Daytime sleepiness is very common in the elderly with prevalence rates of up to 50 percent. Caused by sleep-disordered breathing, a disruption of normal breathing during sleep, these cause recurrent awakenings and subsequent excessive daytime sleepiness.
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Daytime sleepiness is very common in the elderly with prevalence rates of up to 50 percent. Caused by sleep-disordered breathing, a disruption of normal breathing during sleep, these cause recurrent awakenings and subsequent excessive daytime sleepiness.
One of the earliest signs of Alzheimer’s disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment – before symptoms of memory problems begin to surface.
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Tiny air pollution particles – the type that mainly comes from power plants and automobiles – may greatly increase the chance of dementia, including Alzheimer’s disease, according to USC-led research.
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Tiny air pollution particles—the type that mainly comes from power plants and automobiles—may greatly increase the chance of dementia, including Alzheimer’s disease, according to USC-led research.
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One of the earliest signs of Alzheimer’s disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment—before symptoms of memory problems begin to surface. Whether it is a cause or consequence of neurological dysfunction has been unclear, but new research at the Lewis Katz School of Medicine at Temple University now shows unequivocally that glucose deprivation in the brain triggers the onset of cognitive decline, memory impairment in particular.
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A new study, published on the cover of the scientific journal Biological Psychiatry and lead by Dr Carlos Saura from the Institut de Neurociències at the Universitat Autònoma de Barcelona, reveals a new molecular mechanism essential for associative memory encoding in the hippocampus.
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Dementia Big
One of the earliest signs of Alzheimer’s disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment – before symptoms of memory problems begin to surface.
Dementia Big
Tiny air pollution particles – the type that mainly comes from power plants and automobiles – may greatly increase the chance of dementia, including Alzheimer’s disease, according to USC-led research.
Dementia Big
Tiny air pollution particles—the type that mainly comes from power plants and automobiles—may greatly increase the chance of dementia, including Alzheimer’s disease, according to USC-led research.
Dementia Big
One of the earliest signs of Alzheimer’s disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment—before symptoms of memory problems begin to surface. Whether it is a cause or consequence of neurological dysfunction has been unclear, but new research at the Lewis Katz School of Medicine at Temple University now shows unequivocally that glucose deprivation in the brain triggers the onset of cognitive decline, memory impairment in particular.
Dementia Big
A new study, published on the cover of the scientific journal Biological Psychiatry and lead by Dr Carlos Saura from the Institut de Neurociències at the Universitat Autònoma de Barcelona, reveals a new molecular mechanism essential for associative memory encoding in the hippocampus.
Dementia Big
Mayo Clinic researchers have found that engaging in mentally stimulating activities, even late in life, may protect against new-onset mild cognitive impairment, which is the intermediate stage between normal cognitive aging and dementia.
Dementia Big
People who speak two or more languages appear to weather the ravages of Alzheimer’s disease better than people who have only mastered one language, a new Italian study suggests.
Mayo Clinic researchers have found that engaging in mentally stimulating activities, even late in life, may protect against new-onset mild cognitive impairment, which is the intermediate stage between normal cognitive aging and dementia.
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People who speak two or more languages appear to weather the ravages of Alzheimer’s disease better than people who have only mastered one language, a new Italian study suggests.
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Dementia Big
Research published in the current issue of the Journal of Parasitology suggests a potential link between a common parasite and Alzheimer’s disease.
Research published in the current issue of the Journal of Parasitology suggests a potential link between a common parasite and Alzheimer’s disease.
Cerebral small vessel disease (SVD) is thought to contribute to Alzheimer’s disease (AD) through abnormalities in white matter networks. Gray matter (GM) hub covariance networks share only partial overlap with white matter connectivity, and their relationship with SVD has not been examined in AD.
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Dementia Big
Cerebral small vessel disease (SVD) is thought to contribute to Alzheimer’s disease (AD) through abnormalities in white matter networks. Gray matter (GM) hub covariance networks share only partial overlap with white matter connectivity, and their relationship with SVD has not been examined in AD.
