tags dementia sufferers with barcodes

Lost and found: Japan tags dementia sufferers with barcodes:

Dementia Big
A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.

http://ift.tt/2ghPrcI

Study highlights importance of intimate, social relationships for older adults in assisted-living facilities

Study highlights importance of intimate, social relationships for older adults in assisted-living facilities:

Dementia Big
Intimate and social relationships remain important for older adults residing in assisted-living facilities, according to a recent study.

http://ift.tt/2hc8X7v

Brain activity of healthy older adults could help predict risk of falling

Brain activity of healthy older adults could help predict risk of falling:

Dementia Big
Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence.

http://ift.tt/2ghOxNk

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits:

Dementia Big
Scientists from the Florida campus of The Scripps Research Institute have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer’s.

http://ift.tt/2hcdTcK

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials:

Dementia Big
A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease following publication of research findings today in the journal Science Translational Medicine.

http://ift.tt/2ghPSDF

Unique visual stimulation may be new treatment for Alzheimer's

Unique visual stimulation may be new treatment for Alzheimer's:

Dementia Big
Using LED lights flickering at a specific frequency, MIT researchers have shown that they can substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the visual cortex of mice.

http://ift.tt/2hc76Qo

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease:

Dementia Big
Misfolded proteins associated with Parkinson’s disease were detected in cerebrospinal fluid by scientists at McGovern Medical School at The University of Texas Health Science Center at Houston, paving the way to development of a biochemical test to diagnosis the disease.

http://ift.tt/2ghJw7v

MAO is a possible Alzheimer's disease biomarker

MAO is a possible Alzheimer's disease biomarker:

Dementia Big
Alzheimer’s disease affects more than 35 million people, a number that is expected to increase in the coming years. Currently, Alzheimer’s diagnoses rely on clinical neuropathologic assessment of amyloid-β (Aβ) peptide aggregates (plaques) and neurofibrillary tangles. But in ACS Central Science, researchers reveal that an enzyme already implicated in a host of neural disorders could someday serve as a biomarker.

http://ift.tt/2hc3nCf

Alzheimer's patients' use of painkilling patches cause for concern

(HealthDay)—Long-term use of powerful opioid painkillers may be common among Alzheimer’s disease patients and could be a cause for concern, researchers report.

from Dementia Big http://ift.tt/2hlsp4P via alcoholic dementia

http://ift.tt/2hbeVrC

Honeybee brain helps unravel mystery behind long-term memory formation

A breakdown of memory processes in humans can lead to conditions such as Alzheimer’s and dementia.

from Dementia Big http://ift.tt/2h8WfGs via alcoholic dementia

http://ift.tt/2gglFjH

New tool to help predict dementia risk in older people

Preventing dementia is a major public health priority worldwide, and intense work is being conducted to formulate effective preventive strategies. Healthy lifestyle changes may help prevent cognitive decline and dementia, but the challenge is to detect early on those who are most at risk and to choose the most relevant preventive measures.

from Dementia Big http://ift.tt/2gHpY8M via alcoholic dementia

http://ift.tt/2hb7PDw

New stem cell research project to replicate brain's neural networks using 3D nanoprinting

Aston University has launched MESO-BRAIN, a major stem cell research project which it hopes will develop three-dimensional (3D) nanoprinting techniques that can be used to replicate the brain’s neural networks.​

from Dementia Big http://ift.tt/2goEowG via alcoholic dementia

http://ift.tt/2ggxpCP

High adolescent BMI could impact cognitive function in midlife

Scientists at the Hebrew University of Jerusalem have found that higher Body Mass Index (BMI), if it begins in adolescence, can affect cognitive function in midlife. However, the effect appears to be restricted to adults who had lower socioeconomic position as children.

from Dementia Big http://ift.tt/2hojLyz via alcoholic dementia

http://ift.tt/2hbebmB

Novel machine learning approach could help predict dementia risk in cognitively healthy older people

