3-D imaging reveals unexpected arrangement of plaques in Alzheimer's-afflicted brains

Rockefeller University researchers have used a recently-developed imaging technique that makes tissue transparent to visualize brain tissue from deceased patients with Alzheimer’s disease, exposing nonrandom, higher-order structures of beta amyloid plaques—sticky clumps of a toxic protein typically found in the brains of people with Alzheimer’s. The findings appear July 14 in Cell Reports.

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