Dementia Big
A large-scale, population based study led by Dr. Laurent Azoulay, Senior Investigator with the Lady Davis Institute at the Jewish General Hospital, has concluded that the use of androgen deprivation therapy (ADT) to treat advanced prostate cancer is not associated with an increased risk of Alzheimer disease.
Dementia Big
Important steps in planning tumor surgery include identifying borders between tumor and healthy tissue and assessing the tumor stiffness, e.g. hard and calcified or soft and pliant.
Dementia Big
Biochemical reactions that cause Alzheimer’s disease could begin in the womb or just after birth if the fetus or newborn does not get enough vitamin A, according to new research from the University of British Columbia.
A large-scale, population based study led by Dr. Laurent Azoulay, Senior Investigator with the Lady Davis Institute at the Jewish General Hospital, has concluded that the use of androgen deprivation therapy (ADT) to treat advanced prostate cancer is not associated with an increased risk of Alzheimer disease.
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Biochemical reactions that cause Alzheimer’s disease could begin in the womb or just after birth if the fetus or newborn does not get enough vitamin A, according to new research from the University of British Columbia.
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Important steps in planning tumor surgery include identifying borders between tumor and healthy tissue and assessing the tumor stiffness, e.g. hard and calcified or soft and pliant.
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Dementia Big
(HealthDay)—Parking yourself in front of the TV may make you as likely to develop dementia as people genetically predisposed to the condition, a Canadian study suggests.
Dementia Big
Biochemical reactions that cause Alzheimer’s disease could begin in the womb or just after birth if the fetus or newborn does not get enough vitamin A, according to new research from the University of British Columbia.
Biochemical reactions that cause Alzheimer’s disease could begin in the womb or just after birth if the fetus or newborn does not get enough vitamin A, according to new research from the University of British Columbia.
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(HealthDay)—Parking yourself in front of the TV may make you as likely to develop dementia as people genetically predisposed to the condition, a Canadian study suggests.
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Dementia Big
Acetylcholine is a neurotransmitter in the brain that plays an important role in controlling attention and cognition. Acetylcholine system dysfunction is believed to be one of the causes of Alzheimer’s disease (AD) and vascular dementia.
Acetylcholine is a neurotransmitter in the brain that plays an important role in controlling attention and cognition. Acetylcholine system dysfunction is believed to be one of the causes of Alzheimer’s disease (AD) and vascular dementia.
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Dementia Big
Former Prime Minister, David Cameron, has today (Wednesday 25 January) been announced as the new President of Alzheimer’s Research UK.
Dementia Big
The leading dementia charity has launched its new brand to give a stronger voice to every single person affected by dementia.
Dementia Big
Healthcare market intelligence provider, LaingBuisson, has today revealed that the average fee per resident paid to care homes falls short of the real cost of service - by more than £100 a week.
Dementia Big
A dream will come true for ‘Songaminute Man’ Teddy Mac with the release of his first ever single, which will raise funds for Alzheimer’s Society.
Former Prime Minister, David Cameron, has today (Wednesday 25 January) been announced as the new President of Alzheimer’s Research UK.
The leading dementia charity has launched its new brand to give a stronger voice to every single person affected by dementia.
Healthcare market intelligence provider, LaingBuisson, has today revealed that the average fee per resident paid to care homes falls short of the real cost of service - by more than £100 a week.
A dream will come true for ‘Songaminute Man’ Teddy Mac with the release of his first ever single, which will raise funds for Alzheimer’s Society.
Dementia Big
Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.
Dementia Big
Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury.
Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.
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Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury.
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Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells. Such tangles are a hallmark of Alzheimer’s and other neurodegenerative diseases.
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We have just finished reading the paradigm-setting study by the Workgroup on Calcium Hypothesis convened by the Alzheimer’s Association and the journal Alzheimer’s & Dementia [1].
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Dementia Big
Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells. Such tangles are a hallmark of Alzheimer’s and other neurodegenerative diseases.
Dementia Big
We have just finished reading the paradigm-setting study by the Workgroup on Calcium Hypothesis convened by the Alzheimer’s Association and the journal Alzheimer’s & Dementia [1].
Dementia Big
Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury.
Dementia Big
The UK’s current health and social care system isn’t fit for purpose when it comes to caring for people living with dementia (PLWD) who also have other illnesses and chronic conditions.
Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury.
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The UK’s current health and social care system isn’t fit for purpose when it comes to caring for people living with dementia (PLWD) who also have other illnesses and chronic conditions.
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Promising, early studies of deep brain stimulation (DBS) for the treatment of Alzheimer’s disease have paved a path for future clinical trials, but there are unique ethical challenges with this vulnerable population regarding decision making and post-study treatment access that need to be addressed as they ramp up, Penn Medicine researchers argue in a new review in the Journal of Alzheimer’s Disease.
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Certain edible and medicinal mushrooms contain bioactive compounds that may enhance nerve growth in the brain and protect against neurotoxic stimuli such as inflammation that contribute to neurodegenerative diseases like dementia and Alzheimer’s disease. The evidence supporting a potential role of mushrooms as functional foods to reduce or delay development of age-related neurodegeneration is presented in an article published in Journal of Medicinal Food.
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Dementia Big
Promising, early studies of deep brain stimulation (DBS) for the treatment of Alzheimer’s disease have paved a path for future clinical trials, but there are unique ethical challenges with this vulnerable population regarding decision making and post-study treatment access that need to be addressed as they ramp up, Penn Medicine researchers argue in a new review in the Journal of Alzheimer’s Disease.
Dementia Big
Certain edible and medicinal mushrooms contain bioactive compounds that may enhance nerve growth in the brain and protect against neurotoxic stimuli such as inflammation that contribute to neurodegenerative diseases like dementia and Alzheimer’s disease. The evidence supporting a potential role of mushrooms as functional foods to reduce or delay development of age-related neurodegeneration is presented in an article published in Journal of Medicinal Food.
It was when Xinglong Wang, PhD, received a call from a desperate father of a middle-aged son with amyotrophic lateral sclerosis (ALS) that he realized the extraordinary importance of his work. “Can you help save my son’s life?” the parent asked. On that day, Wang, assistant professor of pathology at Case Western Reserve University School of Medicine, felt the weight of human suffering on his shoulders. But this is a weight that Wang can bear. He may be in the process of entirely upending the current scientific view of ALS and other neuronal diseases. He may be a pioneer who forces scientists to discard years of medical dogma and leads clinicians to significantly improved treatments.
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Dementia Big
It was when Xinglong Wang, PhD, received a call from a desperate father of a middle-aged son with amyotrophic lateral sclerosis (ALS) that he realized the extraordinary importance of his work. “Can you help save my son’s life?” the parent asked. On that day, Wang, assistant professor of pathology at Case Western Reserve University School of Medicine, felt the weight of human suffering on his shoulders. But this is a weight that Wang can bear. He may be in the process of entirely upending the current scientific view of ALS and other neuronal diseases. He may be a pioneer who forces scientists to discard years of medical dogma and leads clinicians to significantly improved treatments.
Dementia Big
Cassidy Fiford, a native of Hayling Island and a PhD student at University College London, has celebrated after making a discovery showing that damage to blood vessels in the brain can drive shrinking of the hippocampus, an area of the brain critical for memory. Her findings are helping researchers shed more light on what drives damage in the brain in Alzheimer’s and how it can be stopped.
Dementia Big
In a recent study of adults with early memory loss, a West Virginia University research team lead by Dr. Kim Innes found that practice of a simple meditation or music listening program may have multiple benefits for older adults with preclinical memory loss.
Dementia Big
New research funded by Pharmacy Research UK published today, 20 January, reveals people with dementia may struggle with managing their medication – exposing them to side-effects, medication errors and an increased risk of non-adherence to drug treatment.
Cassidy Fiford, a native of Hayling Island and a PhD student at University College London, has celebrated after making a discovery showing that damage to blood vessels in the brain can drive shrinking of the hippocampus, an area of the brain critical for memory. Her findings are helping researchers shed more light on what drives damage in the brain in Alzheimer’s and how it can be stopped.
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In a recent study of adults with early memory loss, a West Virginia University research team lead by Dr. Kim Innes found that practice of a simple meditation or music listening program may have multiple benefits for older adults with preclinical memory loss.
