Friday, March 2, 2018

Study confirms the link between hearing loss and dementia in older adults

On World Hearing Day, the BIHIMA highlight an important new study into the link between hearing loss and the risk of dementia in older adults.



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Female sex hormones and mechanics of memory

Dr. Karyn Frick was puzzled. Her two-year study, begun with funding from Women’s Health Research at Yale in 2005, found that long-term treatment with the sex hormones estrogen and progesterone did not improve memory as anticipated.

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UAB scientists explore gene therapy for frontotemporal dementia

Gene therapy has shown promise for treating a neurodegenerative disease known as frontotemporal dementia and a related condition called neuronal ceroid lipofuscinosis, according to new findings presented in the Journal of Neuroscience by researchers from the University of Alabama at Birmingham.

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A tale of love, family conflict and battles over care for an aging mother

“Edith + Eddie,” a short documentary vying for an Academy Award Sunday, is a gripping look at a couple in their 90s caught up in an intense family conflict over caring for an aging parent.

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Traumatic brain injuries may increase risk of Alzheimer’s disease earlier in life

Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer’s disease earlier in life, according to a study from UT Southwestern’s Peter O'Donnell Jr. Brain Institute.

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Stem-cell study points to new approach to Alzheimer's disease

Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer’s disease, results of a new study suggest.

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Women with Alzheimer's lose their verbal communication skills quicker than men

A new research review, conducted by academics at the University of Hertfordshire, has identified that the cognitive areas where women usually have the upper hand over men, such as verbal communication, are those quickest to decline in women as the Alzheimer’s disease progresses.

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Brain injury may boost risk of Alzheimer's earlier in life

Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer’s disease earlier in life, according to a study from UT Southwestern’s Peter O'Donnell Jr. Brain Institute.

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Changes in the eye connected to a decline in memory

Researchers in the US have found that changes in the blood vessels of the eye are associated with a greater decline in people’s memory and language skills over a 20-year period. Their findings are published today in the scientific journal, Neurology.

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Study sheds light on a key protein associated with brain diseases and dementia

A new study has increased understanding of the connection between angiogenin and neurological disorders such as ALS and Fronto-temporal dementia.

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http://ift.tt/2CVc5xL

Female sex hormones and mechanics of memory

Female sex hormones and mechanics of memory:

Dementia Big
Dr. Karyn Frick was puzzled. Her two-year study, begun with funding from Women’s Health Research at Yale in 2005, found that long-term treatment with the sex hormones estrogen and progesterone did not improve memory as anticipated.


http://ift.tt/2oL8Io8

UAB scientists explore gene therapy for frontotemporal dementia

UAB scientists explore gene therapy for frontotemporal dementia:

Dementia Big
Gene therapy has shown promise for treating a neurodegenerative disease known as frontotemporal dementia and a related condition called neuronal ceroid lipofuscinosis, according to new findings presented in the Journal of Neuroscience by researchers from the University of Alabama at Birmingham.


http://ift.tt/2HYlb0v

A tale of love, family conflict and battles over care for an aging mother

A tale of love, family conflict and battles over care for an aging mother:

Dementia Big
“Edith + Eddie,” a short documentary vying for an Academy Award Sunday, is a gripping look at a couple in their 90s caught up in an intense family conflict over caring for an aging parent.


http://ift.tt/2oKcKNO

Traumatic brain injuries may increase risk of Alzheimer’s disease earlier in life

Traumatic brain injuries may increase risk of Alzheimer’s disease earlier in life:

Dementia Big
Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer’s disease earlier in life, according to a study from UT Southwestern’s Peter O'Donnell Jr. Brain Institute.


http://ift.tt/2HYl8ll

Stem-cell study points to new approach to Alzheimer's disease

Stem-cell study points to new approach to Alzheimer's disease:

Dementia Big
Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer’s disease, results of a new study suggest.


http://ift.tt/2oIxuFs

Women with Alzheimer's lose their verbal communication skills quicker than men

Women with Alzheimer's lose their verbal communication skills quicker than men:

Dementia Big
A new research review, conducted by academics at the University of Hertfordshire, has identified that the cognitive areas where women usually have the upper hand over men, such as verbal communication, are those quickest to decline in women as the Alzheimer’s disease progresses.


http://ift.tt/2HYl1WX

Study sheds light on a key protein associated with brain diseases and dementia

Study sheds light on a key protein associated with brain diseases and dementia:

Dementia Big
A new study has increased understanding of the connection between angiogenin and neurological disorders such as ALS and Fronto-temporal dementia.


http://ift.tt/2oIxrJM

Brain injury may boost risk of Alzheimer's earlier in life

Brain injury may boost risk of Alzheimer's earlier in life:

Dementia Big
Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer’s disease earlier in life, according to a study from UT Southwestern’s Peter O'Donnell Jr. Brain Institute.


http://ift.tt/2HWY8mQ

Changes in the eye connected to a decline in memory

Changes in the eye connected to a decline in memory:

Dementia Big
Researchers in the US have found that changes in the blood vessels of the eye are associated with a greater decline in people’s memory and language skills over a 20-year period. Their findings are published today in the scientific journal, Neurology.


http://ift.tt/2oH8DSu

Thursday, March 1, 2018

New campaign launched for Utilities industry to become dementia-friendly

On 28 February 2018 we launched the first ever dementia-friendly utilities guide, asking businesses to unite against dementia and commit to better supporting customers affected by the condition.



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SACN report on diet and dementia risk - Alzheimer's Society comment

A report published yesterday (28 February) by the Scientific Advisory Committee on Nutrition (SACN) has suggested that there is little evidence of a link between diet and dementia risk.



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SACN report on diet and dementia risk - Alzheimer's Society comment

SACN report on diet and dementia risk - Alzheimer's Society comment:

Dementia Big
A report published yesterday (28 February) by the Scientific Advisory Committee on Nutrition (SACN) has suggested that there is little evidence of a link between diet and dementia risk.


http://ift.tt/2oIDUo1

New campaign launched for Utilities industry to become dementia-friendly

New campaign launched for Utilities industry to become dementia-friendly:

Dementia Big
On 28 February 2018 we launched the first ever dementia-friendly utilities guide, asking businesses to unite against dementia and commit to better supporting customers affected by the condition.


http://ift.tt/2HWgpAO

Free online tool to accelerate Alzheimer's treatment created by USC and top medical groups

Free online tool to accelerate Alzheimer's treatment created by USC and top medical groups:

Dementia Big
An online tool that helps older people monitor their brain health has been developed at the Keck School of Medicine of USC with other medical groups.


http://ift.tt/2HUef4s

Evaluation of tau phosphorylation-related targets for Alzheimer's treatment

Evaluation of tau phosphorylation-related targets for Alzheimer's treatment:

Dementia Big
InSysBio continues to investigate the mechanisms underlying Alzheimer’s disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. The QSP model describing the tau protein was published in PLOS ONE.


http://ift.tt/2oGzKx1

Tuesday, February 27, 2018

The onset of Alzheimer's disease: The importance of family history

You’re about to turn 60, and you’re fretting. Your mother has had Alzheimer’s disease since the age of 65. At what age will the disease strike you? A Canadian study published in JAMA Neurology shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer’s, the more likely they are to have amyloid plaques, the cause of the cognitive decline associated with the disease, in their brain.

