The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model

The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model:

Dementia Big
The Dominantly Inherited Alzheimer Network Trial Unit (DIAN-TU) is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs to the platform, designated as the Next Generation (NexGen) prevention trial.

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