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New research funded by Pharmacy Research UK published today, 20 January, reveals people with dementia may struggle with managing their medication – exposing them to side-effects, medication errors and an increased risk of non-adherence to drug treatment.
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Dementia Big
We thank Mapstone et al. for their comments on our failure to replicate their index findings on plasma metabolite biomarkers of incident Alzheimer disease (AD) [1]. They raise three main concerns with our study [2] which they suggest precludes comparison with their earlier report. We respond to each of these in the following sections:
We thank Mapstone et al. for their comments on our failure to replicate their index findings on plasma metabolite biomarkers of incident Alzheimer disease (AD) [1]. They raise three main concerns with our study [2] which they suggest precludes comparison with their earlier report. We respond to each of these in the following sections:
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Patients in Leicestershire experiencing mental health issues in later life are to benefit from an investment into cutting-edge psychiatry research at the University of Leicester by the Leicestershire Partnership NHS Trust.
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Dementia Big
Patients in Leicestershire experiencing mental health issues in later life are to benefit from an investment into cutting-edge psychiatry research at the University of Leicester by the Leicestershire Partnership NHS Trust.
Northwestern Medicine scientists showed for the first time that non-invasive brain stimulation can be used like a scalpel, rather than like a hammer, to cause a specific improvement in precise memory.
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Dementia Big
Northwestern Medicine scientists showed for the first time that non-invasive brain stimulation can be used like a scalpel, rather than like a hammer, to cause a specific improvement in precise memory.
Dementia Big
Columbia University Medical Center (CUMC) researchers have discovered that the spatial disorientation that leads to wandering in many Alzheimer’s disease patients is caused by the accumulation of tau protein in navigational nerve cells in the brain. The findings, in mice, could lead to early diagnostic tests for Alzheimer’s and highlight novel targets for treating this common and troubling symptom.
Columbia University Medical Center (CUMC) researchers have discovered that the spatial disorientation that leads to wandering in many Alzheimer’s disease patients is caused by the accumulation of tau protein in navigational nerve cells in the brain. The findings, in mice, could lead to early diagnostic tests for Alzheimer’s and highlight novel targets for treating this common and troubling symptom.
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Dementia Big
When hospitalised, people can become acutely confused and disorientated. This condition, known as delirium, affects a quarter of older patients and new research by UCL and the University of Cambridge shows it may have long-lasting consequences, including accelerating the dementia process.
When hospitalised, people can become acutely confused and disorientated. This condition, known as delirium, affects a quarter of older patients and new research by UCL and the University of Cambridge shows it may have long-lasting consequences, including accelerating the dementia process.
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Dementia Big
Researchers from the University of California and Cardiff University have made a breakthrough in the understanding of AIDS-related dementia, discovering the role of a neuron protein which was also found to affect learning abilities in healthy subjects.
Researchers from the University of California and Cardiff University have made a breakthrough in the understanding of AIDS-related dementia, discovering the role of a neuron protein which was also found to affect learning abilities in healthy subjects.
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New guidelines have been developed that it is hoped will help to progress research into vascular cognitive impairment (VCI) following a study led by academics at the University of Bristol that brought together the views of over 150 researchers in 27 countries.
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Last month, Vida Grange- a specialist dementia care home operated by Vida Healthcare - opened its doors to its first residents.
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New study results published online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association suggest that onset of high blood pressure later in life is associated with lower dementia risk after age 90, especially if hypertension is developed at age 80 or older.
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Dementia Big
New guidelines have been developed that it is hoped will help to progress research into vascular cognitive impairment (VCI) following a study led by academics at the University of Bristol that brought together the views of over 150 researchers in 27 countries.
Dementia Big
Last month, Vida Grange- a specialist dementia care home operated by Vida Healthcare - opened its doors to its first residents.
Dementia Big
New study results published online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association suggest that onset of high blood pressure later in life is associated with lower dementia risk after age 90, especially if hypertension is developed at age 80 or older.
A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease.
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New study results published online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association suggest that onset of high blood pressure later in life is associated with lower dementia risk after age 90, especially if hypertension is developed at age 80 or older.
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We investigated the association between age of onset of hypertension and dementia risk in an oldest-old cohort.
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Dementia Big
A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease.