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The onset of Alzheimer's disease: The importance of family history

The onset of Alzheimer's disease: The importance of family history:

Dementia Big
You’re about to turn 60, and you’re fretting. Your mother has had Alzheimer’s disease since the age of 65. At what age will the disease strike you? A Canadian study published in JAMA Neurology shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer’s, the more likely they are to have amyloid plaques, the cause of the cognitive decline associated with the disease, in their brain.


http://ift.tt/2ox3ygj

Monday, February 26, 2018

Trump’s perfect score on brain test spawns DIY cognitive exam

Trump’s perfect score on brain test spawns DIY cognitive exam:

Dementia Big
When Donald Trump aced a cognitive test in January, scores of people tried to take it, too, based mostly on media reports that invited them to match wits with the president.


http://ift.tt/2HPB4WX

Trump’s perfect score on brain test spawns DIY cognitive exam

When Donald Trump aced a cognitive test in January, scores of people tried to take it, too, based mostly on media reports that invited them to match wits with the president.

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http://ift.tt/2GOpp9P

Saturday, February 24, 2018

Older adults with dementia more likely to be readmitted to hospital after discharge

Older adults with dementia more likely to be readmitted to hospital after discharge:

Dementia Big
About 25 percent of older adults admitted to hospitals have dementia and are at increased risk for serious problems like in-hospital falls and delirium (the medical term for an abrupt, rapid change in mental function). As a result, older adults with dementia are more likely to do poorly during hospital stays compared to older adults without dementia.


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Older adults with dementia more likely to be readmitted to hospital after discharge

About 25 percent of older adults admitted to hospitals have dementia and are at increased risk for serious problems like in-hospital falls and delirium (the medical term for an abrupt, rapid change in mental function). As a result, older adults with dementia are more likely to do poorly during hospital stays compared to older adults without dementia.

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Friday, February 23, 2018

Dementia increases the risk of 30-day readmission to the hospital after discharge

About 25 percent of older adults admitted to hospitals have dementia and are at increased risk for serious problems like in-hospital falls and delirium (the medical term for an abrupt, rapid change in mental function). As a result, older adults with dementia are more likely to do poorly during hospital stays compared to older adults without dementia.

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Dementia increases the risk of 30-day readmission to the hospital after discharge

Dementia increases the risk of 30-day readmission to the hospital after discharge:

Dementia Big
About 25 percent of older adults admitted to hospitals have dementia and are at increased risk for serious problems like in-hospital falls and delirium (the medical term for an abrupt, rapid change in mental function). As a result, older adults with dementia are more likely to do poorly during hospital stays compared to older adults without dementia.


http://ift.tt/2EZ9Q1E

Cardiorespiratory fitness, white matter integrity tied to cognition

(HealthDay)—Cardiorespiratory fitness (CRF) is associated with better white matter (WM) fiber integrity in patients with mild cognitive impairment (MCI), according to a study published recently in the Journal of Alzheimer’s Disease.

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New intervention improves communication behaviors in couples affected by dementia

They do it with the best of intentions. “Do you remember our wedding day?” “Who is that person next to you in the picture?” For couples with decades of shared memories, a partner’s decline in the ability to communicate is one of the most frightening and frustrating consequences of Alzheimer’s disease and related dementias.

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http://ift.tt/2BLt8W8

Cardiorespiratory fitness, white matter integrity tied to cognition

Cardiorespiratory fitness, white matter integrity tied to cognition:

Dementia Big
(HealthDay)—Cardiorespiratory fitness (CRF) is associated with better white matter (WM) fiber integrity in patients with mild cognitive impairment (MCI), according to a study published recently in the Journal of Alzheimer’s Disease.


http://ift.tt/2sQsgwE

New intervention improves communication behaviors in couples affected by dementia

New intervention improves communication behaviors in couples affected by dementia:

Dementia Big
They do it with the best of intentions. “Do you remember our wedding day?” “Who is that person next to you in the picture?” For couples with decades of shared memories, a partner’s decline in the ability to communicate is one of the most frightening and frustrating consequences of Alzheimer’s disease and related dementias.


http://ift.tt/2F1j2mg

Thursday, February 22, 2018

Physical and mental multitasking may boost memory, study suggests

Performing memory training exercises at the same time as pedaling a stationary bike led to better gains in memory than doing the training exercises after working up a sweat, according to a 55-person study led by UCLA researchers. The findings suggest that exercise may temporarily make it easier for the brain to create new memories.

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Researchers explore how people with Alzheimer's disease use end-of-life medical services

Because people are now living longer and often healthier lives, the rate of some illnesses that are more likely to develop with age has risen. These illnesses include dementia. In fact, the number of us living with dementia was already 47 million worldwide in 2015. It could reach 131 million by 2050.

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Liquefied brain tissue after stroke may harm surviving brain, UA study finds

Scientists have known for years that the brain liquefies after a stroke. If cut off from blood and oxygen for a long enough period, a portion of the brain will die, slowly morphing from a hard, rubbery substance into liquid goop.

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http://ift.tt/2oibp0X

End-of-life hospital and healthcare use among older adults with Alzheimer's disease

Because people are now living longer and often healthier lives, the rate of some illnesses that are more likely to develop with age has risen. These illnesses include dementia. In fact, the number of us living with dementia was already 47 million worldwide in 2015. It could reach 131 million by 2050.

from Dementia Big http://ift.tt/2sGyUFI via alcoholic dementia


http://ift.tt/2BIBT3m

Physical and mental multitasking may boost memory, study suggests

Physical and mental multitasking may boost memory, study suggests:

Dementia Big
Performing memory training exercises at the same time as pedaling a stationary bike led to better gains in memory than doing the training exercises after working up a sweat, according to a 55-person study led by UCLA researchers. The findings suggest that exercise may temporarily make it easier for the brain to create new memories.


http://ift.tt/2CCWdjt

Researchers explore how people with Alzheimer's disease use end-of-life medical services

Researchers explore how people with Alzheimer's disease use end-of-life medical services:

Dementia Big
Because people are now living longer and often healthier lives, the rate of some illnesses that are more likely to develop with age has risen. These illnesses include dementia. In fact, the number of us living with dementia was already 47 million worldwide in 2015. It could reach 131 million by 2050.


http://ift.tt/2HCoI4E

Liquefied brain tissue after stroke may harm surviving brain, UA study finds

Liquefied brain tissue after stroke may harm surviving brain, UA study finds:

Dementia Big
Scientists have known for years that the brain liquefies after a stroke. If cut off from blood and oxygen for a long enough period, a portion of the brain will die, slowly morphing from a hard, rubbery substance into liquid goop.


http://ift.tt/2CCWa7h

End-of-life hospital and healthcare use among older adults with Alzheimer's disease

End-of-life hospital and healthcare use among older adults with Alzheimer's disease:

Dementia Big
Because people are now living longer and often healthier lives, the rate of some illnesses that are more likely to develop with age has risen. These illnesses include dementia. In fact, the number of us living with dementia was already 47 million worldwide in 2015. It could reach 131 million by 2050.


http://ift.tt/2HC2Mqc

Wednesday, February 21, 2018

Study reveals a significant link between heavy alcohol use and dementia

Study reveals a significant link between heavy alcohol use and dementia:

Dementia Big
New research has found alcohol use disorders to be one of the most vital avoidable risk factors for the onset of all types of dementia, early-onset dementia in particular.


http://ift.tt/2ogea32

Creative couples' intervention significantly helps people with Alzheimer's communicate

Creative couples' intervention significantly helps people with Alzheimer's communicate:

Dementia Big
They do it with the best of intentions. “Do you remember our wedding day?” “Who is that person next to you in the picture?” For couples with decades of shared memories, a partner’s decline in the ability to communicate is one of the most frightening and frustrating consequences of Alzheimer’s disease and related dementias. For these couples, the communication strategies they have used before simply do not work anymore. Impaired communication leads to misunderstandings, conflict, isolation, and loss of intimacy.


http://ift.tt/2EJjUZf

Largest study of its kind finds alcohol use biggest risk factor for dementia

Largest study of its kind finds alcohol use biggest risk factor for dementia:

Dementia Big
Alcohol use disorders are the most important preventable risk factors for the onset of all types of dementia, especially early-onset dementia. This according to a nationwide observational study, published in The Lancet Public Health journal, of over one million adults diagnosed with dementia in France.


http://ift.tt/2ojUw6f

Study reveals a significant link between heavy alcohol use and dementia

New research has found alcohol use disorders to be one of the most vital avoidable risk factors for the onset of all types of dementia, early-onset dementia in particular.