A machine learning method analyzing large amounts of health information has potential in assessing the risk of cognitively healthy older people for later dementia, according to research published in the Journal of Alzheimer’s Disease. The new risk assessment tool also presents the individual risk profile in a quickly interpretable visual form.

from Dementia Big http://ift.tt/2ho1DEQ via alcoholic dementia

http://ift.tt/2ggrPjG

Higher BMI in adolescence may affect cognitive function in midlife

Overweight and obesity in adolescents have increased substantially in recent decades, and today affect a third of the adolescent population in some developed countries. While the dangers posed by high adult BMI on cognitive function in later life have been documented, the association of adolescent BMI with cognitive function in midlife has not yet been reported. (BMI, or Body Mass Index, is a calculation of a person’s weight in kilograms divided by the square of their height in meters.)

from Dementia Big http://ift.tt/2h92BbJ via alcoholic dementia

http://ift.tt/2hbctl2

Scientists uncover potential driver of age- and Alzheimer's-related memory loss

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer’s. They found that reduced levels of a protein called Rheb result in spontaneous symptoms of memory loss in animal models and are linked to increased levels of another protein known to be elevated in the brains of Alzheimer’s disease patients.

from Dementia Big http://ift.tt/2h8WELC via alcoholic dementia

http://ift.tt/2ggA4fI

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.

from Dementia Big http://ift.tt/2hlkrbI via alcoholic dementia

http://ift.tt/2hbd5al

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease following publication of research findings today in the journal Science Translational Medicine.

from Dementia Big http://ift.tt/2gcLPDO via alcoholic dementia

http://ift.tt/2ggtJkl

Unique visual stimulation may be new treatment for Alzheimer's

Using LED lights flickering at a specific frequency, MIT researchers have shown that they can substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the visual cortex of mice.

from Dementia Big http://ift.tt/2gb8RzG via alcoholic dementia

http://ift.tt/2hba9ur

Brain activity of healthy older adults could help predict risk of falling

Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence.

from Dementia Big http://ift.tt/2h7XV5P via alcoholic dementia

http://ift.tt/2ggxnLd

Study highlights importance of intimate, social relationships for older adults in assisted-living facilities

Intimate and social relationships remain important for older adults residing in assisted-living facilities, according to a recent study.

from Dementia Big http://ift.tt/2gWHc4X via alcoholic dementia

http://ift.tt/2hbbdyx

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits

Scientists from the Florida campus of The Scripps Research Institute have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer’s.

from Dementia Big http://ift.tt/2gmaoRW via alcoholic dementia

http://ift.tt/2ggEUJS

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Misfolded proteins associated with Parkinson’s disease were detected in cerebrospinal fluid by scientists at McGovern Medical School at The University of Texas Health Science Center at Houston, paving the way to development of a biochemical test to diagnosis the disease.

from Dementia Big http://ift.tt/2gbiSYX via alcoholic dementia

http://ift.tt/2hbecqF

MAO is a possible Alzheimer's disease biomarker

Alzheimer’s disease affects more than 35 million people, a number that is expected to increase in the coming years. Currently, Alzheimer’s diagnoses rely on clinical neuropathologic assessment of amyloid-β (Aβ) peptide aggregates (plaques) and neurofibrillary tangles. But in ACS Central Science, researchers reveal that an enzyme already implicated in a host of neural disorders could someday serve as a biomarker.

from Dementia Big http://ift.tt/2gXVguN via alcoholic dementia

http://ift.tt/2ggAQt0

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

The hip fracture risk factors are generally similar among those with and without Alzheimer’s disease, according to a recent study from the University of Eastern Finland. However, the incidence of hip fracture is higher among those with Alzheimer’s disease, regardless of other characteristics. Alzheimer’s disease itself appears to be such a significant risk factor for hip fracture that the relative impact of other risk factors is considerably smaller among those with Alzheimer’s disease.

from Dementia Big http://ift.tt/2h2KHnP via alcoholic dementia

http://ift.tt/2hirZIv

Research underscores need for targeted interventions to prevent hip fractures among dementia patients

