We thank Mapstone et al. for their comments on our failure to replicate their index findings on plasma metabolite biomarkers of incident Alzheimer disease (AD) [1]. They raise three main concerns with our study [2] which they suggest precludes comparison with their earlier report. We respond to each of these in the following sections:
from Dementia Big http://ift.tt/2k2CaD7 via alcoholic dementia
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