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http://ift.tt/2EJjSk5

Creative couples' intervention significantly helps people with Alzheimer's communicate

They do it with the best of intentions. “Do you remember our wedding day?” “Who is that person next to you in the picture?” For couples with decades of shared memories, a partner’s decline in the ability to communicate is one of the most frightening and frustrating consequences of Alzheimer’s disease and related dementias. For these couples, the communication strategies they have used before simply do not work anymore. Impaired communication leads to misunderstandings, conflict, isolation, and loss of intimacy.

from Dementia Big http://ift.tt/2sHjnWd via alcoholic dementia


http://ift.tt/2oglmvX

Largest study of its kind finds alcohol use biggest risk factor for dementia

Alcohol use disorders are the most important preventable risk factors for the onset of all types of dementia, especially early-onset dementia. This according to a nationwide observational study, published in The Lancet Public Health journal, of over one million adults diagnosed with dementia in France.

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http://ift.tt/2Fkrbjq

Study links heavy drinking with increased risk of dementia - Alzheimer's Society comment 

Study links heavy drinking with increased risk of dementia - Alzheimer's Society comment :

Dementia Big
A study published on 20 February in the Lancet Public Health has suggested that alcohol abuse addiction disorders are a major risk factor for dementia, specifically early onset dementia. 


http://ift.tt/2oncAf0

Study links heavy drinking with increased risk of dementia - Alzheimer's Society comment 

A study published on 20 February in the Lancet Public Health has suggested that alcohol abuse addiction disorders are a major risk factor for dementia, specifically early onset dementia. 



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Tuesday, February 20, 2018

The new Dementia Action Plan for Wales – Alzheimer’s Society comment

The new Dementia Action Plan for Wales – Alzheimer’s Society comment:

Dementia Big
On 14 February 2018, Welsh Government launched its brand new Dementia Action Plan for Wales.


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The new Dementia Action Plan for Wales – Alzheimer’s Society comment

On 14 February 2018, Welsh Government launched its brand new Dementia Action Plan for Wales.



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Data detectives shift suspicions in Alzheimer's to inside villain

Data detectives shift suspicions in Alzheimer's to inside villain:

Dementia Big
The mass pursuit of a conspicuous suspect in Alzheimer’s disease may have encumbered research success for decades. Now, a new data analysis that has untangled evidence amassed in years of Alzheimer’s studies encourages researchers to refocus their investigations.


http://ift.tt/2BCjEg1

New e-Health solution developed to prevent cardiovascular disease, dementia in senior citizens

New e-Health solution developed to prevent cardiovascular disease, dementia in senior citizens:

Dementia Big
An innovative e-Health solution, based on an interactive Internet platform, has been developed to support senior citizens in improving their lifestyle to prevent cardiovascular disease, cognitive decline and dementia.


http://ift.tt/2C8cSzG

Data detectives shift suspicions in Alzheimer's to inside villain

The mass pursuit of a conspicuous suspect in Alzheimer’s disease may have encumbered research success for decades. Now, a new data analysis that has untangled evidence amassed in years of Alzheimer’s studies encourages researchers to refocus their investigations.

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http://ift.tt/2EGIOgf

New e-Health solution developed to prevent cardiovascular disease, dementia in senior citizens

An innovative e-Health solution, based on an interactive Internet platform, has been developed to support senior citizens in improving their lifestyle to prevent cardiovascular disease, cognitive decline and dementia.

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http://ift.tt/2BDscDs

Monday, February 19, 2018

Emergency nurses experience regular verbal and physical abuse

The first ever review of the experience of hospital A&E staff reveals that they have resigned themselves to patient violence and aggression.

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http://ift.tt/2obkSaw

Emergency nurses experience regular verbal and physical abuse

Emergency nurses experience regular verbal and physical abuse:

Dementia Big
The first ever review of the experience of hospital A&E staff reveals that they have resigned themselves to patient violence and aggression.


http://ift.tt/2FgwznN

Friday, February 16, 2018

Molecular markers may ID Alzheimer's before clinical onset

(HealthDay)—For young adults with autosomal dominant Alzheimer’s disease (AD), molecular markers can identify changes associated with the disease before clinical onset, according to a study published online Feb. 12 in JAMA Neurology.

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Thursday, February 15, 2018

Not being aware of memory problems predicts onset of Alzheimer's disease

Not being aware of memory problems predicts onset of Alzheimer's disease:

Dementia Big
Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition worsen in a short time frame, a suspicion that now has been confirmed by a team of McGill University clinician scientists.


http://ift.tt/2F5wPG5

Genetic technique reverses Alzheimer's processes in mice

Genetic technique reverses Alzheimer's processes in mice:

Dementia Big
Researchers in the US have used genetic techniques to slow the progression of Alzheimer’s in mice that show features of the disease. The study, which centered around a protein called BACE1, was reported today in the Journal of Experimental Medicine.


http://ift.tt/2EreZfr

Poor fitness levels increase the risk dementia, concludes study

Poor fitness levels increase the risk dementia, concludes study:

Dementia Big
A new study has added to the growing body of evidence that regular exercise improves brain health and reduces the risk of Alzheimer’s disease.


http://ift.tt/2F7zmze

Amyloid protein may be transmitted through neurosurgical instruments, study suggests

Amyloid protein may be transmitted through neurosurgical instruments, study suggests:

Dementia Big
Amyloid beta pathology - protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study.


http://ift.tt/2Eut3Fb

Not being aware of memory problems predicts onset of Alzheimer's disease

Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition worsen in a short time frame, a suspicion that now has been confirmed by a team of McGill University clinician scientists.

from Dementia Big http://ift.tt/2HkbQ2G via alcoholic dementia


http://ift.tt/2F4BbNu

Genetic technique reverses Alzheimer's processes in mice

Researchers in the US have used genetic techniques to slow the progression of Alzheimer’s in mice that show features of the disease. The study, which centered around a protein called BACE1, was reported today in the Journal of Experimental Medicine.

from Dementia Big http://ift.tt/2Bxjd6P via alcoholic dementia


http://ift.tt/2EseCkQ

Poor fitness levels increase the risk dementia, concludes study

A new study has added to the growing body of evidence that regular exercise improves brain health and reduces the risk of Alzheimer’s disease.

from Dementia Big http://ift.tt/2C4vQHo via alcoholic dementia


http://ift.tt/2Eut0ct

Amyloid protein may be transmitted through neurosurgical instruments, study suggests

Amyloid beta pathology - protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study.