The hip fracture risk factors are generally similar among those with and without Alzheimer’s disease, according to a recent study from the University of Eastern Finland.

from Dementia Big http://ift.tt/2h1TRB8 via alcoholic dementia

http://ift.tt/2gTrreU

Heart disease protein linked to brain damage

Levels of a protein in the blood associated with heart disease are also linked to early-stage brain damage, according to a study appearing online in the journal Radiology.

from Dementia Big http://ift.tt/2gkalX0 via alcoholic dementia

http://ift.tt/2gTrqHS

Study shows how speed information reaches the brain's navigation center

Similar neural pathways exist in humans. They are known to be damaged by Alzheimer’s disease - a possible explanation why spatial orientation is frequently impaired in this form of dementia.

from Dementia Big http://ift.tt/2hfDb8n via alcoholic dementia

http://ift.tt/2hiytqt

Colonic diverticular disease may increase dementia risk

(HealthDay)—Patients with colonic diverticular disease may be at an increased risk for dementia, according to a study published Nov. 23 in the Journal of Gastroenterology and Hepatology.

from Dementia Big http://ift.tt/2g7Lfr3 via alcoholic dementia

http://ift.tt/2hiCUlf

Potentially unsafe med scripts up for dual users with dementia

(HealthDay)—For veterans with dementia, Veterans Affairs (VA)-Medicare Part D (dual-system) users have increased rates of potentially unsafe medication (PUM) prescribing, according to a study published online Dec. 6 in the Annals of Internal Medicine.

from Dementia Big http://ift.tt/2g72hdG via alcoholic dementia

http://ift.tt/2gTx5Oi

Early signs of Alzheimer's disease identified

Researchers from the University of Aberdeen have detected key changes in the brains of people with Alzheimer’s disease.

from Dementia Big http://ift.tt/2gM6imP via alcoholic dementia

http://ift.tt/2gTsgV5

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement

The overall goal of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) is to validate biomarkers for Alzheimer’s disease (AD) clinical trials. ADNI-3, which began on August 1, 2016, is a 5-year renewal of the current ADNI-2 study.

from Dementia Big http://ift.tt/2gWvWTs via alcoholic dementia

http://ift.tt/2his0Mz

Subscriber Information

People across the country have been recognised for their ‘remarkable’ efforts to make life better for people with dementia at Alzheimer’s Society’s 2016 Dementia Friendly Awards.

from Dementia Big http://ift.tt/2h2EdWg via alcoholic dementia
http://ift.tt/2gTx5xM

Contents

from Dementia Big http://ift.tt/2gk0bWr via alcoholic dementia

http://ift.tt/2hizS0o

Editorial Board

from Dementia Big http://ift.tt/2h2LhlI via alcoholic dementia

http://ift.tt/2hiy4of

Alzheimer's Association Update

In a single day, the Alzheimer’s science community lost two pioneering researchers, Allen Roses, MD, who led the team that in 1992 identified Apolipoprotein ε4 as a major risk gene for Alzheimer’s disease (AD), and Dale Schenk, PhD, whose seminal work in immunotherapy led to the first clinical trial of a beta-amyloid vaccine for AD. Both men died Friday, September 30, 2016.

from Dementia Big http://ift.tt/2gk761G via alcoholic dementia

http://ift.tt/2hisZfo

Medical and Scientific Advisory Council

In a single day, the Alzheimer’s science community lost two pioneering researchers, Allen Roses, MD, who led the team that in 1992 identified Apolipoprotein ε4 as a major risk gene for Alzheimer’s disease (AD), and Dale Schenk, PhD, whose seminal work in immunotherapy led to the first clinical trial of a beta-amyloid vaccine for AD. Both men died Friday, September 30, 2016.

from Dementia Big http://ift.tt/2h2J8Gq via alcoholic dementia

http://ift.tt/2gTCHYC

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease:

Dementia Big
The hip fracture risk factors are generally similar among those with and without Alzheimer’s disease, according to a recent study from the University of Eastern Finland. However, the incidence of hip fracture is higher among those with Alzheimer’s disease, regardless of other characteristics. Alzheimer’s disease itself appears to be such a significant risk factor for hip fracture that the relative impact of other risk factors is considerably smaller among those with Alzheimer’s disease.

