Study findings suggest how progranulin deficiency causes frontotemporal dementia

Study findings suggest how progranulin deficiency causes frontotemporal dementia:

Dementia Big
In a recent study in Human Molecular Genetics, researchers from VIB and KU Leuven led by prof. Philip Van Damme, reveal a novel function for progranulin in lysosomes: it acts as chaperone of the lysosomal protease cathepsin D. The results were obtained in collaboration with Prof. Paul Saftig from the University of Kiel.

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