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http://ift.tt/2F6B8kv

Wednesday, February 14, 2018

Poor fitness linked to weaker brain fiber, higher dementia risk

Poor fitness linked to weaker brain fiber, higher dementia risk:

Dementia Big
Scientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer’s disease.


http://ift.tt/2Bvm0gD

Higher levels of lifestyle physical activity linked to more gray matter in older adults’ brains

Higher levels of lifestyle physical activity linked to more gray matter in older adults’ brains:

Dementia Big
Higher levels of lifestyle physical activity – such as house cleaning, walking a dog and gardening, as well as exercise – are associated with more gray matter in the brains of older adults, according to a study by researchers at Rush University Medical Center.


http://ift.tt/2C0S9h5

Researchers successfully reverse Alzheimer's disease in mouse model

Researchers successfully reverse Alzheimer's disease in mouse model:

Dementia Big
A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, thereby improving the animals’ cognitive function. The study, which will be published February 14 in the Journal of Experimental Medicine, raises hopes that drugs targeting this enzyme will be able to successfully treat Alzheimer’s disease in humans.


http://ift.tt/2BsNXWe

Poor fitness linked to weaker brain fiber, higher dementia risk

Scientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer’s disease.

from Dementia Big http://ift.tt/2F51l2S via alcoholic dementia


http://ift.tt/2EJESuq

Higher levels of lifestyle physical activity linked to more gray matter in older adults’ brains

Higher levels of lifestyle physical activity – such as house cleaning, walking a dog and gardening, as well as exercise – are associated with more gray matter in the brains of older adults, according to a study by researchers at Rush University Medical Center.

from Dementia Big http://ift.tt/2Ga7aez via alcoholic dementia


http://ift.tt/2sylWd2

Researchers successfully reverse Alzheimer's disease in mouse model

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, thereby improving the animals’ cognitive function. The study, which will be published February 14 in the Journal of Experimental Medicine, raises hopes that drugs targeting this enzyme will be able to successfully treat Alzheimer’s disease in humans.

from Dementia Big http://ift.tt/2EqdvWI via alcoholic dementia


http://ift.tt/2C1UxUI

Tuesday, February 13, 2018

Can treatments for arthritis be repurposed for dementia? – Alzheimer’s Society comments

Can treatments for arthritis be repurposed for dementia? – Alzheimer’s Society comments:

Dementia Big
New research suggests that drugs used to treat rheumatoid arthritis could reduce the risk of patients developing dementia.


http://ift.tt/2BqmK6y

Can treatments for arthritis be repurposed for dementia? – Alzheimer’s Society comments

New research suggests that drugs used to treat rheumatoid arthritis could reduce the risk of patients developing dementia.



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Arthritis drugs linked to lower Alzheimer's risk

Arthritis drugs linked to lower Alzheimer's risk:

Dementia Big
Scientists from the University of Southampton have teamed up with researchers from the University of Oxford to look at whether existing drugs for arthritis have any effect on a person’s risk of developing dementia. By looking at two groups of people – one receiving the drug treatment and one not – they found that fewer people developed dementia after five years of taking the drugs, compared to those who did not receive the treatment for arthritis.


http://ift.tt/2EDzhFT

How to support someone with dementia—and feel better yourself

How to support someone with dementia—and feel better yourself:

Dementia Big
Visiting a loved one with dementia can feel frustrating, even hopeless, but there are ways to turn that precious time into a better experience, says a University of Alberta researcher.


http://ift.tt/2ssJjou

Arthritis drugs linked to lower Alzheimer's risk

Scientists from the University of Southampton have teamed up with researchers from the University of Oxford to look at whether existing drugs for arthritis have any effect on a person’s risk of developing dementia. By looking at two groups of people – one receiving the drug treatment and one not – they found that fewer people developed dementia after five years of taking the drugs, compared to those who did not receive the treatment for arthritis.

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http://ift.tt/2EGnyq7

How to support someone with dementia—and feel better yourself

Visiting a loved one with dementia can feel frustrating, even hopeless, but there are ways to turn that precious time into a better experience, says a University of Alberta researcher.

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Monday, February 12, 2018

Scientists develop new array to identify biomarkers for wide range of diseases

Scientists develop new array to identify biomarkers for wide range of diseases:

Dementia Big
Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.


http://ift.tt/2Cg2iSO

People who survive childhood heart defects may be at elevated risk of developing dementia

People who survive childhood heart defects may be at elevated risk of developing dementia:

Dementia Big
People born with heart defects who survive into adulthood may be at higher risk of developing dementia, particularly dementia that starts before 65 years of age, according to new research in the American Heart Association’s journal Circulation.


http://ift.tt/2En8lLe

Survivors of childhood heart defects may have higher risk of premature dementia

Survivors of childhood heart defects may have higher risk of premature dementia:

Dementia Big
People born with heart defects who survive into adulthood may be at higher risk of developing dementia, particularly dementia that starts before 65 years of age, according to new research in the American Heart Association’s journal Circulation.


http://ift.tt/2CgSfga

Scientists develop new array to identify biomarkers for wide range of diseases

Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.

from Dementia Big http://ift.tt/2BpnQzA via alcoholic dementia


http://ift.tt/2EDVJyD

People who survive childhood heart defects may be at elevated risk of developing dementia

People born with heart defects who survive into adulthood may be at higher risk of developing dementia, particularly dementia that starts before 65 years of age, according to new research in the American Heart Association’s journal Circulation.

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http://ift.tt/2EDVGTt

Survivors of childhood heart defects may have higher risk of premature dementia

People born with heart defects who survive into adulthood may be at higher risk of developing dementia, particularly dementia that starts before 65 years of age, according to new research in the American Heart Association’s journal Circulation.

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Sunday, February 11, 2018

Alzheimer’s study on mice reveals important mechanism behind neural hyperactivity

Alzheimer´s disease is the key cause of dementia in elderly patients. Those affected develop deficiencies in their abilities to learn, think logically, communicate, and to master the challenges of everyday life.

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http://ift.tt/2BRTiYb

Friday, February 9, 2018

Scientists adapt new brain disease test for Parkinson's, dementia with Lewy bodies

Scientists adapt new brain disease test for Parkinson's, dementia with Lewy bodies:

Dementia Big
National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies. The group, led by NIH’s National Institute of Allergy and Infectious Diseases (NIAID), tested 60 cerebral spinal fluid samples, including 12 from people with Parkinson’s disease, 17 from people with dementia with Lewy bodies, and 31 controls, including 16 of whom had Alzheimer’s disease. The test correctly excluded all the 31 controls and diagnosed both Parkinson’s disease and dementia with Lewy bodies with 93 percent accuracy.


http://ift.tt/2EvwjTF

NIH scientists modify new RT-QuIC assay to detect Parkinson's, dementia with Lewy bodies

NIH scientists modify new RT-QuIC assay to detect Parkinson's, dementia with Lewy bodies:

Dementia Big
National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies.


http://ift.tt/2smnwyI

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity:

Dementia Big
Alzheimer´s disease is the key cause of dementia in elderly patients. Those affected develop deficiencies in their abilities to learn, think logically, communicate, and to master the challenges of everyday life. To find out more about how the disease comes about, researchers at the University of Tübingen used mice, developing the same amyloid protein deposits in their brains as human patients, and which also suffer memory loss. Several years ago, a team led by Professor Olga Garaschuk showed that in these mice, the disease coincided with a noticeable increase in nerve cell activity in the brain. There were similar findings in human Alzheimer’s patients.