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Research underscores need for targeted interventions to prevent hip fractures among dementia patients

Research underscores need for targeted interventions to prevent hip fractures among dementia patients:

Dementia Big
The hip fracture risk factors are generally similar among those with and without Alzheimer’s disease, according to a recent study from the University of Eastern Finland.

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Study shows how speed information reaches the brain's navigation center

Study shows how speed information reaches the brain's navigation center:

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Similar neural pathways exist in humans. They are known to be damaged by Alzheimer’s disease - a possible explanation why spatial orientation is frequently impaired in this form of dementia.

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Colonic diverticular disease may increase dementia risk

Colonic diverticular disease may increase dementia risk:

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(HealthDay)—Patients with colonic diverticular disease may be at an increased risk for dementia, according to a study published Nov. 23 in the Journal of Gastroenterology and Hepatology.

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Heart disease protein linked to brain damage

Heart disease protein linked to brain damage:

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Levels of a protein in the blood associated with heart disease are also linked to early-stage brain damage, according to a study appearing online in the journal Radiology.

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Early signs of Alzheimer's disease identified

Early signs of Alzheimer's disease identified:

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Researchers from the University of Aberdeen have detected key changes in the brains of people with Alzheimer’s disease.

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Potentially unsafe med scripts up for dual users with dementia

Potentially unsafe med scripts up for dual users with dementia:

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(HealthDay)—For veterans with dementia, Veterans Affairs (VA)-Medicare Part D (dual-system) users have increased rates of potentially unsafe medication (PUM) prescribing, according to a study published online Dec. 6 in the Annals of Internal Medicine.

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Research validates effectiveness of world-first dental vaccine

Research validates effectiveness of world-first dental vaccine:

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A world-first vaccine developed by Melbourne scientists, which could eliminate or at least reduce the need for surgery and antibiotics for severe gum disease, has been validated by research published this weekend in a leading international journal.

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Clinicians should address needs of family caregivers of persons with dementia

Clinicians should address needs of family caregivers of persons with dementia:

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More than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current healthcare environment and reimbursement models emphasize obligations toward individual patients, preventing clinicians from reaching out to these caregivers to assess their needs and provide care.

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Addressing dementia's identity crisis

Addressing dementia's identity crisis:

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Dementia should be understood more as a disability, rather than a disease, with a greater emphasis placed on supporting those who care for people with the condition, according to a new report from the Social Care Workforce Research Unit, part of the Policy Institute, King’s College London.

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Women with dementia receive less medical attention

Women with dementia receive less medical attention:

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Women with dementia have fewer visits to the GP, receive less health monitoring and take more potentially harmful medication than men with dementia, new UCL (University College London) research reveals.

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Women with dementia receive less health monitoring than men, UCL research reveals

Women with dementia receive less health monitoring than men, UCL research reveals:

Dementia Big
Women with dementia have fewer visits to the GP, receive less health monitoring and take more potentially harmful medication than men with dementia, new UCL (University College London) research reveals.

http://ift.tt/2g3jWmm

Research validates effectiveness of world-first dental vaccine

A world-first vaccine developed by Melbourne scientists, which could eliminate or at least reduce the need for surgery and antibiotics for severe gum disease, has been validated by research published this weekend in a leading international journal.

from Dementia Big http://ift.tt/2hbp8Fd via alcoholic dementia

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Clinicians should address needs of family caregivers of persons with dementia

More than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current healthcare environment and reimbursement models emphasize obligations toward individual patients, preventing clinicians from reaching out to these caregivers to assess their needs and provide care.

from Dementia Big http://ift.tt/2gJt3rL via alcoholic dementia

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Addressing dementia's identity crisis

Dementia should be understood more as a disability, rather than a disease, with a greater emphasis placed on supporting those who care for people with the condition, according to a new report from the Social Care Workforce Research Unit, part of the Policy Institute, King’s College London.