Dementia Big
We investigated the association between age of onset of hypertension and dementia risk in an oldest-old cohort.
Dementia Big
New study results published online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association suggest that onset of high blood pressure later in life is associated with lower dementia risk after age 90, especially if hypertension is developed at age 80 or older.
Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy. Not only do individuals with cerebrovascular diseases have a much higher incidence of cortical microinfarcts (mini-strokes), but post-mortem histological and in vivo radiological studies also find that the burden of microinfarcts is significantly greater among people with vascular cognitive impairment and dementia (VCID) than in age-matched, non-demented individuals.
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Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.
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Dementia Big
Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy. Not only do individuals with cerebrovascular diseases have a much higher incidence of cortical microinfarcts (mini-strokes), but post-mortem histological and in vivo radiological studies also find that the burden of microinfarcts is significantly greater among people with vascular cognitive impairment and dementia (VCID) than in age-matched, non-demented individuals.
Dementia Big
Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.
Dementia Big
Nearly 20 percent of older Americans experience depression and the highest rate of suicide is among older adult Caucasian males.
Nearly 20 percent of older Americans experience depression and the highest rate of suicide is among older adult Caucasian males.
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New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which…
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Dementia Big
New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which…
Research carried out by Plymouth University into the experience of dementia in farming and farming families, and its impact on their businesses and home lives, has identified four areas of concern which need to be addressed if dementia in the countryside is to be managed.
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Dementia Big
Research carried out by Plymouth University into the experience of dementia in farming and farming families, and its impact on their businesses and home lives, has identified four areas of concern which need to be addressed if dementia in the countryside is to be managed.
Dementia Big
Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer’s disease (AD). The USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset of Alzheimer’s disease. This discovery by the LCSB researchers, led by Dr. Enrico Glaab, may open a new door to developing active ingredients to treat Alzheimer’s disease. The scientists recently published their findings in the journal Molecular Neurobiology.
Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer’s disease (AD). The USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset of Alzheimer’s disease. This discovery by the LCSB researchers, led by Dr. Enrico Glaab, may open a new door to developing active ingredients to treat Alzheimer’s disease. The scientists recently published their findings in the journal Molecular Neurobiology.
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Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland.
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Research carried out by Plymouth University into the experience of dementia in farming and farming families, and its impact on their businesses and home lives, has identified four areas of concern which need to be addressed if dementia in the countryside is to be managed. It is the first time that research has addressed this issue in farming.
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Rutgers University scientists have discovered a molecular pathway in the brain that may help provide answers to long-term memory problems in the elderly and aid researchers in identifying drug-based therapies to prevent dementia.
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New research published online in The FASEB Journal, suggests that carriers of the Apolipoprotein E4 allele, which is the single strongest genetic predictor of Alzheimer’s disease and is associated with cognitive decline and cardiovascular disease, may have a reduced risk of cognitive decline associated with parasitic diseases.
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Dementia Big
Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland.
Dementia Big
Research carried out by Plymouth University into the experience of dementia in farming and farming families, and its impact on their businesses and home lives, has identified four areas of concern which need to be addressed if dementia in the countryside is to be managed. It is the first time that research has addressed this issue in farming.
Dementia Big
New research published online in The FASEB Journal, suggests that carriers of the Apolipoprotein E4 allele, which is the single strongest genetic predictor of Alzheimer’s disease and is associated with cognitive decline and cardiovascular disease, may have a reduced risk of cognitive decline associated with parasitic diseases.
Dementia Big
Rutgers University scientists have discovered a molecular pathway in the brain that may help provide answers to long-term memory problems in the elderly and aid researchers in identifying drug-based therapies to prevent dementia.
Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
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In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit to older adults with obesity than the benefit it provided to older adults without obesity.
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In a new research report published online in The FASEB Journal, scientists used mice to show that chicoric acid, a component of chicory, may help reduce memory impairment associated with Alzheimer’s disease, and possibly other neurodegenerative diseases.
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A recent review article published online in The FASEB Journal points to the “trigger” for the inflammatory response, caused by the immune system, that precedes Alzheimer’s disease and other neurological conditions. Specifically, the authors show that an increase in aggregated, damaged proteins within neurons, which is a normal part of the aging brain, sets off these inflammatory responses. This observation was published online in The FASEB Journal.