http://ift.tt/2smnvuE

NIH scientists modify new RT-QuIC assay to detect Parkinson's, dementia with Lewy bodies

National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies.

from Dementia Big http://ift.tt/2BiJm9c via alcoholic dementia


http://ift.tt/2EtTv4V

Scientists adapt new brain disease test for Parkinson's, dementia with Lewy bodies

National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies. The group, led by NIH’s National Institute of Allergy and Infectious Diseases (NIAID), tested 60 cerebral spinal fluid samples, including 12 from people with Parkinson’s disease, 17 from people with dementia with Lewy bodies, and 31 controls, including 16 of whom had Alzheimer’s disease. The test correctly excluded all the 31 controls and diagnosed both Parkinson’s disease and dementia with Lewy bodies with 93 percent accuracy.

from Dementia Big http://ift.tt/2EfJ1Tv via alcoholic dementia


http://ift.tt/2smnuqA

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

Alzheimer´s disease is the key cause of dementia in elderly patients. Those affected develop deficiencies in their abilities to learn, think logically, communicate, and to master the challenges of everyday life. To find out more about how the disease comes about, researchers at the University of Tübingen used mice, developing the same amyloid protein deposits in their brains as human patients, and which also suffer memory loss. Several years ago, a team led by Professor Olga Garaschuk showed that in these mice, the disease coincided with a noticeable increase in nerve cell activity in the brain. There were similar findings in human Alzheimer’s patients.

from Dementia Big http://ift.tt/2Efxl37 via alcoholic dementia


http://ift.tt/2nSb05a

Thursday, February 8, 2018

Scientists identify potential early biomarker for Alzheimer's disease

One of the first clear signs of the onset of Alzheimer’s disease is the loss of short-term memory, the ability to remember recent events. However, scientists believe that changes in the brain begin decades before clinicians notice such signs. 

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http://ift.tt/2GYwpll

Changing the way we look at dementia

In November, six people with Alzheimer’s disease and related types of cognitive impairment stood before an audience of 100 in North Haven, Conn.

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http://ift.tt/2FWvGzG

Positivity keeps dementia at bay finds study

Persons who have developed positive attitudes towards life and aging are less likely to develop dementia finds a new study. Becca Levy from the Yale School of Public Health, USA, and colleagues have published the reports of this encouraging study in the latest issue of the journal PLOS ONE.

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http://ift.tt/2GWCFKi

Alzheimer's disease: Dual mechanism of actions of overactive and cytosolic BRCA1 in neuronal death

A new study suggests a dual mechanism of actions of overactive and cytosolic re-localized BRCA1, the major guardian of genomic stability, in neurons death by aberrant DNA damage response and presenilin 1 dysfunction in Alzheimer’s disease.

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http://ift.tt/2FWoFPs

Scientists identify potential early biomarker for Alzheimer's disease

Scientists identify potential early biomarker for Alzheimer's disease:

Dementia Big
One of the first clear signs of the onset of Alzheimer’s disease is the loss of short-term memory, the ability to remember recent events. However, scientists believe that changes in the brain begin decades before clinicians notice such signs. 


http://ift.tt/2Bgo5ga

Changing the way we look at dementia

Changing the way we look at dementia:

Dementia Big
In November, six people with Alzheimer’s disease and related types of cognitive impairment stood before an audience of 100 in North Haven, Conn.


http://ift.tt/2EqKqtA

Positivity keeps dementia at bay finds study

Positivity keeps dementia at bay finds study:

Dementia Big
Persons who have developed positive attitudes towards life and aging are less likely to develop dementia finds a new study. Becca Levy from the Yale School of Public Health, USA, and colleagues have published the reports of this encouraging study in the latest issue of the journal PLOS ONE.


http://ift.tt/2BjAz73

Alzheimer's disease: Dual mechanism of actions of overactive and cytosolic BRCA1 in neuronal death

Alzheimer's disease: Dual mechanism of actions of overactive and cytosolic BRCA1 in neuronal death:

Dementia Big
A new study suggests a dual mechanism of actions of overactive and cytosolic re-localized BRCA1, the major guardian of genomic stability, in neurons death by aberrant DNA damage response and presenilin 1 dysfunction in Alzheimer’s disease.


http://ift.tt/2EsUbHC

Wednesday, February 7, 2018

Positive attitudes about aging reduce risk of dementia in older adults

Positive attitudes about aging reduce risk of dementia in older adults:

Dementia Big
Research has shown that older persons who have acquired positive beliefs about old age from their surrounding culture are less likely to develop dementia. This protective effect was found for all participants, as well as among those carrying a gene that puts them at higher risk of developing dementia, a new study led by the Yale School of Public Health has found.


http://ift.tt/2GXby1V

Redefined Alzheimer's biology has implications for drug design

Redefined Alzheimer's biology has implications for drug design:

Dementia Big
Despite the 25-year focus on the build-up in brain tissues of one protein, amyloid beta, as the purported origin of Alzheimer’s disease (AD), a new study argues that it is likely triggered instead by the failure of a system that clears wastes from the brain - and actually begins decades before memories fade.


http://ift.tt/2FXbIoB

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia:

Dementia Big
Scientists have for the first time discovered a mechanism that limits the number of “cellular janitors” in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.


http://ift.tt/2GZdXsU

Social interaction could enhance dementia care, finds study

Social interaction could enhance dementia care, finds study:

Dementia Big
Increasing social interaction among people living with dementia in care homes could improve the quality of their life and save money, suggests new study.


http://ift.tt/2FXbHRz

One in five older adults experience brain network weakening following knee replacement surgery

One in five older adults experience brain network weakening following knee replacement surgery:

Dementia Big
A new University of Florida study finds that 23 percent of adults age 60 and older who underwent a total knee replacement experienced a decline in activity in at least one region of the brain responsible for specific cognitive functions. Fifteen percent of patients declined across all brain networks the team evaluated.


http://ift.tt/2GU2MSd

Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer's disease

Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer's disease:

Dementia Big
The supplement nicotinamide riboside (NR) – a form of vitamin B3 – prevented neurological damage and improved cognitive and physical function in a new mouse model of Alzheimer’s disease. The results of the study, conducted by researchers at the National Institute on Aging (NIA) part of the National Institutes of Health, suggest a potential new target for treating Alzheimer’s disease. The findings appear in the Feb. 5, 2018, issue of Proceedings of the National Academy of Sciences.


http://ift.tt/2FXbFZX

Loss of coenzyme Q10 increases pre-diabetes risk

Loss of coenzyme Q10 increases pre-diabetes risk:

Dementia Big
Levels of CoQ and the presence of insulin resistance were analyzed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.


http://ift.tt/2GWazih

Positive attitudes about aging reduce risk of dementia in older adults

Research has shown that older persons who have acquired positive beliefs about old age from their surrounding culture are less likely to develop dementia. This protective effect was found for all participants, as well as among those carrying a gene that puts them at higher risk of developing dementia, a new study led by the Yale School of Public Health has found.

from Dementia Big http://ift.tt/2BiavsY via alcoholic dementia


http://ift.tt/2E7eIhz

Redefined Alzheimer's biology has implications for drug design

Despite the 25-year focus on the build-up in brain tissues of one protein, amyloid beta, as the purported origin of Alzheimer’s disease (AD), a new study argues that it is likely triggered instead by the failure of a system that clears wastes from the brain - and actually begins decades before memories fade.