from Dementia Big http://ift.tt/2g0263F via alcoholic dementia

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Women with dementia receive less medical attention

Women with dementia have fewer visits to the GP, receive less health monitoring and take more potentially harmful medication than men with dementia, new UCL (University College London) research reveals.

from Dementia Big http://ift.tt/2h4YNnS via alcoholic dementia

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Women with dementia receive less health monitoring than men, UCL research reveals

Women with dementia have fewer visits to the GP, receive less health monitoring and take more potentially harmful medication than men with dementia, new UCL (University College London) research reveals.

from Dementia Big http://ift.tt/2gqRrLJ via alcoholic dementia

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OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer’s disease.

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Study suggests possible new target for treating and preventing Alzheimer's

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer’s disease.

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Researchers identify link between brain and bone in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer’s disease (AD). The study, titled “Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer’s Disease,” is led by Christine Dengler-Crish, Ph.D., assistant professor of pharmaceutical sciences, and anatomy and neurobiology, and will be published in the upcoming issue of the Journal of Alzheimer’s Disease, an international multidisciplinary journal that reports progress in understanding the causes, symptoms, and treatment of Alzheimer’s.

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Researcher claims attending the symphony reverses cognitive decline in people with dementia

A program that delivers the gift of live classical music to people with dementia has been shown to have strikingly positive effects on mood, cognitive function and relationships.

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How old is your heart?

There have been a number of ways to measure the biological health and age of your heart, which has been done conventionally in the past. Blood pressure is one indicator. Other risk indicators include family history of heart disease, level of cholesterol and exercise testing, where you can get heart rate…

from Dementia Big http://ift.tt/2fIJvJs via alcoholic dementia

http://ift.tt/2gSl5tg

New global network to explore link between genes and environmental factors to tackle health challenges

A new global network linking leading research centres across the world has launched today to tackle some of the most pressing global health challenges of our time such as autism, cancer, diabetes and dementia.

from Dementia Big http://ift.tt/2gOtyNP via alcoholic dementia

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OHSU scientists identify potential target for preventing and treating Alzheimer's disease

OHSU scientists identify potential target for preventing and treating Alzheimer's disease:

Dementia Big
A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer’s disease.

http://ift.tt/2fMd5xE

Study suggests possible new target for treating and preventing Alzheimer's

Study suggests possible new target for treating and preventing Alzheimer's:

Dementia Big
A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer’s disease.

http://ift.tt/2gSlQCh

Researcher claims attending the symphony reverses cognitive decline in people with dementia

Researcher claims attending the symphony reverses cognitive decline in people with dementia:

Dementia Big
A program that delivers the gift of live classical music to people with dementia has been shown to have strikingly positive effects on mood, cognitive function and relationships.

http://ift.tt/2fMcMDe

How old is your heart?

How old is your heart?:

Dementia Big
There have been a number of ways to measure the biological health and age of your heart, which has been done conventionally in the past. Blood pressure is one indicator. Other risk indicators include family history of heart disease, level of cholesterol and exercise testing, where you can get heart rate…

http://ift.tt/2gSkt6O

Researchers identify link between brain and bone in Alzheimer's disease

Researchers identify link between brain and bone in Alzheimer's disease:

Dementia Big
Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer’s disease (AD). The study, titled “Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer’s Disease,” is led by Christine Dengler-Crish, Ph.D., assistant professor of pharmaceutical sciences, and anatomy and neurobiology, and will be published in the upcoming issue of the Journal of Alzheimer’s Disease, an international multidisciplinary journal that reports progress in understanding the causes, symptoms, and treatment of Alzheimer’s.

http://ift.tt/2fM8bkn

New global network to explore link between genes and environmental factors to tackle health challenges

New global network to explore link between genes and environmental factors to tackle health challenges:

Dementia Big
A new global network linking leading research centres across the world has launched today to tackle some of the most pressing global health challenges of our time such as autism, cancer, diabetes and dementia.

http://ift.tt/2gSeWgr