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Dementia Big
Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
Dementia Big
In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit to older adults with obesity than the benefit it provided to older adults without obesity.
Dementia Big
In a new research report published online in The FASEB Journal, scientists used mice to show that chicoric acid, a component of chicory, may help reduce memory impairment associated with Alzheimer’s disease, and possibly other neurodegenerative diseases.
Dementia Big
A recent review article published online in The FASEB Journal points to the “trigger” for the inflammatory response, caused by the immune system, that precedes Alzheimer’s disease and other neurological conditions. Specifically, the authors show that an increase in aggregated, damaged proteins within neurons, which is a normal part of the aging brain, sets off these inflammatory responses. This observation was published online in The FASEB Journal.
Dementia Big
Rosemary Navarro was living in Mexico when her brother called from California. Something wasn’t right with their mom, then in her early 40s. She was having trouble paying bills and keeping jobs as a food preparer in convalescent homes.
Dementia Big
Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
Dementia Big
Have you already faltered on your New Year’s resolution to exercise regularly in 2017? Joined a gym, but only worked out two days so far? New workout gear still neatly folded with tags attached? Don’t give up your admirable ambition just yet. Instead, consider a new attitude to refocus your approach toward your exercise goal.
Dementia Big
A widespread outbreak of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) at a long-term dementia care ward infected 73 percent of patients, demonstrating the serious challenges in mitigating the spread of infectious diseases in such settings.
Rosemary Navarro was living in Mexico when her brother called from California. Something wasn’t right with their mom, then in her early 40s. She was having trouble paying bills and keeping jobs as a food preparer in convalescent homes.
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Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
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Have you already faltered on your New Year’s resolution to exercise regularly in 2017? Joined a gym, but only worked out two days so far? New workout gear still neatly folded with tags attached? Don’t give up your admirable ambition just yet. Instead, consider a new attitude to refocus your approach toward your exercise goal.
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A widespread outbreak of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) at a long-term dementia care ward infected 73 percent of patients, demonstrating the serious challenges in mitigating the spread of infectious diseases in such settings.
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A comprehensive review of research published today in The Journal of the American Osteopathic Association finds delirium to be an often-undiagnosed syndrome, affecting nearly 18 percent of long-term care residents, with a staggering 40 percent one-year mortality rate.
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Dementia Big
A comprehensive review of research published today in The Journal of the American Osteopathic Association finds delirium to be an often-undiagnosed syndrome, affecting nearly 18 percent of long-term care residents, with a staggering 40 percent one-year mortality rate.
A new study from the University of Eastern Finland shows that a relatively high intake of dietary cholesterol, or eating one egg every day, are not associated with an elevated risk of dementia or Alzheimer’s disease.
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Dementia Big
A new study from the University of Eastern Finland shows that a relatively high intake of dietary cholesterol, or eating one egg every day, are not associated with an elevated risk of dementia or Alzheimer’s disease.
Dementia Big
New research findings show that bilingual people are great at saving brain power, that is. To do a task, the brain recruits different networks, or the highways on which different types of information flow, depending on the task to be done.
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A new pilot study led by McLean Hospital’s Ipsit Vahia, MD, medical director of Geriatric Psychiatry Outpatient Services at McLean Hospital, suggests that the use of tablet computers is both a safe and a potentially effective approach to managing agitation among patients with dementia.
New research findings show that bilingual people are great at saving brain power, that is. To do a task, the brain recruits different networks, or the highways on which different types of information flow, depending on the task to be done.
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A new pilot study led by McLean Hospital’s Ipsit Vahia, MD, medical director of Geriatric Psychiatry Outpatient Services at McLean Hospital, suggests that the use of tablet computers is both a safe and a potentially effective approach to managing agitation among patients with dementia.
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Dementia Big
A new pilot study led by McLean Hospital’s Ipsit Vahia, MD, medical director of Geriatric Psychiatry Outpatient Services at McLean Hospital, suggests that the use of tablet computers is both a safe and a potentially effective approach to managing agitation among patients with dementia.