from Dementia Big http://ift.tt/2BK4lme via alcoholic dementia


http://ift.tt/2EPRfT2

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of “cellular janitors” in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

from Dementia Big http://ift.tt/2sfnDvZ via alcoholic dementia


http://ift.tt/2Ebhy54

Social interaction could enhance dementia care, finds study

Increasing social interaction among people living with dementia in care homes could improve the quality of their life and save money, suggests new study.

from Dementia Big http://ift.tt/2FUJScu via alcoholic dementia


http://ift.tt/2EP92dg

One in five older adults experience brain network weakening following knee replacement surgery

A new University of Florida study finds that 23 percent of adults age 60 and older who underwent a total knee replacement experienced a decline in activity in at least one region of the brain responsible for specific cognitive functions. Fifteen percent of patients declined across all brain networks the team evaluated.

from Dementia Big http://ift.tt/2ENdCJ2 via alcoholic dementia


http://ift.tt/2EaVyrj

Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer's disease

The supplement nicotinamide riboside (NR) – a form of vitamin B3 – prevented neurological damage and improved cognitive and physical function in a new mouse model of Alzheimer’s disease. The results of the study, conducted by researchers at the National Institute on Aging (NIA) part of the National Institutes of Health, suggest a potential new target for treating Alzheimer’s disease. The findings appear in the Feb. 5, 2018, issue of Proceedings of the National Academy of Sciences.

from Dementia Big http://ift.tt/2C1A2Dd via alcoholic dementia


http://ift.tt/2EOu7Ez

Loss of coenzyme Q10 increases pre-diabetes risk

Levels of CoQ and the presence of insulin resistance were analyzed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.

from Dementia Big http://ift.tt/2Ep8YTF via alcoholic dementia


http://ift.tt/2EblNxF

Sunday, February 4, 2018

Research highlights need for more structured educational programs for informal dementia carers

Research highlights need for more structured educational programs for informal dementia carers:

Dementia Big
Directly involving the thousands of family members and friends who serve as ‘informal carers’ for people with dementia in the evaluation of patients’ symptoms and behaviour could offer improved insights for healthcare professionals and help alleviate feelings of stress, guilt and isolation felt by many who fulfil these duties, a new study has found.


http://ift.tt/2DZMc5j

Research highlights need for more structured educational programs for informal dementia carers

Directly involving the thousands of family members and friends who serve as ‘informal carers’ for people with dementia in the evaluation of patients’ symptoms and behaviour could offer improved insights for healthcare professionals and help alleviate feelings of stress, guilt and isolation felt by many who fulfil these duties, a new study has found.

from Dementia Big http://ift.tt/2DZLl4B via alcoholic dementia


http://ift.tt/2GMZwYw

Saturday, February 3, 2018

Research highlights need for better support for thousands of informal dementia carers

Research highlights need for better support for thousands of informal dementia carers:

Dementia Big
Directly involving the thousands of family members and friends who serve as ‘informal carers’ for people with dementia in the evaluation of patients’ symptoms and behaviour could offer improved insights for healthcare professionals and help alleviate feelings of stress, guilt and isolation felt by many who fulfil these duties, a new study has found.


http://ift.tt/2DYyhZj

Blood-based marker for Alzheimer's disease shows diagnostic potential

Blood-based marker for Alzheimer's disease shows diagnostic potential:

Dementia Big
Researchers in Japan and Australia have used the ratio of different forms of the hallmark Alzheimer’s protein, amyloid, in blood to detect those who have high levels of the protein in their brain. Their findings are published today in the scientific publication Nature and take researchers a step closer to developing a blood test for the Alzheimer’s protein.


http://ift.tt/2EzBkbq

Blood-based marker for Alzheimer's disease shows diagnostic potential

Researchers in Japan and Australia have used the ratio of different forms of the hallmark Alzheimer’s protein, amyloid, in blood to detect those who have high levels of the protein in their brain. Their findings are published today in the scientific publication Nature and take researchers a step closer to developing a blood test for the Alzheimer’s protein.

from Dementia Big http://ift.tt/2BQiQ3o via alcoholic dementia


http://ift.tt/2DXNpX1

Research highlights need for better support for thousands of informal dementia carers

Directly involving the thousands of family members and friends who serve as ‘informal carers’ for people with dementia in the evaluation of patients’ symptoms and behaviour could offer improved insights for healthcare professionals and help alleviate feelings of stress, guilt and isolation felt by many who fulfil these duties, a new study has found.

from Dementia Big http://ift.tt/2DWJptN via alcoholic dementia


http://ift.tt/2ECyvXp

Friday, February 2, 2018

British Red Cross report highlights that older people at risk from emergency hospital readmissions

Alzheimer’s Society responds to In and Out of Hospital, a report published by the British Red Cross.



from Dementia Big http://ift.tt/2FGZTmq via alcoholic dementia
http://ift.tt/2s8PVID

British Red Cross report highlights that older people at risk from emergency hospital readmissions

British Red Cross report highlights that older people at risk from emergency hospital readmissions:

Dementia Big
Alzheimer’s Society responds to In and Out of Hospital, a report published by the British Red Cross.


http://ift.tt/2GE3X86

Low levels of alcohol helps the brain clear away toxins, study shows

Low levels of alcohol helps the brain clear away toxins, study shows:

Dementia Big
While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well.


http://ift.tt/2nCvE8x

Fight for Sight awards new grants for 13 vital eye research projects

Fight for Sight awards new grants for 13 vital eye research projects:

Dementia Big
Fight for Sight, the leading eye research charity, has awarded grants totaling over £180,000 for thirteen vital research projects in partnership with nine different organizations.


http://ift.tt/2DXjtOO

Low levels of alcohol helps the brain clear away toxins, study shows

While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well.

from Dementia Big http://ift.tt/2nEJiZ4 via alcoholic dementia


http://ift.tt/2DVwB70

Fight for Sight awards new grants for 13 vital eye research projects

Fight for Sight, the leading eye research charity, has awarded grants totaling over £180,000 for thirteen vital research projects in partnership with nine different organizations.

from Dementia Big http://ift.tt/2rXuQ3w via alcoholic dementia


http://ift.tt/2nzBB64

Thursday, February 1, 2018

Deep brain stimulation may be promising Alzheimer's treatment

(HealthDay)—For patients with Alzheimer’s disease (AD), the use of deep brain stimulation (DBS) at the ventral capsule/ventral striatum (VC/VS) region is well tolerated and is associated with less decline on the Clinical Dementia Rating-Sum of Boxes (CDR-SB), according to a study published online Jan. 30 in the Journal of Alzheimer’s Disease.

