Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer’s disease, primary tauopathies, and other dementias

Aggregation of tau is a hallmark of many neurodegenerative diseases, and tau imaging with positron emission tomography (PET) may allow early diagnosis and treatment monitoring. We assessed binding of the PET tracer [18F]AV-1451 in a range of dementias.

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