Dementia Big
Biomarkers that identify individuals at risk of Alzheimer’s disease (AD) development would be highly valuable. Plasma concentration of amyloid β (Aβ)—central in the pathogenesis of AD—is a logical candidate, but studies to date have produced conflicting results on its utility.
A new pilot study led by McLean Hospital’s Ipsit Vahia, MD, medical director of Geriatric Psychiatry Outpatient Services at McLean Hospital, suggests that the use of tablet computers is both a safe and a potentially effective approach to managing agitation among patients with dementia.
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Biomarkers that identify individuals at risk of Alzheimer’s disease (AD) development would be highly valuable. Plasma concentration of amyloid β (Aβ)—central in the pathogenesis of AD—is a logical candidate, but studies to date have produced conflicting results on its utility.
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Dementia Big
DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer’s disease (AD). The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation, is highly abundant in the brain, and is dynamically regulated by life experiences. However, little is known about its genome-wide patterns and potential role in AD.
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Elevated levels of the brain protein tau following a sport-related concussion are associated with a longer recovery period and delayed return to play for athletes, according to a study published in the January 6, 2017 issue of Neurology, the medical journal of the American Academy of Neurology.
Elevated levels of the brain protein tau following a sport-related concussion are associated with a longer recovery period and delayed return to play for athletes, according to a study published in the January 6, 2017 issue of Neurology, the medical journal of the American Academy of Neurology.
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DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer’s disease (AD). The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation, is highly abundant in the brain, and is dynamically regulated by life experiences. However, little is known about its genome-wide patterns and potential role in AD.
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Dementia Big
Patients who had a diagnosis of Parkinson’s disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels of Alzheimer’s disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania.
Patients who had a diagnosis of Parkinson’s disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels of Alzheimer’s disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania.
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Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next.
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Dementia Big
Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next.
Researchers of the German Center for Neurodegenerative Diseases have found that “alpha-synuclein”, a protein involved in a series of neurological disorders including Parkinson’s disease, is capable of travelling from brain to stomach and that it does so following a specific pathway.
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Treatment with an inhibitor of 12/15-lipoxygenase, an enzyme elevated in patients with Alzheimer’s disease (AD), reverses cognitive decline and neuropathology in an AD mouse model, reports a new study in Biological Psychiatry. The effects were observed after the AD-like phenotype was already established in the mice, which is promising for its potential therapeutic use, as neuropathology tends to develop many years before the appearance of AD symptoms in patients.
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(Medical Xpress)—A team of researchers working at the National Institutes of Health in the U.S. and the University College London Institute of Neurology in the U.K. has found what appears to be a correlation between fibril formation types in the brain and Alzheimer’s subtypes. In their paper published in the journal Nature, the team describes their examination of the brains of deceased Alzheimer’s patients and what they found by comparing amyloid-beta peptide deposits with progression types.
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People living within 50 meters of a busy road are at an increased risk of developing dementia, compared with people who live further away, according to research published in The Lancet.The study also analyzed the link between traffic pollution exposure and the risk of Parkinson’s disease…
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Dementia is more common in people who live within 50 metres of a major road than those who live further away, according to a study looking at 6.6 million people published in The Lancet. However, the study found no link between traffic exposure and Parkinson’s disease or multiple sclerosis.
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A study published today in the Journal of Anatomy has made an important breakthrough in the examination of blood vessels in the brain giving scientists a clearer understanding of how dementia, brain cancer and stroke can affect veins and capillaries in this organ.
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Dementia Big
Researchers of the German Center for Neurodegenerative Diseases have found that “alpha-synuclein”, a protein involved in a series of neurological disorders including Parkinson’s disease, is capable of travelling from brain to stomach and that it does so following a specific pathway.
Dementia Big
Treatment with an inhibitor of 12/15-lipoxygenase, an enzyme elevated in patients with Alzheimer’s disease (AD), reverses cognitive decline and neuropathology in an AD mouse model, reports a new study in Biological Psychiatry. The effects were observed after the AD-like phenotype was already established in the mice, which is promising for its potential therapeutic use, as neuropathology tends to develop many years before the appearance of AD symptoms in patients.