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http://ift.tt/2nzcFM4

Minimally invasive blood test for Alzheimer's disease

Scientists from Japan and Australia have teamed up to develop and validate a blood test for Alzheimer’s disease, with the potential to massively ramp up the pace of Alzheimer’s disease drug trials.

from Dementia Big http://ift.tt/2GCZVwO via alcoholic dementia


http://ift.tt/2DUqbVH

Deep brain stimulation may be promising Alzheimer's treatment

Deep brain stimulation may be promising Alzheimer's treatment:

Dementia Big
(HealthDay)—For patients with Alzheimer’s disease (AD), the use of deep brain stimulation (DBS) at the ventral capsule/ventral striatum (VC/VS) region is well tolerated and is associated with less decline on the Clinical Dementia Rating-Sum of Boxes (CDR-SB), according to a study published online Jan. 30 in the Journal of Alzheimer’s Disease.


http://ift.tt/2nyNnO6

Minimally invasive blood test for Alzheimer's disease

Minimally invasive blood test for Alzheimer's disease:

Dementia Big
Scientists from Japan and Australia have teamed up to develop and validate a blood test for Alzheimer’s disease, with the potential to massively ramp up the pace of Alzheimer’s disease drug trials.


http://ift.tt/2DSR5NQ

Wednesday, January 31, 2018

In-person license renewal tied to fewer crash hospitalizations of drivers with dementia

In-person license renewal tied to fewer crash hospitalizations of drivers with dementia:

Dementia Big
Requiring physicians to report patients with dementia to state driver’s licensing authorities is not associated with fewer hospitalizations from motor vehicle crashes. However, in-person license renewal laws and vision testing dramatically cut crashes involving drivers with dementia, according to a new study led by the University of Pittsburgh Graduate School of Public Health.


http://ift.tt/2DMiXPl

Inadequate oxygen levels during sleep increase risk of developing Alzheimer's disease

Inadequate oxygen levels during sleep increase risk of developing Alzheimer's disease:

Dementia Big
Inadequate oxygen levels during sleep can damage the brain and increase the risk of developing Alzheimer’s disease, University of Queensland researchers have found.


http://ift.tt/2EslQGh

Test lets volunteers check Alzheimer's risk, join clinical trials

Test lets volunteers check Alzheimer's risk, join clinical trials:

Dementia Big
People interested in helping test Alzheimer’s drugs can volunteer and get their cognitive abilities monitored on a new website run by Alzheimer’s researchers.


http://ift.tt/2DT7JsE

In-person license renewal tied to fewer crash hospitalizations of drivers with dementia

Requiring physicians to report patients with dementia to state driver’s licensing authorities is not associated with fewer hospitalizations from motor vehicle crashes. However, in-person license renewal laws and vision testing dramatically cut crashes involving drivers with dementia, according to a new study led by the University of Pittsburgh Graduate School of Public Health.

from Dementia Big http://ift.tt/2DSCJsM via alcoholic dementia


http://ift.tt/2Euw09w

Inadequate oxygen levels during sleep increase risk of developing Alzheimer's disease

Inadequate oxygen levels during sleep can damage the brain and increase the risk of developing Alzheimer’s disease, University of Queensland researchers have found.

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http://ift.tt/2DO2UAF

Test lets volunteers check Alzheimer's risk, join clinical trials

People interested in helping test Alzheimer’s drugs can volunteer and get their cognitive abilities monitored on a new website run by Alzheimer’s researchers.

from Dementia Big http://ift.tt/2rWFxTW via alcoholic dementia


http://ift.tt/2Etxoco

Tuesday, January 30, 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

The effects of Huntington’s disease can be seen as early as conception, finds new study:

Dementia Big
In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.


http://ift.tt/2nrEGoN

Neuroscientist wins NIH grant to find whether pear- or apple-shape physique is best for our brains

Neuroscientist wins NIH grant to find whether pear- or apple-shape physique is best for our brains:

Dementia Big
With the new year still ringing, many of us have fat on our minds, but Dr. Alexis M. Stranahan is more interested in what fat does to our minds.


http://ift.tt/2DNfHY1

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

from Dementia Big http://ift.tt/2EoAUVc via alcoholic dementia


http://ift.tt/2BDXhTN

Neuroscientist wins NIH grant to find whether pear- or apple-shape physique is best for our brains

With the new year still ringing, many of us have fat on our minds, but Dr. Alexis M. Stranahan is more interested in what fat does to our minds.

from Dementia Big http://ift.tt/2DNx4Ij via alcoholic dementia


http://ift.tt/2nnUwl6

Monday, January 29, 2018

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells:

Dementia Big
With new findings, scientists may be poised to break a long impasse in research on Huntington’s disease, a fatal hereditary disorder for which there is currently no treatment.


http://ift.tt/2rV74p5

Body clock disruptions occur years before memory loss in Alzheimer's

Body clock disruptions occur years before memory loss in Alzheimer's:

Dementia Big
People with Alzheimer’s disease are known to have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Now, new research at Washington University School of Medicine in St. Louis indicates that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer’s.


http://ift.tt/2GssSLD

Enhanced lifestyle counselling could protect against Alzheimer’s disease, finds new study

Enhanced lifestyle counselling could protect against Alzheimer’s disease, finds new study:

Dementia Big
Enhanced lifestyle counselling could prevent cognitive decline in people who are genetically predisposed to develop Alzheimer’s disease, finds new study.


http://ift.tt/2rOfFcT

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

With new findings, scientists may be poised to break a long impasse in research on Huntington’s disease, a fatal hereditary disorder for which there is currently no treatment.

from Dementia Big http://ift.tt/2rP9sNZ via alcoholic dementia


http://ift.tt/2DXWKkG

Body clock disruptions occur years before memory loss in Alzheimer's

People with Alzheimer’s disease are known to have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Now, new research at Washington University School of Medicine in St. Louis indicates that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer’s.

from Dementia Big http://ift.tt/2njnSRQ via alcoholic dementia


http://ift.tt/2FtuEe7

Enhanced lifestyle counselling could protect against Alzheimer’s disease, finds new study

Enhanced lifestyle counselling could prevent cognitive decline in people who are genetically predisposed to develop Alzheimer’s disease, finds new study.

from Dementia Big http://ift.tt/2Fr2a4M via alcoholic dementia


http://ift.tt/2DVzovZ

Saturday, January 27, 2018

Aerobic exercise may improve cognitive symptoms in older adults at risk for AD

Aerobic exercise may improve cognitive symptoms in older adults at risk for AD:

Dementia Big
Alzheimer’s disease (AD) is a brain disorder that destroys memory and thinking skills over time. It is the most common form of dementia in older adults.


http://ift.tt/2BxvynP

Aerobic exercise may improve cognitive symptoms in older adults at risk for AD

Alzheimer’s disease (AD) is a brain disorder that destroys memory and thinking skills over time. It is the most common form of dementia in older adults.

from Dementia Big http://ift.tt/2EfyFDF via alcoholic dementia


http://ift.tt/2BwI1YT

Friday, January 26, 2018

Aerobic exercise may mildly delay, slightly improve Alzheimer's symptoms

Aerobic exercise may mildly delay, slightly improve Alzheimer's symptoms:

Dementia Big
Alzheimer’s disease (AD) is a brain disorder that destroys memory and thinking skills over time. It is the most common form of dementia in older adults. There is presently no cure for the condition, though treatment options are available. Today, some 5.3 million Americans live with AD, and it is now the sixth leading cause of death in the United States. The number of older adults who will develop AD is expected to more than triple by 2050.


http://ift.tt/2DSE3z6

Diabetes protein linked to memory loss

Diabetes protein linked to memory loss:

Dementia Big
Researchers in China and the UK have found that the level of a protein, HbA1c, commonly used to assess if someone has diabetes is linked to worsening memory and thinking performance in healthy ageing adults. The findings are published today in the scientific journal Diabetologia.


http://ift.tt/2FiNTXK

Diabetes protein linked to memory loss

Researchers in China and the UK have found that the level of a protein, HbA1c, commonly used to assess if someone has diabetes is linked to worsening memory and thinking performance in healthy ageing adults. The findings are published today in the scientific journal Diabetologia.

