Selecting for neurogenic potential as an alternative for Alzheimer's drug discovery

Selecting for neurogenic potential as an alternative for Alzheimer's drug discovery:

Dementia Big
Neurons die in Alzheimer’s disease (AD) and are not effectively replaced. An alternative approach to maintain nerve cell number is to identify compounds that stimulate the proliferation of endogenous neural stem cells in old individuals to replace lost neurons. However, unless a neurogenic drug is also neuroprotective, the replacement of lost neurons will not be sufficient to stop disease progression.

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