Dementia Big
(Medical Xpress)—A team of researchers working at the National Institutes of Health in the U.S. and the University College London Institute of Neurology in the U.K. has found what appears to be a correlation between fibril formation types in the brain and Alzheimer’s subtypes. In their paper published in the journal Nature, the team describes their examination of the brains of deceased Alzheimer’s patients and what they found by comparing amyloid-beta peptide deposits with progression types.
Dementia Big
People living within 50 meters of a busy road are at an increased risk of developing dementia, compared with people who live further away, according to research published in The Lancet.The study also analyzed the link between traffic pollution exposure and the risk of Parkinson’s disease…
Dementia Big
Dementia is more common in people who live within 50 metres of a major road than those who live further away, according to a study looking at 6.6 million people published in The Lancet. However, the study found no link between traffic exposure and Parkinson’s disease or multiple sclerosis.
Dementia Big
A study published today in the Journal of Anatomy has made an important breakthrough in the examination of blood vessels in the brain giving scientists a clearer understanding of how dementia, brain cancer and stroke can affect veins and capillaries in this organ.
Available data and models for the health-economic evaluation of treatment in Alzheimer's disease (AD) have limitations causing uncertainty to decision makers. Forthcoming treatment strategies in preclinical or early AD warrant an update on the challenges associated with their economic evaluation.
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Dementia Big
A new study shows that older people who followed a Mediterranean diet retained more brain volume over a three-year period than those who did not follow the diet as closely.
Dementia Big
Available data and models for the health-economic evaluation of treatment in Alzheimer's disease (AD) have limitations causing uncertainty to decision makers. Forthcoming treatment strategies in preclinical or early AD warrant an update on the challenges associated with their economic evaluation.
Dementia Big
This article updates the Calcium Hypothesis of Alzheimer’s disease and brain aging on the basis of emerging evidence since 1994 (The present article, with the subtitle “New evidence for a central role of Ca2+ in neurodegeneration,” includes three appendices that provide context and further explanations for the rationale for the revisions in the updated hypothesis—the three appendices are as follows: Appendix I “Emerging concepts on potential pathogenic roles of [Ca2+],” Appendix II “Future studies to validate the central role of dysregulated [Ca2+] in neurodegeneration,” and Appendix III “Epilogue: towards a comprehensive hypothesis.”) (Marx J.
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Members of the dementia research community may submit abstracts through 11:59 p.m. EST, January 30, for an opportunity to present at the Alzheimer’s Association International Conference® (AAIC) 2017, which will take place July 16-20, 2017, in London, England. Preconferences and educational workshops will be held July 14 and 15. The abstract submission deadline is February 2 for members of the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART).
Dementia Big
Members of the dementia research community may submit abstracts through 11:59 p.m. EST, January 30, for an opportunity to present at the Alzheimer’s Association International Conference® (AAIC) 2017, which will take place July 16-20, 2017, in London, England. Preconferences and educational workshops will be held July 14 and 15. The abstract submission deadline is February 2 for members of the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART).
This article updates the Calcium Hypothesis of Alzheimer’s disease and brain aging on the basis of emerging evidence since 1994 (The present article, with the subtitle “New evidence for a central role of Ca2+ in neurodegeneration,” includes three appendices that provide context and further explanations for the rationale for the revisions in the updated hypothesis—the three appendices are as follows: Appendix I “Emerging concepts on potential pathogenic roles of [Ca2+],” Appendix II “Future studies to validate the central role of dysregulated [Ca2+] in neurodegeneration,” and Appendix III “Epilogue: towards a comprehensive hypothesis.”) (Marx J.
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Members of the dementia research community may submit abstracts through 11:59 p.m. EST, January 30, for an opportunity to present at the Alzheimer’s Association International Conference® (AAIC) 2017, which will take place July 16-20, 2017, in London, England. Preconferences and educational workshops will be held July 14 and 15. The abstract submission deadline is February 2 for members of the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART).
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Members of the dementia research community may submit abstracts through 11:59 p.m. EST, January 30, for an opportunity to present at the Alzheimer’s Association International Conference® (AAIC) 2017, which will take place July 16-20, 2017, in London, England. Preconferences and educational workshops will be held July 14 and 15. The abstract submission deadline is February 2 for members of the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART).
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