from Dementia Big http://ift.tt/2naSFPM via alcoholic dementia


http://ift.tt/2DOqaSi

Aerobic exercise may mildly delay, slightly improve Alzheimer's symptoms

Alzheimer’s disease (AD) is a brain disorder that destroys memory and thinking skills over time. It is the most common form of dementia in older adults. There is presently no cure for the condition, though treatment options are available. Today, some 5.3 million Americans live with AD, and it is now the sixth leading cause of death in the United States. The number of older adults who will develop AD is expected to more than triple by 2050.

from Dementia Big http://ift.tt/2GjljHh via alcoholic dementia


http://ift.tt/2Fknnxv

Thursday, January 25, 2018

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals:

Dementia Big
Enhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer’s disease, according to a new study published in JAMA Neurology.


http://ift.tt/2Bu5Znv

Enhanced lifestyle counseling prevents cognitive decline even in genetically susceptible people

Enhanced lifestyle counseling prevents cognitive decline even in genetically susceptible people:

Dementia Big
Enhanced lifestyle counseling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer’s disease, according to a new study published in JAMA Neurology.


http://ift.tt/2GeRMhR

Alzheimer's drug targeting soluble amyloid falls short in a large clinical trial

Alzheimer's drug targeting soluble amyloid falls short in a large clinical trial:

Dementia Big
A paper published today in the New England Journal of Medicine reports that solanezumab, a monoclonal antibody-based treatment for Alzheimer’s disease developed by Eli Lilly that targets amyloid plaques, did not significantly slow cognitive decline.


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Drug may help those with dementia with Lewy bodies

Drug may help those with dementia with Lewy bodies:

Dementia Big
New help may be on the way for people with dementia with Lewy bodies, which is the second most common neurodegenerative type of dementia after Alzheimer’s disease. The disease can cause movement problems and issues such as hallucinations in addition to thinking and memory problems. But the drug used to treat the movement problems can also exacerbate the hallucinations, delusions and other psychiatric problems.


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Enhanced lifestyle counseling prevents cognitive decline even in genetically susceptible people

Enhanced lifestyle counseling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer’s disease, according to a new study published in JAMA Neurology.

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Drug may help those with dementia with Lewy bodies

New help may be on the way for people with dementia with Lewy bodies, which is the second most common neurodegenerative type of dementia after Alzheimer’s disease. The disease can cause movement problems and issues such as hallucinations in addition to thinking and memory problems. But the drug used to treat the movement problems can also exacerbate the hallucinations, delusions and other psychiatric problems.

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Alzheimer's drug targeting soluble amyloid falls short in a large clinical trial

A paper published today in the New England Journal of Medicine reports that solanezumab, a monoclonal antibody-based treatment for Alzheimer’s disease developed by Eli Lilly that targets amyloid plaques, did not significantly slow cognitive decline.

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Wednesday, January 24, 2018

Number of older people with multi-morbidity likely to expand over next 20 years, study finds

Number of older people with multi-morbidity likely to expand over next 20 years, study finds:

Dementia Big
A study published today in Age and Ageing, the scientific journal of the British Geriatrics Society, reports that the number of older people diagnosed with four or more diseases will double between 2015 and 2035. A third of these people will be diagnosed with dementia, depression or a cognitive impairment.


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Number of older people with multi-morbidity likely to expand over next 20 years, study finds

A study published today in Age and Ageing, the scientific journal of the British Geriatrics Society, reports that the number of older people diagnosed with four or more diseases will double between 2015 and 2035. A third of these people will be diagnosed with dementia, depression or a cognitive impairment.

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Tuesday, January 23, 2018

Personality changes occur early on during development of Alzheimer's disease, research finds

Personality changes occur early on during development of Alzheimer's disease, research finds:

Dementia Big
A key feature of Alzheimer’s disease is memory loss and losing one’s ability to think and make decisions (also called “cognitive ability”). Those changes can begin slowly, during a phase called “mild cognitive impairment” (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer’s disease.


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Personality changes during transition to developing mild cognitive impairment

Personality changes during transition to developing mild cognitive impairment:

Dementia Big
A key feature of Alzheimer’s disease is memory loss and losing one’s ability to think and make decisions (also called “cognitive ability”). Those changes can begin slowly, during a phase called “mild cognitive impairment” (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer’s disease.


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Curcumin could provide meaningful cognitive benefits, study suggests

Curcumin could provide meaningful cognitive benefits, study suggests:

Dementia Big
Lovers of Indian food, give yourselves a second helping: Daily consumption of a certain form of curcumin – the substance that gives Indian curry its bright color – improved memory and mood in people with mild, age-related memory loss, according to the results of a study conducted by UCLA researchers.


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Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy:

Dementia Big
Alzheimer’s disease, a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure.


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Personality changes occur early on during development of Alzheimer's disease, research finds

A key feature of Alzheimer’s disease is memory loss and losing one’s ability to think and make decisions (also called “cognitive ability”). Those changes can begin slowly, during a phase called “mild cognitive impairment” (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer’s disease.

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Curcumin could provide meaningful cognitive benefits, study suggests

Lovers of Indian food, give yourselves a second helping: Daily consumption of a certain form of curcumin – the substance that gives Indian curry its bright color – improved memory and mood in people with mild, age-related memory loss, according to the results of a study conducted by UCLA researchers.

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Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

Alzheimer’s disease, a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure.

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Personality changes during transition to developing mild cognitive impairment

A key feature of Alzheimer’s disease is memory loss and losing one’s ability to think and make decisions (also called “cognitive ability”). Those changes can begin slowly, during a phase called “mild cognitive impairment” (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer’s disease.

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Sunday, January 21, 2018

Researchers describe atom-by-atom changes in ALS-linked protein

Researchers describe atom-by-atom changes in ALS-linked protein:

Dementia Big
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.


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Researchers describe atom-by-atom changes in ALS-linked protein

For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.

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Friday, January 19, 2018

New initiative seeks to transform the way people live with dementia

New initiative seeks to transform the way people live with dementia:

Dementia Big
Challenge Dementia, supported by Nesta, launches today as the first national search for next generation products, technologies and services that could transform the way people live with dementia helping them to live enjoyable and fulfilling lives for as long as possible.


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Rocky start for Alzheimer's drug research in 2018

Rocky start for Alzheimer's drug research in 2018:

Dementia Big
The year 2018, barely underway, has already dealt a series of disheartening blows to the quest for an Alzheimer’s cure.


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New initiative seeks to transform the way people live with dementia

Challenge Dementia, supported by Nesta, launches today as the first national search for next generation products, technologies and services that could transform the way people live with dementia helping them to live enjoyable and fulfilling lives for as long as possible.

from Dementia Big http://ift.tt/2FUlaK2 via alcoholic dementia


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Rocky start for Alzheimer's drug research in 2018

The year 2018, barely underway, has already dealt a series of disheartening blows to the quest for an Alzheimer’s cure.

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Thursday, January 18, 2018

Signaling molecules likely involved in concussions, rodent studies show

Signaling molecules likely involved in concussions, rodent studies show:

Dementia Big
Traumatic brain injuries, whether suffered from a blow on the football field or the battle field, can be devastating, leading to disability and shortened lives.


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Neuronal loss very limited in Alzheimer's disease, new study shows

Neuronal loss very limited in Alzheimer's disease, new study shows:

Dementia Big
Frequently encountered in the elderly, Alzheimer’s is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endings, or synapses. A joint French and Canadian study published in Scientific Reports now challenges this view.


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